"Mesipol": ntuziaka maka ojiji, n'ezie na ogbo

Gịnị bụ ọgwụ "Mesipol"? na ngwa nke na ngwá ọrụ ndu, ya megide-egosi na a ga-atụle n'isiokwu a. Ọzọkwa, ị ga-amụta ma ma ọ bụ nke a ọgwụ mmetụta nke ahụ ga-na ihe omume nke ihe ovadozu, ọdịdị na nke ọ na-ahịa na ihe umi nwere.

Ụdị nke ọgwụ na ya mejupụtara

Nkwadebe "Mesipol" ahịa abụọ dị iche iche: mbadamba na ngwọta maka intramuscular ogwu ogbugba. Ha na-arụ ọrụ ụkpụrụ bụ otu ihe. Ọ bụrụ na ọ gaghị ekwe omume na-edeghị ede ochichi, ọgwụ na-eji.

The ngwọta "Mesipol" nwere ifịk mmewere dị ka meloxicam. Ọ na-agụnye ndị na-esonụ inyeaka Efrata: glycofurol, meglumine, sodium chloride, Poloxamer 188, sodium hydroxide, glycine, na mmiri ogwu ogbugba.

The ngwọta nwere a-acha odo odo ma ọ bụ greenish-acha odo odo. Ọ bụ uzo. Ọzọkwa ya nwere a ji mara ísì ụtọ. The katọn bụ 3 ampoules (1.5 ml).

Itunanya bu na, na mgbakwunye na mbadamba ma ọ bụ ihe ngwọta maka intramuscular injections, ọgwụ na ụlọ ọrụ ndị malitere na-emepụta kandụl "Mesipol" na suspensions zubere maka onu ochichi.

The pharmacological e ji mara nke ọgwụ

"Mesipol" ọgwụ bụ a ndị so ná ndị mgbochi mkpali n'ụlọnga. The ọgwụ na-enwe ike na-akpa ịnụ ọgwụ na antipyretic mmetụta. The antiinflammatory mmetụta nke n'aka metụtara na a slowing nke enzymatic ọrụ nke cyclooxygenase-2, nke na-agụnye ndị biosynthesis nke prostaglandins na ire ọkụ ka ebe.

Onye kasị nta ifịk meloxicam mmewere eme na cyclooxygenase-1, nke na-na-agụnye prostaglandin njikọ, nke na-echebe ndị mucous akpụkpọ ahụ nke eriri afọ na-eme na ụkpụrụ nke ọbara na akụrụ.

Pharmacokinetics nke ọgwụ

Drug "Mesipol" (injections na mbadamba) na-etinye obi gị dum kpamkpam. The bioavailability nke ọgwụ bụ 100%. Mgbe intramuscular injection (15 mg meloxicam), na kacha absorption na-ruru mgbe 65 nkeji.

anyị na-atụle ọgwụ ejikọ na plasma-edozi ahụ, gụnyere albumin (99%). Ọ na-adị mfe na-aga site na ọbara-anụ ihe mgbochi, ma penetrates n'ime synovial ọmụmụ. Ịta nime ya ka 50% nke ọgwụ ịta na plasma.

N'ọrụ umi nke agwọ ọrịa na-fọrọ nke nta kpamkpam metabolized na imeju. Nke a Nleta anọ pharmacological-adịghị ejekwa ozi metabolite.

Mgbe ngwa nke agwọ ọrịa dokwara egosipụta eriri afọ na akụrụ (a metabolite). The nkezi ọkara ndụ-nke nọ n'ọrụ umi bụ awa 20.

Egosi maka ojiji nke ọgwụ

Mgbe ụfọdụ, nye iwu ka "Mesipol"? Ntuziaka maka Iji na-ekwu na ọtụtụ mgbe nwere ike ikwu na ojiji nke NSAIDs na symptomatic ọgwụgwọ nke ọrịa ndị dị ka:

• osteoarthritis;
• ọrịa ogbu ogbu na nkwonkwo;
• Ankylosing spondylitis (ma ọ bụ ankylosing spondylitis).

Ke adianade do, ọgwụ ọjọọ, "Mesipol" (injections na mbadamba) na-kenyere ọzọ degenerative na mkpali ọrịa nke nkwonkwo, nke na-ebu oké mgbu.

Contraindications ojiji nke na-abụghị steroidal mmadụ

Mgbe ụfọdụ, ọgwụ ike ga-eji "Mesipol"? Ntuziaka maka ojiji nwere a nnukwu ndepụta contraindications. Ndị a gụnyere ndị na-esonụ:

• Hypersensitivity na-arụsi ọrụ ike mmewere nke ọgwụ ma ọ bụ ya inyeaka mmiri;
• ele mmadụ anya n'ihu ma ọ bụ zuru ezu Nchikota ụkwara ume ọkụ, ekweghị ibe nọrọ nke acetylsalicylic acid, polyposis (ntighari) paranasal imi na ọ dịghị òkè uji eze, na ndị ọzọ na NSAIDs, gụnyere anamnesis;
• ụmụ afọ (16-18 afọ);

• ọnyá ma ọ bụ erosive ọnya nke mucous akpụkpọ ahụ 12 tiperstnoj eriri afọ ma ọ bụ na afo;
• ara;
• cerebrovascular ọbara ọgbụgba ma ọ bụ ndị ọzọ na-agba ọbara si malite;
• ifịk ọbara ọgbụgba ke gootu ma ọ bụ na afo;
• n'oge gestation (ime);
• mkpali bowel ọrịa (e.g. Crohn ọrịa ma ọ bụ ọnyá afọ);
• aga n'ihu gbasara akụrụ ọrịa, gụnyere hyperkalemia (enen);
• oge mgbe akwara akwara wasịrị;
• gbasara akụrụ odida (owụt) na ndị mmadụ ndị na e doro dialysis (CC erughị 30 ml / min);
• decompensated obi odida;
• ifịk progression nke ọrịa imeju ma ọ bụ mmebi imeju (oké).

Jiri ihe ókè ịkpachara anya!

Ugbu a na ị maara na nke ikpe i nwere ike iji ọgwụ ọjọọ, "Mesipol" (mbadamba, injections), na nke ọ na-contraindicated. Otú ọ dị, e nwere ọnọdụ ndị ebe anyị tụlere ọgwụ ga-ndinọ na oké ịkpachara anya. Tụlee ndepụta dị otú ahụ ikpe:

• nká (afọ 60);
• ịrịa ọrịa obi;
• ala ala obi odida;
• cerebrovascular ọrịa;
• arịa ọrịa shuga;
• dyslipidemia ma ọ bụ hyperlipidemia;
• elu akwara ọrịa;
• creatinine nwechapụ-erughị afọ 60 ml / min;
• ise siga;
• ọnyá ọnyá nke digestive usoro na akụkọ ihe mere eme;
• ogologo oge nke na-abụghị steroidal ọgwụ ọjọọ, nakwa dị ka ha na-achịkwaghị achịkwa ojiji na nnukwu doses;
• ọrịa, mara dị ka Helicobacter pylori;
• mgbe nile na oriri nke na-aba n'anya (ọbụna na a ala ọdịnaya nke mmanya);
• otu oge ojiji nke ọnụ na corticosteroids, gụnyere "Prednisolone" ọgwụ ọjọọ;
• oké somatic abnormalities;
• concomitant ojiji nke anticoagulants (eg, ọgwụ "Warfarin"), antiplatelet elekọta mmadụ (n'ihi na ihe atụ, acetylsalicylic acid na ọgwụ "Clopidogrel"), nakwa dị ka inhibitors (nhọrọ) serotonin reuptake (gụnyere ọgwụ ọjọọ "Tsitmedialopram" "Fluoxetine", "Paroxetine" na "sertraline").

Ndị so ná ndị mgbochi mkpali ọgwụ ọjọọ, "Mesipol": ntuziaka maka ojiji

Intramuscular ochichi nke agwọ ọrịa anyị n'ihu gosiri na nke mbụ 3 ụbọchị ọgwụgwọ. N'ọdịnihu, na-ọgwụ na onu iche nke ọgwụ, ie mbadamba.

The na-atụ aro usoro onunu ogwu nke gị n'ụlọnga bụ 7.5 mg ma ọ bụ 15 mg otu ugboro n'ụbọchị. A nyere ego nke ọgwụ na-adabere na osisi ike nke ihe mgbu, dị ka nke ọma dị ka ogo nke mgbu usoro. The agwọ ọrịa na-ndinọ site miri intramuscular ogwu ogbugba.

Ọ ga-ekwe omume na ikpokọta na ọgwụ ọjọọ ndị ọzọ ọgwụ ọjọọ, "Mesipol" (gbaa)? Ntụziaka nke ọgwụ na-ekwu na ọdịnaya nke vials ọ bụla ikpe enweghị ike weere na otu ntụtụ na ndị ọzọ ngwọta. Nke a bụ n'ihi na eziokwu na e nwere a elu puru nke incompatibility nke nọ n'ọrụ umi meloxicam na ndị ọzọ ọgwụ mmiri.

Ọ ga-kwuru na ọrịa ndị na-nwere ihe ize ndụ nke oghom Jeremaya mere, nakwa dị ka akụrụ odida (owụt) on hemodialysis, a ndị so ná ndị ọgwụ onunu ogwu ekwesịghị ịbụ elu karịa 7.5 mg kwa ụbọchị.

Ọ dịkwa mkpa ka anyị cheta na ọgwụ ọjọọ, "Mesipol", analogues nke anyị ga-atụlekwu, ọ bụla ikpe na-ekwesịghị ndinọ intravenously.

The kacha kwa ụbọchị dose of meloxicam ifịk mmewere kwesịrị 15 mg. Otu ego nke ọgwụ a ga-agbaso na ikpokọta ojiji nke mbadamba, a nkwusioru maka onu ochichi, suppositories, na intramuscular ogwu ogbugba.

ikpe nke ovadozu

Enwere ikpe nke ovadozu si jiri "Mesipol" ọgwụ ọjọọ? Ọgwụ (reviews banyere ha ga-ọkọnọ ke utịt isiokwu), ọgwụ, suppositories na suspensions nwere ike ịbụ na-akpata ọrịa ndị mmadụ ma ọ bụrụ na ha na-eji n'ekweghị ngụgụ na nnukwu mpịakọta.

Mgbaàmà nke ovadozu pụrụ ịgụnye ndị na-esonụ ọnọdụ: ọgbụgbọ, mkpọchị nsụhọ, epigastric mgbu, nnukwu gbasara akụrụ odida, vomiting, na-agba ọbara na afo ma ọ bụ eriri afọ, imeju ọdịda, asystole, na akụkụ okuku ume na njide.

Gịnị na-eme bụrụ na ndị ovadozu? Ọkachamara nwere ike ikwu gastric lavage, nakwa dị ka a symptomatic ọgwụ.

Site n'ụzọ, na N'ezie nke na-adakarị ọmụmụ gosiri na cholestyramine enyere mee ngwangwa mkpochapu meloxicam. Hemodialysis ovadozu bụ adighi ike, ebe ọ bụ na a elu njikọ ọbara na-edozi.

mmetụta

Ọ nwere ike na-eme ka mmetụta ọgwụ "Mesipol" (gbaa)? na ojiji nke na-abụghị steroidal mmadụ Guide na-ekwu na ọ pụrụ ime ka a buru ibu ọtụtụ ndị ezighị ezi pụta. Ka anyị tụlee ha na ndị ọzọ zuru ezu:

• Digestive tract: dyspepsia, afọ ọsịsa, ọgbụgbọ, perforation nke digestive tract, abdominal mgbu, vomiting, flatulence, afọ ntachi, na-akwụsị akwụsị na-abawanye na transaminases (imeju), burp, hyperbilirubinemia, ọnyá ma ọ bụ erosive ọnya nke digestive usoro, esophagitis, stomatitis, doro ma ọ bụ na-ezo ọbara ọgbụgba si digestive tract, afọ, mgbu na ịba ọcha n'anya.
• Skin: ọkụ ọkụ, pruritus, bullous ọkụ ọkụ, akpụkpọ ọkụ ọkụ, photosensitivity, Stevens-Johnson syndrome, erythema multiforme, epidermal necrolysis awu.
• hemopoietic usoro: anaemia, thrombocytopenia, mgbanwe ọbara adabere na leukopenia.
• Allergy: angioedema , na anaphylaxis.
• Ụjọ System: vertigo, dizziness, mgbagwoju anya, isi ọwụwa, obi lability, tinnitus, mgbagwoju anya na iro ụra.
• Akụkụ okuku ume na usoro: bronchospasm.
• Obi usoro: a rosh ọbara na anụ ahụ, elu edema, palpitations na ọbara mgbali elu.
• Akụkụ nke ọhụụ: bịara ikiri ma ọ bụ isi ọhụụ, conjunctivitis.
• Urinary usoro: nnukwu gbasara akụrụ odida, hypercreatininemia ma ọ bụ na-abawanye na ọbara urea, interstitial nephritis, hematuria na albuminuria.
• Obodo Jeremaya mere: mgbu na-ere ọkụ na saịtị nke intramuscular ogwu ogbugba.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

• Mgbe otu oge ojiji nke ọzọ ndị so ná ndị ọgwụ ọjọọ na acetylsalicylic acid enwekwu ihe ize ndụ nke ọnyá afọ na erosive ọnya nke digestive tract, nakwa dị ka ọbara ọgbụgba na ha.
• Na n'otu oge iji ọgwụ na antihypertensives yiri ka belata irè nke ikpeazụ.
• Imekotaotuugbo ọgwụgwọ na ọgwụ "Mesipol" na lithium ọgwụ akwalite ìgwè ndị nke ikpeazụ na-amụba ya na-egbu egbu mmetụta.
• Mgbe otu oge ngwa nke "Methotrexate" pụtara ntọt ya mmetụta na hematopoietic usoro.
• Imekotaotuugbo ojiji nke ọgwụ ọjọọ, "Mesipol" na diuretics bụ ihe ize ndụ nke gbasara akụrụ odida.
• One-oge iwere na cyclosporine enwekwu nephrotoxic mmetụta nke nọ n'ọrụ umi meloxicam.
• Na n'otu oge iwere na intrauterine gbochie afọ mbelata irè nke ikpeazụ.
• Mgbe otu oge iji ihe anticoagulant na thrombolytic mmadụ na-enwekwu ihe ize ndụ nke ọbara ọgbụgba.
• Imekotaotuugbo ojiji nke a na-abụghị steroidal ọgwụ "Mesipol" na kolestiraminom enhances ya excretion site na eriri afọ akụkụ. Nke a mere dị ka a N'ihi nke nkịtị nke meloxicam.
• Disposable ọgwụ na inhibitors nke (nhọrọ) serotonin reuptake budata enwekwu ihe ize ndụ nke na-agba ọbara si eriri afọ tract.
• Myelotoxic ọgwụ ọjọọ na-amụba okwu gematotoksichnosti ifịk umi meloxicam.

Specific nduzi na iji ọgwụ ọjọọ eme

• Drug "Mesipol" kwesịrị ihe ókè ịkpachara anya na ọrịa na peptic ọnyá afọ nke afo na eriri afọ, nakwa dị ka ndị na-na anticoagulant ọgwụ.
• N'oge ọgwụgwọ na a ọgwụ dị mkpa ịchịkwa kwa nke gbasara akụrụ ọrụ, karịsịa ndị agadi na ndị ọrịa na-adịghị ala ala obi ọdịda.
• Ọrịa n'out oge na-anata diuretics na pụtara "Mesipol", ga-aṅụ ọtụtụ mmiri.
• Ọ bụrụ na N'ezie nke ọrịa, ọrịa pụtara allergies, ndị dose nke ọgwụ ga-kwụsịrị.

Analogues na ọgwụ price

Ole na-anyị na-atụle a ọgwụ? The ahịa ọgwụ injectable ụdị ọgwụ ike zụrụ maka 400 Russian rubles. Ma mbadamba, suspensions na suppositories, ha price bụ obere ala.

Gịnị ma ọ bụrụ na ị na-apụghị ịzụta ọgwụ "Mesipol"? Analogs nke ego na-ere fọrọ nke nta niile drugstores. N'etiti ha bụ ndị na-esonụ ọgwụ ọjọọ: "Amelotex", "Eksen-Sanovel", "Artrozan", "Matar", "M-cam," "free", "Medsikam", "Melbek", "Melox", "Bi- Xico "," Meloxicam "," Melox "," Meloflam "," Miksol-Aude "," Mirloks "," Movalis "," Movasin "," Moviks "," Lem "," Oksikamoks "na na.

"Mesipol": reviews nke agwọ ọrịa

Ugbu a, ị mara na bụ ọgwụ anyị na-atụle. Ọ bụ oge iji chọpụta ihe ọrịa na-ekwu banyere "Mesipol" nkwadebe. Nyocha nke a ndị so ná ndị mgbochi mkpali ambiguous n'aka. Na otu aka, ọrịa na-ekwu na ọ bụ nke ọma aka mgbu ọrịamkpokọta na ndị pụta ụwa osteoarthritis, ọrịa ogbu na nkwonkwo, ankylosing spondylitis na ndị ọzọ degenerative na mkpali oria nkwonkwo. N'aka nke ọzọ, ndị ọrịa na-emekarị mkpesa na ọgwụ na-akpata a pụtara nnukwu ọnụ ọgụgụ nke mmetụta, dị ka a N'ihi nke a ha na-amanye ịkwụsị ịṅụ ya.

Ke ofụri ofụri, ọgwụ tupu anyị "Mesipol" kpamkpam si anagide ya ọrụ.