The ọgwụ 'Manini': ntuziaka maka ojiji

Nkwadebe "Mannino" ntụziaka ntuziaka na-akọwa dị ka irè antidiabetic ọgwụ na ndekọ njem (International Nonproprietary Names) aha bụ "Glibenclamide". Nke a na umi bụ isi ike na a nkwadebe, nke na-emepụta site emepụta n'ụdị mbadamba, erikpu 1,75 mg ma ọ bụ 3.5 mg. The ọgwụ mejupụtara inyeaka ogige na-agụnye lactose monohydrate, silica, nri mmako E 124 - cochineal e ji esiji ákwà, nduku starch, gimetelloza.

The pharmacokinetic Njirimara nke ọgwụ bụrụhaala na glibenclamide - Isi nọ n'ọrụ umi - na ẹdude ke Nwa na micronized ụdị. Nke a na-eme ka o kwe omume ka iwelie penetration ọnụego nke ọgwụ na-amụba n'ógbè ya mmiri. Ọzọkwa, ndị ọzọ dị irè absorption nke ọgwụ mmiri na-eme methylhydroxyethylcellulose, nke bụ akụkụ nke nkwadebe "Mannino".

Ntuziaka maka ojiji ga-agwa na mmako nwere ọ nweghị mmetụta na ala nke aru, ma, o sina dị, na-eme ka o kwe omume na ezi budata dịkwuo obibi oge nke mmiri nke ọgwụ na chụsasịrị achụsasị adọ, ndị kasị arụpụta maka omume ya. N'oge a na-adọ ịta nke ọgwụ na plasma mmiri enwekwu atọ na ise mgbe, otú ahụ ka a bụ a ukwuu Mbelata ke ego nke glucose.

Agwọ ọrịa "Mannino" ihe e ji mara ma ndu pụtara na-enwe na ihe onwunwe ngwa ngwa etinye obi gị dum na eriri afọ tract na ya micronized ụdị glibenclamide enyere kpam kpam tọhapụrụ site inyeaka ogige ke idem maka nkeji ise. Nke a pụrụ isi kwuo ya na-eme ka o kwe omume na-ọgwụ tupu a nri, maka 5 - 10 nkeji tupu. Ọnụ ọgụgụ kasị elu ịta emee mbụ nkwadebe, na ya eme ihe, ya mere, ọ bụ n'ahụ. Ọ bụ ezie na ụkpụrụ, nke imekotaotuugbo n'ikuku nri enweghị ọtụtụ utịp ke edinam nke ọgwụ. Nkwadebe "Mannino" nwere a larịị nke 100% bioavailability. Ya ọkara ndụ-nke ahụ organism bụ nkezi nke otu na ọkara atọ na ọkara awa.

Oge mụ hypoglycemic mmetụta nke glibenclamide na-nọgidere na-enwe ihe n'ụbọchị ahụ.

The pharmacodynamic Njirimara nke ọgwụ, "Manini" ntụziaka ntuziaka na-akọwa na nke a ụzọ. Medikamet Nke a nwere ike melite secretion nke insulin mgbe mmiri si beta sel nke pancreas, na ọgwụ enhances insulin uche, nke na-enweta site mmalite nke insulin ihe nnabata.

Ọzọkwa, glibenclamide bụ ike belata ihe nke platelet gbochie myocardial ischemia. The ọgwụ na-nwere a mgbochi ihe megide gbasara obi arrhythmias.

Dị ka na-ọma ike, ọgwụ si otú mbenata ihe ize ndụ nke nsogbu nke ọrịa shuga (ụdị 2), nke na-agụnye ọrịa cardiomyopathy, nephropathy na retinopathy. Medicine "Mannino" ntụziaka ntuziaka na-akọwa ihe dị ka ụzọ nke mbenata larịị nke na enwe na ọrịa metụtara na-arịa ọrịa shuga.

Isi na-egosi maka ojiji nke glibenclamide - arịa ọrịa shuga nke abụọ ụdị, mgbe nri ọgwụ gosiri ihe unsatisfactory pụta. Mbadamba "Manin" nwere ike ji mee ka otu nọọrọ onwe ha ọgwụgwọ gị n'ụlọnga, na dị ka akụkụ nke Nchikota ọgwụ ndị ọzọ na-emegide ọrịa ọgwụ.

Ọ ga-iburu n'uche na oge nke ọgwụ na dose of uru kpebisiri ike site dibịa dabeere na onye obibia ka onye ọrịa. Mgbe mbụ ogbo nke ọgwụgwọ ka nta doses nke ọgwụ ochichi. Mgbe ahụ, a mgbazi mode nke ngwa, ọnụ na mgbazi nke nri. Nkọwa nke dose Usoro a kọwara na ntuziaka maka ojiji nke ọgwụ.

The isi criterion maka dose ukpụhọde bụ larịị nke glucose.

Ịnata glibenclamide nwere ike ime ka mmetụta, na ọtụtụ nkịtị nke bụ hypoglycemia. Ya mgbaàmà bụ mberede sweating, tremor, isi ọwụwa, akwara ozi ọgba aghara, na ndị ọzọ.

Contraindications maka ochichi nke ọgwụ na-hypersensitivity na mmiri inefficiencies abụọ ọgwụgwọ na "Mannino", ketoacidosis, ọtọ ọrịa nke akụrụ na imeju.

E nwere ezughị ọmụma na nke ọgwụ umu, onye afọ adịghị gafere 18 afọ.

Ị na-eji ọgwụ n'oge ara na n'oge ime.

Echekwa ọgwụ ga-abụ na a okpomọkụ nke bụghị ihe karịrị 25 C. Na ọnọdụ nchekwa adị ndụ nke ọgwụ bụ 3 afọ.