Bismuth tripotassium dicitratobismuthate - antiulcer gị n'ụlọnga

Bismuth tripotassium dicitratobismuthate (tradename - ọgwụ ọjọọ, "De-Nol") bụ irè mgbochi ọnyá afọ ọgwụ na-enwe a akpọ bactericidal ọrụ megide microorganisms nke umu Helicobacter pylori. Ke adianade do, a ọgwụ nwere antacid, antiinflammatory na astringent mmetụta. Ịnata na nke a pụtara ọtụtụ ugboro mma na-echebe e ji mara eriri afọ mucosal elu, na-akpụ a pụrụ iche unyi anaghị agbasa na mkpuchi na na saịtị nke ọnyá afọ. Ọzọkwa bismuth tripotassium dicitratobismuthate enwekwu kwụsie ike envelopu afo na eriri afọ na mmetụta ọjọọ nke enzymes pepsin na hydrochloric acid enwekwu imi mmepụta, secretion nke bicarbonate na prostaglandin njikọ nke ụdị E. Ke adianade niile nke dị n'elu, ọkachamara na-ekwu ya ike na-akpali ọrụ nke cytoprotective usoro.

Ma ihe ndị pharmacokinetics nke mgbochi-ọnyá gị n'ụlọnga, mgbe ahụ, dị ka a N'ihi nke a N'ezie nke ịha ịta n'ime ọbara na-ruru mgbe anọ ise ụbọchị na ọkara ndụ-nke banyere ụbọchị ise. Na nke a, na-arụsi ọrụ ike akụrụngwa na-kpamkpam anyụpụ si ahụ nanị mgbe iri na abụọ izu mgbe mmalite nke n'ikuku nke a ngwá ọrụ ndị dị otú ahụ dị ka bismuth tripotassium dicitratobismuthate. Analogs nke ngwá ọrụ - ọgwụ "Bismay" "Desmol" na "Novobismol" - nwere otu usoro nke edinam.

Nke a na-emepụta ihe antiulcer ọgwụ tumadi n'ụdị ot ọgwụ dragees ntekwasa. Were Erere "De-Nol" (bismuth tripotassium dicitratobismuthate), onye price bụ nnọọ oké ọnụ, ndị na-emepụta na-atụ aro nanị maka ọgwụgwọ nke ọnyá afọ 12 duodenal ọnyá afọ ma ọ bụ na afo. Ndị na-enwe-adịghị ala ala mgbu ga-amalite mgbe nile na-ewere nke a ọgwụ. Ke adianade do, bismuth tripotassium dicitratobismuthate ngwa enyemaka bụrụ na nke dyspepsia, na-abụghị organic eriri afọ ọrịa.

Were mgbochi ọnyá afọ ọgwụ dọkịta haa machibido oké gbasara akụrụ dysfunction, nakwa dị ka n'oge ime. Mụbara uche na ya ara oge nke nwa ọhụrụ n'otu aka ahụ, esịne ke ndepụta na nlezianya contraindications. Ọrịa ndị na-eru afọ iri na abụọ, na-ekwesịghị amalite na-ewere ọgwụ, nke na-agụnye bismuth tripotassium dicitratobismuthate. Ke adianade do, ị kwesịrị ị na mgbe niile na-n'uche na ndị mmadụ dị iche iche na iche iche nke nwere nkwarụ na-arụ ọrụ nke akụrụ dị ka a n'ihi nke ruo ogologo oge iwere nke elu doses nke a gị n'ụlọnga nwere ike ịzụlite encephalopathy.

Ọ bụrụ na anyị na-atụle ihe ndị kasị oghom Jeremaya mere, omume nke nke nwere ike mere site n'ikuku nke antiulcer ọgwụ, ọ bụ n'ụzọ bụ isi dị mkpa ka igbunye vomiting, ọgbụgbọ na afọ ọsịsa. Ke adianade do, e nwere a pụtara elu n'ihe ize ndụ nke anụ ọkụ ọkụ, itching, nācha ọbara-ọbara nke anụ ahụ na angioedema.