Antihypertensive mmadụ 'Enap'. Ntuziaka maka ojiji nke ọgwụ

"Enap" na-ezo aka jikọtara nkwadebe. Ọ nwere ifịk hypotensive na mamịrị ihe, dị na mbadamba, na-acha ọcha (10 nkeji na a ngwe nkwakọ).

Enap. egosi

N'etiti antihypertensive mmadụ, na-n'ọtụtụ ebe na taa na ọgwụ na ahụ ike omume, ọ enyene a pụrụ iche n'ebe ọgwụ "Enap". Ntuziaka maka were aha ọtụtụ ndị na-egosi maka ya bipụta ya, nzube:

- ọbara mgbali;

- ekpe ventricular dysfunction;

- obi ọdịda.

Rịba ama na enap atụle a prodrug, ya ọrụ na-egosi mgbe abanye ahụ, mgbe mmiri nke ọgwụ site hydrolysis etolite enalaprilat, nke n'aka nke na-egbochi Ace.

N'ihi na-arụ ọrụ bekee nke nkwadebe "Enap", na mgbakwunye na enalapril, hydrochlorothiazide bụ, nke ìgwè nke thiazide diuretics. Usoro nke jikọtara ihe nke ọgwụ bụ weere na-ebelata ibu na mmiri mmiri sodium na ọbara arịa, nke na-eduga a ọnụ ke gbasara obi mmepụta na ọbara mgbali.

Ọrịa na myocardial infarction dị ka ọgwụ "Enap" e kenyere. Ntuziaka maka ojiji na-egosi na n'ikuku nke a agwọ ọrịa dị otú ahụ ikpe nwere ike ibelata otụk ebe nke necrosis ma melite metabolism na obi muscle.

Enap mmetụta dị mma na gbasara akụrụ ọbara, ọgwụ adịghị eme ka onye na-abawanye na potassium anyụpụ, nke dị mkpa na ọbara mgbali elu. Nke a na-egbochi mmepe nke àgwà ọgwụ ọjọọ na ọrịa na gbasara akụrụ insufficiency.

Ọrịa na ọrịa obi mma ahụ ike na ọgwụgwọ pụtara "Enap". Ntuziaka maka ojiji na-agba ume ọgwụ n'ihi na Mbelata ke enwe chọpụtara na ọrịa na congestive obi ọdịda. Arụmọrụ pụtara bụghị belata dabere n'ogo nke renin n'ime ọbara plasma, ọrịa na-afọ, ya ma ọ bụ ya nwoke. dịghị nke kọwara ikpe nke na-ezighị ezi mmetụta na ọgwụ ọjọọ "Enap" mmekọahụ ọrụ na ọgwụ na ahụ ike omume. Ntụziaka kwukwara na-anọghị nke na-ezighị ezi mmetụta nke ọgwụ na lipid na carbohydrate metabolism ke idem.

"Enap" ọgwụ ọjọọ. pharmacokinetic Njirimara

Absorption nke nọ n'ọrụ gị n'ụlọnga emee predominantly site digestive tract (60%), na mmiri usoro bụ na ọ bụghị oge nke nri. Ugbua mgbe 1 hour, e nwere mmalite nke "Enap" nke ọgwụ. Guide egosi akpọ ọgwụgwọ mmetụta nke ọgwụ, nke pụtara mgbe a kacha 6 awa mgbe ochichi, ifịk ifịk ọgwụ mmetụta adịgide ruo ụbọchị.

Contraindications na mmetụta

Contraindications na ojiji nke ọgwụ ọjọọ, "Enap" ntụziaka ide:

- ụba uche nke onye ọrịa na ya mmiri;

- porphyria;

- angioedema ;

- ime;

- Lactation.

E nwere ọnụ ọgụgụ nke mmetụta na-erukwa na ụfọdụ na-ewere ọgwụ, "Enap". Guide adọ aka ná ntị megide imekotaotuugbo ọgwụgwọ nke ọrịa ndị ọzọ diuretics na pụrụ iduga mkpọchị gbasara akụrụ ọrụ. akụrụ malitegharịa iji wepụ ọgwụ.

Na obere okwu, e nwere ihe ọbara hypotension (a na-adịghị adịte agwa), ọrịa mkpesa nke ugboro ugboro isi ọwụwa. Na ụfọdụ ndị ọrịa na-ewere ọgwụ na-akpalite vomiting na ọgbụgbọ, muscle cramps na akpụkpọ rashes.

Drug "Enap". ovadozu

Isi mgbaàmà mere site ịṅụfe ọgwụ ike ókè nke a ọgwụ ọjọọ, "Enap", ntuziaka maka ojiji na-ezo aka ihe ịrịba ama nke hypotension. Mgbe mpụta ìhè nke onye ọrịa kwesịrị itinye, tinye gastric lavage na-enye ọrụ unyi. Mgbe ahụ jikoro kwesịrị iwere iji weghachi olu nke ọbara ekesa ke idem. N'ihi nke a, ọrịa na-ndinọ (intravenously) sodium chloride ngwọta, otú a ka ọ dị mkpa na-akara nile ndị dị mkpa usoro.

Iji zere hassles metụtara na ovadozu ma ọ bụ mmetụta, "Enap" nkwadebe dị mkpa tupu ewere ịkpọ dọkịta gị.