Ọgwụ "Hydroxyzine": ntuziaka maka ojiji, analogs na reviews

Diphenylmethane nkwekọrịta nke umi bụ a n'aka "Hydroxyzine". User ngwa na-ekwu na umi bụ a na-acha ọcha dị mma ntụ ntụ, soluble na mmiri na odorless. 374,9 grams kwa ahumachi bụ molekụla arọ nke compound.

Clinico-pharmacological otu

The ọgwụ nwere ogwuura, anxiolytic mmetụta. Nke a na-akọwa inhibitory utịp ke ọrụ nke ụfọdụ subcortical owuwu nke Central ụjọ usoro dị ka nke ọma dị ka a igbochi ihe na Central H_1-histamine na m-cholinergic anabata.

"Hydroxyzine" ọgwụ analogues nwere a akpọ ogwuura na nwayọọ anxiolytic ọrụ. Nwere a na-akpali akpali mmetụta cognitive ikike, mma anya na ebe nchekwa. Maara ihe gbasara mmụọ na nduzi na riri ahụ na-adịghị ime mgbe ogologo oge ojiji nke syndrome na-adịghị hụrụ. Ọzọkwa gosipụtara anticholinergic, antihistamine, antispasmodic edinam. "Hydroxyzine" aka mgbu nke ezigbo muscle, si otú eme bronchodilatory na analgesic mmetụta, nwere antiemetic edinam na a agafeghị oke inhibitory utịp ke gastric secretion. . Hives, dermatitis, eczema, itching, wdg mbelata n'oge ọgwụ pụtara "Atarax" (hydroxyzine - ifịk umi).
Guide na-ekwu na ogwuura a na-enweta, na-emekarị n'ime 10 na 45 nkeji mgbe ingestion (dabere na ụdị nke ọgwụ), mgbochi histamine - otu awa mgbe ingestion. Na ọrịa na-ata ahụhụ si na ọrịa imeju, ihe antihistaminic mmetụta pụrụ anya n'ime 96 awa.

Ọ bụghị akara mutagenic na carcinogenic edinam nke ọgwụ.

Pharmacokinetics

Mgbe ingested ọgwụ na-ngwa ngwa etinye obi gị dum na eriri afọ tract, C_max e n'ime awa abụọ. Nkwadebe "Hydroxyzine" gabiga Plasenta na ọbara-ụbụrụ mgbochi (ogo ịta na nwa ebu n'afọ na nsụkọrọ ukwuu karịa na nne nwa anụ ahụ). Na usoro nke hepatic metabolism kpụrụ cetirizine - isi metabolite. Uru T_1 / 2 n'agbanyeghị afọ ndụ nke onye ọrịa na pụrụ ịbụ 7 awa maka ụmụ noo 2-10 afọ, 20 awa n'ihi na ndị okenye, 29 awa maka ndị agadi na ndị agadi; na-arịa ọrịa imeju nwere ike ụba na awa 37. Mkpochapu a rụrụ n'ihi na ọtụtụ akụkụ site na akụrụ (0.8% ke akpasarade ụdị).

egosi

"Hydroxyzine Hydrochloride" a na-eji:

• kpochapụ nchegbu na hyperexcitability nke ụjọ usoro;
• n'oge ndọrọ ego na ndị mmadụ n'otu n'otu na-ata ahụhụ nke na-aba na nduzi;
• ọgwụgwọ ọgwụgwọ nke psychoneurotic ọrịa;
• dị ka akụkụ nke mbara ọgwụgwọ na postoperative oge na mgbe ụfọdụ unan;
• premedication;
• iji belata esịtidem nchegbu, generalized nchegbu, ukpụhọde mgbake Filiks, na ọgwụgwọ nke systemic ọrịa;
• iji kpochapụ ihe mgbaàmà nke eczema, itchy dermatosis, urticaria, atopic dermatitis;
• maka antiemetic edinam gosiri.

Contraindications ọgwụ "Hydroxyzine Canon"

Nyocha nke dọkịta na-egosi na ọgwụ na-adịghị atụ aro iji na-enweta:

• ọrịa na-ata ahụhụ si glaucoma;
• prostate hypertrophy (prostate);
• ọrịa na onye e nwere mụbara ọdịdọ ọrụ;
• ọrịa na myasthenia gravis;
• ọrịa ndị a chọpụtara gbasara akụrụ na hepatic ọdịda;
• ọrịa na mgbaka.

The ọgwụ na-contraindicated na:

• ụmụ nwaanyị dị ime;
• ọrịa na porphyria;
• ara oge (oge nke ọgwụgwọ hapụ ara mmiri ara nne);
• anabata ngosipụta maka emejupụta mgwa (dị ka ndị ahụ ebe mbụ akara hypersensitivity ọzọ emepụta cetirizine, aminophylline, piperazine ma ọ bụ ethylene diamine);
• n'oge ọrụ na nnyefe.

About mmetụta

Ọrịa nwere ike na-ata ahụhụ si na-ehi ụra, na-eme ememe general adịghị ike, dizziness na isi ọwụwa na mmalite nke usoro ọgwụ "Hydroxyzine". Nyocha nke ọrịa emeso ya na nke a gị n'ụlọnga, na-ekwu na-esonụ mmetụta:

• nfụkasị Jeremaya, palpitations, ọgbụgbọ;
• urinary njigide, na ntachi;
• nkụ nke anya mucous membranes, mụbara sweating;
• bịara ikiri ọhụụ (ikekwe a mebiri nke ulo);
• ẹsụhọde ọbara mgbali, mụbara imeju enzyme ọrụ;
• nwere ike bronchospasm.

Nnọọ obere ediyarade ọdịdọ, tremor na mgbagwoju anya, ataxia, paradoxical mmalite na ụba moto ọrụ na ojiji nke ngwaọrụ.

ovadozu

Ibu ụzọ na-akpọ gag mpiaji ma ọ bụ afo-na-asa na ihe ovadozu nke ọgwụ "Hydroxyzine". Ntuziaka maka ojiji na-agwa na n'ọnọdụ ụfọdụ ọ dị mkpa nlekota ọrịa dị mkpa ọrụ, iwebata sodium benzoate, caffeine, nọrepinefrini, na ọbụna ọbara nọ n'ọnọdụ, na-rụrụ niile dị mkpa jikoro ịnọgide na-enwe kwesịrị ekwesị ịrụ ọrụ nke ahu. Specific mgbochi ngwá ọrụ nwere, hemodialysis na-adịghị n'onye ezi omume.

Ọtụtụ mgbe, ihe ndị a na-reversible ma ọ bụ ha mgbaàmà akwụsị mgbe a kwa ụbọchị onunu ogwu nke idegharị.

Ọnụọgụ ọgwụ

The ọgwụ na-ndinọ ọnụ ma ọ bụ site na intramuscular ogwu ogbugba. The dose adabere nosologies, afọ nke onye ọrịa ahụ na ụdị nke na-ọgwụ a tọhapụrụ "Hydroxyzine".

Ntuziaka maka ojiji na-egosi na symptomatic ọgwụgwọ maka nchegbu syndrome, okenye na-atụ aro oriri nke 25 ruo 100 mg nke constituent umi n'ụbọchị. Ndị akacha eji usoro onunu ogwu nke 12.5 mg ụtụtụ na na nri ehihie na 25 - na mgbede.
Na nwata, preoperatively-eji 1 mg kwa n'arọ nke ahu arọ na mgbede ụbọchị tupu na 60 nkeji tupu usoro.

N'ihi nzube nke premedication na-ndinọ okenye "Hydroxyzine" na a dose nke 50-200 mg nke ọgwụ ọnụ ma ọ bụ n'ụdị intramuscular injections nke 1.5-2.5 mg kwa n'arọ nke ndidi ibu ndinọ otu awa tupu ịwa ahụ.

N'ihi nzube nke enyemaka nke itching irè onunu ogwu bụ site 25 ruo 100 mg na 3-4 ekewa doses.

Children si otu afọ 6 afọ ndị dose adịghị gafere 1-2.5 mg kwa n'arọ nke ahu arọ kwa ụbọchị na kewara doses.

N'otu dosing Usoro maka ụmụaka n'okpuru afọ 6 afọ na e kenyere ya 1-2 mg kwa n'arọ nke ahu aro n'ụbọchị.

Oke kwa ụbọchị dose-atụle ga-300 mg. Oke otu dose - 200 mg.

Agadi nnabata nke ọgwụ na-atụ aro na ọkara onunu ogwu.

Imeju na-na akụrụ odida achọ mgbazi nke onunu ogwu nke ọgwụ ọjọọ, "Hydroxyzine".

Guide adọ aka ná ntị na na nweta kacha ọgwụgwọ mmetụta ngwa ngwọta na-ndinọ intramuscularly, miri 50-100 mg kwa otu dose. Ọ na-atụ aro iji ọgwụ ochichi usoro maka 4-6 awa.

Na uche, na nkà mmụta ọgwụ na-etinyere na a onunu ogwu nke 300 mg maka ụbọchị. Na oge nke a ọgwụgwọ bụ 4 izu.

Bụrụ na nke na-egosi na mmetụta ndị dị otú ahụ dị ka adịghị ike, iro ụra, anaghị akwụsị n'ime ụbọchị ole na ole, ndị dose ga-belata.

precautionary jikoro

Mgbe iwebata "Hydroxyzine" si "adrenaline" adịru obere irè.

The ọgwụ nwere a nwee ume utịp ke ogwuura mmetụta nke narcotic analgesics series, na-aba n'anya, ọgwụ na-akụjụ, barbiturates, ọgwụ ọjọọ eme ihe na ebumnuche nke na hypnotic na ndị ọzọ ọgwụ ọjọọ eme ihe ndị ga-akụda CNS ọrụ.

Ọ bụghị na-atụ aro na nkwonkwo ngwa nke umi ma ọ bụ holinoblokatorami na Mao inhibitors.

Mgbe jikọtara na n'aka-ewere phenytoin anticonvulsant mmetụta mbelata si n'ikuku nke ikpeazụ.

Ekwesighi imekotaotuugbo ngwa nke ọgwụ na cholinesterase blockers.

A na-esi na-amụba plasma ịta nke ọgwụ nwere ike na-eje ozi ya ngwa na inhibitors nke imeju enzymes.

Imekotaotuugbo ọgwụgwọ na mmadụ nke inhibit ọrụ nke CNS, ma ọ bụ na holinoblokatorami achọ onunu ogwu ukpụhọde.

Na oke-elekọta ga-kenyere ka ọrịa na-enwe a propensity maka fibrillation ma ọ bụ itinye antiarrhythmics, nakwa dị ka ndị ọrịa a na-predisposed ka convulsive n'obiọma. The ọgwụ bụ a contraindication ka mmanya na-aba n'anya. Ọ bụrụ na ọ dị mkpa, na omume ule na allergies n'ikuku "Hydroxyzine" iji kagbuo ruo 5 ụbọchị tupu ndokwa nyochaa. Dị mkpa ịkpachapụ anya iji ọgwụ ọjọọ na a ụgbọala akara mgbe ọkwọ ụgbọala na ndị ọrịa, Ọrụ na-achọ elu ịta.

Ọ ga-iburu n'uche na ihe injectables bụ nanị kwe omume site na intramuscular ogwu ogbugba. Subcutaneous ntụtụ ụgbọala ma ọ bụ penetration nke ikpeazụ na nnukwu arịa nwere ike ime ka anụ ahụ mebiri.

Agwọ ngwá ọrụ a nwere ike vyzyvavt ụgha pụta prick ule.

Usoro na ọnọdụ nke were na nchekwa

Ọ dị mkpa ka ndị obligatory ọnụnọ nke a ọgwụ maka ọgwụ "Hydroxyzine".

Ntuziaka maka ojiji na-ekwu na ọnụ na forms nke ọgwụ na-adịghị echekwara n'ihi na ihe karịrị 5 afọ.

"Hydroxyzine". nleba

Na ụmụ, na ojiji nke ego n'okpuru hyperactivity, belata uche n'ihe na-enyere nwa na-enwe obi ike, lekwasịrị anya na enyịn, eliminates ọnọdụ swings. N'otu oge ahụ na ọgwụgwọ nke ọgwụ ọjọọ, "Atarax" ( "Hydroxyzine") ntuziaka maka ojiji obi sie na-arụ ọrụ na vitality nke nwa-anọgide na otu. Mmetụta dị ụkọ.

Dị ka okwu nke ọrịa, itinye ụfọdụ ikpe "Hydroxyzine" (analogues nke ọgwụ), ọ pụtara na ọ bụ nwayọọ na onwe-obi ike ka ukwuu karịa ọtụtụ ndị ọzọ ọgwụ ọjọọ. Panic ọgụ na ehighị ụra nke ọma na umi-akwalite mma ụra na a ụda ụra. Otú ọ dị, mwepụ nke ọgwụ mbụ ụbọchị ole na ole nke oké ọnụ ọgụgụ na usoro nke ụra, ma, ụkpụrụ, mmetụta nke ọgwụ bụ nnọọ ume.

The price nke ọgwụ

Ịzụta ọgwụ "Hydroxyzine" ogbo, dị ka akụkụ nke nke nwere hydroxyzine, ike a na-ere ọgwụ na ndenye ọgwụ. Price bụ 270-300 rubles kwa 25 mbadamba 25 mg.

"Hydroxyzine". Synonyms

Synonyms of "Hydroxyzine" bụ: "Hydroxyzine Canon", "Atarax", "Masmoram", "Ateraks", "Hydroxyzine", "Hydroxyzine Hydrochloride", "Alamon", "Duraks".