"Agapurin": ntuziaka maka ojiji, n'ezie na

Gịnị bụ ọgwụ "Agapurin"? Ntuziaka maka ojiji, ntọhapụ ụdị na ihe ndị mejupụtara nke ego ga-ọkọnọ a obere n'ihu. Ke adianade do, ke ibuotikọ emi ị ga-amụta banyere ikpe nke ọgwụ na-kenyere mgbe na ya iji na-nditịm ajuru aju, ma o nwere mmetụta na na.

The mejupụtara na ụdị ọgwụ

Ọ bụ n'ebe ahụ mba aha ke "Agapurin" ọgwụ ọjọọ? "Pentoxifylline" - nke a bụ ya nke abụọ aha.

Ugbu ọgwụ dị na abụọ dị iche iche iche:

1. Biconvex mbadamba ntekwasa (ọcha) na-enwe a kenkowaputa na-enwu. A ọgwụ nwere n'ọrụ akụrụngwa bụ pentoxifylline na ndị ọzọ bekee (lactose monohydrate, oka starch, colloidal anhydrous silica, talc na magnesium stearate). Na-akwanyere ndị shei, ọ na-agụnye ọcha dị ka carmellose sodium, crystalline sucrose, powdered sucrose, talc, methylparaben, titanium dioxide, silica colloidal anhydrous na acacia.
2. Solution (doro anya, colorless) maka ogwu ogbugba. Nke a agwọ ọrịa na-agụnye pentoxifylline, sodium chloride na mmiri ogwu ogbugba.

M ga-amasị banyere eziokwu na ndị dị otú a ọgwụ analogue nwere ike dị na ahịa ọgwụ ígwè dị ka "Agapurin ghara". Ntụziaka nke ọgwụ na-ekwu na ọ bụ onye na gị n'ụlọnga nke ruo ogologo oge ihe. Na ọ bụ dị mbadamba, nke na-ntekwasa na a film mkpuchi. Nke a na ọgwụ nwere pentoxifylline na ndị ọzọ ọcha dị ka hypromellose, povidone, talc, na magnesium stearate.

pharmacological Njirimara

Gịnị bụ ọgwụ "Agapurin"? Ntuziaka maka Iji na-ekwu na nke a gị n'ụlọnga bụ antispasmodic na bụ nke purine otu. Ọ budata mma ọbara, nakwa dị ka ya rheological Njirimara. The ọrụ ụkpụrụ nke si agwọ ọrịa bụ phosphodiesterase mgbochi, na-amụba ọdịnaya nke ATP na erythrocytes na mara ụlọikwuu na platelet na bullet saturation ike nwere. Nke a na-vasodilation na ẹsụhọde ngụkọta vaskụla eguzogide (elu), na nkeji na-amụba strok olu enweghị a ịrịba mgbanwe obi ọnụego.

The usoro nke edinam nke ọgwụ

Gịnị bụ usoro nke edinam "Agapurin" ọgwụ ọjọọ? Ntuziaka maka ojiji na-enye ihe ike ịgwụcha agwụcha azịza nke ajụjụ a. Mgbe n'itinye agwọ ọrịa dilate akwara akwara, na mgbe ahụ na-amụba oxygen nnyefe na akpa ume arịa na myocardium, ọ bụ antianginal mmetụta na mma oxygenation nke ọbara.

Ọ kwesịkwara kwuru na ọkọnọ Nwa ike nke na-amụba ụda nke akụkụ okuku ume musculature, akpan akpan nke diaphragm na intercostal uru.

Mgbe igba ogwu n'akwara ọgwụ ọ na-eduga ụba nnochianya mgbasa, nakwa dị ka ihe na-abawanye na ọbara olu-eru site na 1-tsu-ngalaba. Ke adianade do, a ọgwụ na-akpata na-abawanye na ọdịnaya nke adenosine na ụbụrụ na nwere mmetụta bara uru na bioelectrical ọrụ nke ụjọ usoro.

Dị ka ntụziaka, kwuru, sị agwọ ọrịa bụ ike nke na mbenata viscosity nke ọbara, dịkwuo ekwedo nke erythrocyte akpụkpọ ahụ ma melite microcirculation na mkpọchị mgbasa.

Olee ihe nwere na nkà mmụta ọgwụ "Agapurin"? Ntuziaka maka ojiji na-ekwu na na ọbara occlusive ọrịa (elu) ifịk ọgwụ nwere ike ime ka mkpochapu n'abalị cramps na umu-ehi, na elongation anya nke na-eje ije na ihe mgbu na-ezu ike.

Pharmacokinetics

Medicine "Agapurin" na-ngwa ngwa metabolized na imeju. Nke a na-arụpụta n'ọrụ metabolites. Ha ịta n'ime ọbara ọtụtụ ugboro elu karịa ịta nke bụ isi umi.

Ngosipụta ọkọnọ agwọ ọrịa dị ka metabolites na ego nke 94%, na ndị fọdụrụnụ - site na eriri afọ. N'oge mbụ 4 awa mgbe ingestion nke ọgwụ tọhapụrụ ke ichekwa 90% nke Dosages eji. Ke unmodified ụdị, ọ na-egosipụta na a olu nke 2%. Ọ kwesịkwara kwuru na-arụsi ọrụ ike umi na metabolites nke pentoxifylline anaghị kee ọbara na-edozi.

Mgbe isi ọrụ nke akụrụ decelerates mmepụta metabolites. Ọ bụrụ na imeju ọrụ abnormalities hụrụ ogologo oge ọkara ndụ, na ụba bioavailability.

Drug "Agapurin" (mbadamba): ntuziaka maka ojiji

Dị ka mmasị ntuziaka ka ndị agwọ ọrịa, ọ ga-a na otu na otu oge nke ụbọchị mgbe eri nri, na-aṅụ mmiri nkịtị. The ọgwụ bụ ihe ọ bụla ikpe agaghị ekwe omume na-ata.

Mbụ onunu ogwu nke ọgwụ bụ 200 mg ugboro atọ n'ụbọchị. Ọ bụrụ na onye ọrịa na-a ogologo oge ọgwụgwọ ma ọ bụ ama ogbenye ndidi nke ọgwụ, mgbe ahụ, a otu dose nwere ike belata kpọmkwem ugboro abụọ, ma na-ọnụ ọgụgụ nke oriri.

Pụtara kwa onunu ogwu ekwesịghị gafere 1200 mg.

Ugbu a ị maara otú e si eji ọgwụ ọjọọ, "Agapurin" (mbadamba). yiri n'aka maka ngwa ntụziaka na ogologo ntọhapụ e dere ozi banyere otu Dosages. Otú ọ dị, mgbe na-eji ya na o kwere omume iji belata multiplicity n'ikuku.

Ntuziaka maka ojiji nke ihe ngwọta maka ọgwụ

Olee otú iji ndị ọgwụ ọjọọ, "Agapurin"? Mbadamba na-kenyere ọzọ ọtụtụ ugboro karịa injectable ngwọta. Ọ bụrụ na n'ihi ihe ọ bụla na-enwe ndidi na-apụghị iri Ịṅụ ọgwụ, ọ kenyere injections.

Nke a nkwadebe ere ngwọta ụdị n'ihi ọgwụ ike ga-ndinọ site na otu nke ụzọ ya:

1. Too ogologo. Ọdịnaya nke ampoule ga-diluted na 5% glucose ngwọta ma ọ bụ na 250-500 ml chloride (0.9%) sodium chloride. The ọgwụ ga-ndinọ nwayọọ nwayọọ, ọ bụghị ihe karịrị 150 ml kwa awa. Ọ bụrụ na onye ọrịa anabata ọgwụ, kwa ụbọchị dose kwere ntọt ruo abụọ ampoules, ie 200 mg.
2. Intramuscularly. The ọgwụ na-ndinọ na 100 mg ugboro abụọ n'ụbọchị. Ọ na-adịghị itughari ọdịnaya nke vial.
3. Intraarterially. Ọgwụgwọ nke onye ọrịa ga-amalite na ochichi nke a otu ampoule, nke a ga-eji-diluted na 20-50 ml nke isotonic sodium chloride ngwọta. Ọ bụrụ na ị chọrọ ruo ogologo oge ọrịa, ndị dose nwere ike mụbara 2-3 ampoules. Ha ga-diluted 30-50 ml.

Ọ ga-kwuru na kacha ego nke agwọ ọrịa a na-kpebisie ike na site a dibịa, ma naanị na ọ na otu onye ọrịa ndụmọdụ.

Agwọ ọrịa "Agapurin": egosi maka ojiji

Tupu iji a ọgwụ, ị kwesịrị ịkpọ dọkịta gị ma na-anwale. Mgbe niile, na nkà mmụta ọgwụ na-kenyere naanị n'okpuru ụfọdụ deviations. The ndepụta anyị ga-atụlekwu.

1. Trophic ọrịa nke anụ ahụ na pụta megide backdrop nke ogbenye venous ma ọ bụ ọbara microcirculation (dị ka ure anụ, varicose ọnyá, frostbite, na na.).
2. Ọbara ọrịa (elu) nke a na-guzobere n'ihi nke mkpali, atherosclerotic na-arịa ọrịa shuga Filiks. ọgwụ dị ka kenyere "intermittent" claudication, nke e mere site atherosclerosis, ọbara occlusive ọrịa, na-arịa ọrịa shuga angiopathy.
3. -Adịghị ala ala na nnukwu ischemic ọrịa strok, nke bụ ischemic malite. Ọzọkwa, ọgwụ na-eji na -arịa ọrịa ọrịa mgbasi akwara, paresthesia, angioneyropatii, Raynaud ọrịa na akrozianoz.
4. Mkpọchị mgbasa ke nile nke visual akụkụ (nnukwu na-adịghị ala ala ọbara ọdịda, vaskụla na ntupu membranes nke anya).
5. State ịda mgbe ischemic ma ọ bụ hemorrhagic ọrịa strok.
6. Ọrịa nke etiti ntị vaskụla si, nke na-ebu na-anụ ọnwụ.

Contraindications ojiji nke

Mgbe i nwere ike iji ọgwụ "Agapurin"? The ojiji nke a ọgwụ na-aju n'okpuru ndị na-esonụ na ọnọdụ na deviations:

• nnukwu myocardial infarction;
• owụt akwara ma ọ bụ ọrịa ụbụrụ ọrịa mgbasi akwara;
• owụt ịda iwu nke obi n'afọ iri na ụma;
• porphyria;
• n'echeghị echiche ọbara hypotension;
• oke ọbara ọgbụgba;
• nnukwu hemorrhagic ọrịa strok;
• retinal hemorrhage;
• afọ ime, ara;
• afọ 18 afọ (nchekwa na nrụpụta ọrụ adịghị ike);
• hypersensitivity ka pentoxifylline, na ọcha si otu xanthine emepụta.

Akọ ojiji nke ọgwụ

Na oke-elekọta ngwá ọrụ na-etinyere ọrịa na a ọchịchọ ọbara hypotension, labile ọbara mgbali, obi ọdịda (adịghị ala ala), a ọchịchọ hemorrhage, gbasara akụrụ na hepatic insufficiency, na na-na ọnọdụ mgbe ịwa ahụ.

mmetụta

È nwere mmetụta si ọgwụ, "Agapurin"? Mbadamba ndu nke na-dị n'elu, nakwa dị ka ihe ngwọta maka ọgwụ nwere ike ime ka a ọnụ ọgụgụ nke njọ. Ka anyị tụlee ha na ihe zuru ezu.

• Digestive usoro: cholestatic ịba ọcha n'anya, nsia atony, nkpasu-iwe cholecystitis, akọrọ ọnụ na ọnwụ nke agụụ.
• Ụjọ usoro: nchegbu, ehighi ura, dizziness, cramps na isi ọwụwa.
• Ọbara arịa na akpụkpọ: ozizi, kenkuwa mbọ, ọdịdị ihu flushing, flushing n'elu nke obi na ihu.
• Obi usoro: arrhythmia, ụgha rịaworo, aga n'ihu rịaworo pectoris, tachycardia na ala ọbara mgbali.
• Ozu hematopoiesis na hemostasis usoro: thrombocytopenia, leukopenia, pancytopenia, gipofibrinogenemia si nsia agba ọbara, afo, subcutaneous capillaries na mucous membranes.
• Sensory akụkụ: isi ọhụụ na scotoma.
• Nfụkasị Jeremaya: pruritus, urticaria, angioedema , na anaphylaxis.

ikpe nke ovadozu

Gịnị na-eme ma ọ bụrụ na ị na-eji elu doses ọgwụ "Agapurin" (400 mg, 600 mg, 1200 mg)? Na nke a, ọrịa nwere ike dị otú ahụ na-enweghị nchịkwa na mgbaàmà dị ka adịghị ike, akara Mbelata ke ọbara mgbali, dizziness, tachycardia, syncope, somnolence, generalized tonic-clonic ọdịdọ, ọnwụ nke nsụhọ, hyperthermia, ogwe, eriri afọ na-agba ọbara mgbaàmà (eg, vomiting " kọfị mgbakwasị ") na areflexia.

Na nke a na-achọ ngwa ngwa symptomatic ọgwụgwọ nke na-eduzi na ịnọgide na-enwe nkịtị ọbara mgbali na akụkụ okuku ume ọrụ.

Specific ntuziaka maka ojiji nke ọgwụ

Ihe i kwesịrị ịma tupu ị na-eji ọgwụ "Agapurin"? Nyocha nke dọkịta na-ekwu na nkà mmụta ọgwụ dị mma na ọrụ a, ma ọgwụgwọ dị mkpa ka ha n'okpuru ike akara nke ọbara mgbali. Na nke a, na ọrịa obi na odida (adịghị ala ala) a chọrọ iji nweta ụgwọ mgbasa.

Ọ kwesịkwara kwuru na ọrịa na a nchoputa nke "ọrịa shuga" na-ewere hypoglycemic ọgwụ ọjọọ, na ojiji nke a gị n'ụlọnga ke nnukwu doses na-akpata a akpọ hypoglycemia. Ya mere dose ukpụhọde dị mkpa maka ha.

Na n'otu oge ojiji nke ọgwụ na anticoagulants ga-akpachara anya nyochaa ọnọdụ nke ọbara coagulation usoro.

Na ọrịa ndị na-adịbeghị anya nwere ịwa ahụ, i kwesịrị mgbe niile nyochaa ịta nke haemoglobin na hematocrit.

The ndinọ onunu ogwu ga-ebelata ke ọrịa na-ejighị n'aka ma ọ bụ ala ọbara mgbali.

Ndị agadi nwere ike mkpa a nta dose.

Dị ka ọmụmụ, ise budata ebelata ọgwụgwọ nrụpụta ọrụ nke ọgwụ.

pentoxifylline ndakọrịta na ndị ọzọ infusion ngwọta ga-enyocha na onye ọ bụla ikpe.

Mmekọrịta ọzọ n'aka

N'ọrụ umi pentoxifylline mgbe enhances ihe nke mmadụ na-emetụta ọbara clotting. Ndị dị otú ahụ ọgwụ ọjọọ eme ihe na-agụnye kpọmkwem anticoagulants, valproic acid, thrombolytics, na anitibiotiki (e.g., ọgwụ ọjọọ "Tsefamandol", "Cefoperazone", "tsefotetan").

Sị na gị n'ụlọnga enwekwu irè nke onu hypoglycemic na antihypertensive ọgwụ ọjọọ, dị ka nke ọma dị ka insulin.

Anyị apụghị ikwu na ọgwụ "cimetidine" budata enwekwu ịta nke pentoxifylline ke iyịp. A na-enwekwu ihe ize ndụ nke mmetụta.

Co-nlekọta "Agapurin" ọgwụ ọjọọ, reviews nke na-egosi n'okpuru, na ndị ọzọ xanthines eduga oké ụjọ obi ụtọ.

Ụzọ maka nkwadebe nchekwa, reviews ya, price

Drug "Agapurin" a na-eresị na ọ fọrọ nke nta ọ bụla na-ere ọgwụ. Zụrụ 60 mbadamba (100 mg), ị ga-enwe ike achapu nanị ihe karịrị 250 Russian rubles.

Nleba a agwọ ọrịa bụ ihe ziri ezi. Ọ bụ ya mere ọ na-ọgwụ ọjọọ ndị ọzọ ọgwụ ọrịa ndị nwere nsogbu na ọbara arịa.

Ọ kwesịkwara kwuru na a pụtara nnukwu-ewu ewu na nkà mmụta ọgwụ "Agapurin" na bodybuilding. Nyocha bodybuilders na-ekwu na ngwá ọrụ a ga-atụle iche site na ọgwụ ọjọọ ndị ọzọ na mma ọbara. Mgbe niile, ọ bụ ihe kasị dị irè ma ego.

Active agwọ ọrịa nke bụ na-eme egwuregwu, dị ka ọ na-emepụta ọ bụghị nanị na ọdịdị nke ihe injectable ngwọta, ma na-na mbadamba ụdị. Pharmacies ngwá ọrụ a pụrụ ịchọta n'okpuru aha ndị ọzọ na-ada ka "Pentoxifylline" ma ọ bụ "Trental".

The isi ọrụ na-anọchi anya ọgwụ omume ụba ụda ọbara arịa, mbenata ọbara viscosity ma na-amụba ọbara. All nke a bụ oké ụzọ mezuo pumping na egwuregwu ọzụzụ, mgbe e nwere mmetụta nke ike na-arụ ọrụ uru pumping.

Jiri a ọgwụ nwetara bodybuilders kwesịrị ịkpachara nnọọ anya, n'ihi na ọ nwere ike mfe ime ka ihe ovadozu na a ọnụ ọgụgụ nke mmetụta.

Nọgidenụ "Agapurin" ọkacha mma na a gbara ọchịchịrị, akọrọ ebe e nweghị ohere na-eto eto ụmụ. N'ihi ya nchekwa okpomọkụ nke ọgwụ bụ naanị 10-15 degrees. Ngafe ụbọchị gosiri na nkwakọ ngwaahịa na bụ afọ abụọ. Mgbe oge a, ọgwụ ọjọọ bụ ihe amachibidoro.

Ná mmechi, anyị na-arịba otu ugboro ọzọ na-ekwesịghị-onwe-inye onwe ha na-ewere ọgwụ a. Duration nke ọgwụgwọ na onunu ogwu ga-ekpebisi ike site a dibịa maka otu ndidi.