"Co-Perineva": analọg. "Co-Perineva": ntuziaka maka ojiji, n'ezie na

Site ọbara mgbali ugbu a na-ata ahụhụ zuru ezu sara mbara n'ígwé nke ndị bi na nke dị iche iche na-elekọta mmadụ àgwà, ego, larịị nke muta. Ma ọ bụ anyị nwere ike ikwu na a na ọrịa na-na mesịa ndị agadi, dị ka ọ bụ, sịnụ, na narị afọ gara aga. Modern ndụ bụ ngwa, zuru ụwa ọnụ nsogbu, elu technology, ọchịchọ ime ka o kwere mee taa na echi na-eme ihe, ekwela ka nke ahụ n'ụzọ zuru ezu zuru ike. Na ọnọdụ nke mgbe nile nchegbu na-arụ ọrụ n'ụlọ ịgba nke anụ ahụ ike na-emepe emepe ọbara mgbali. Onye nke oge a na ndị mmadụ ntị ka eziokwu ahụ bụ na ọ bụ mgbe a isi ọwụwa? Akpịrị a ụbọchị ma ọ bụ abụọ, a izu, a ọnwa, na mgbe, n'ikpeazụ, onye na-aga a na dọkịta, na mgbe ọ na-aghọ doro anya na ọbara mgbali kemgbe ebe na-adị.

Nkà mmụta ọgwụ ọgbara ike na-enye ibu hypertensive ọgwụ akawanye ọbara mgbali, otu onye nke bụ "Ko Perineva". Ntuziaka maka ojiji e dere ihe ọmụma zuru ezu banyere ohere, contraindications na mmetụta.

Structure na mejupụtara

Isi ifịk ifịk mmiri nke agwọ ọrịa na-indapamide na perindopril erbumine. Ọzọkwa, mbadamba Ọzọkwa ugbu semifinished ngwaahịa nsogbu dị iche iche (dị ka crospovidone, lactose monohydrate na calcium chloride hexahydrate), na ọtụtụ inyeaka bekee.

Ụdị nke ọgwụ ntọhapụ - gburugburu biconvex ọcha mbadamba. Nyere na ọtụtụ Dosages. Na asịwo ike ịzụta si pharmacies agwọ ọrịa-arụ ọrụ bekee +2 dose of 0,625 mg, karị, 1.25 + 2.5 + 4 ma ọ bụ 8 mg.

Ke ofụri ofụri, m ga-asị na ndị French dọkịta mepụtara na ihe ịga nke ọma na-eji ọgwụ ọjọọ, "Noliprel A" ya, na Russian counterpart - "Co-Perineva".

pharmacodynamics

Perindopril bụ ihe Ace inhibitor, ọ na-akwalite vasodilatation, si otú mbenata ọbara mgbali na ya, ibu na-adịghị ebelata obi. Mgbe 4-6 awa mgbe na-anata agwọ ọrịa amalite karịa mmetụta nwere ike nọgidere na-enwe ihe n'ụbọchị ahụ. Indapamide bụ ìgwè nke diuretics thiazide diuretics. Ọzọkwa, a na umi nwere ike melite ekwedo nke vaskụla mgbidi, nke nwekwara-eme ka Mbelata ke ọbara mgbali.

Olee otú ọ bụla nke ya counterpart, "Co-Perineva" enweghị mmetụta na Filiks nke abụba na carbohydrate metabolism. Ọzọkwa, ọnụnọ nke indapamide adịghị akpata ọtụtụ nsogbu na mmiri nnu itule nke ahụ ahụ, nke nwere ike ghara kwuru nke ọzọ mamịrị ọgwụ. Ọgwụgwọ na a Nchikota pụtara ( "Co-Perineva") anaghị akwalite tachycardia, akawanye ala nke gbasara obi muscle, rụọ ọrụ ya ike na-ebu ibu nke ya.

Ònye kwesịrị izere itinye?

Ọgwụ dị irè maka ọgwụgwọ nke ọbara mgbali elu, Otú ọ dị, ọ na-nwere a ndepụta contraindications. "Co-Perineva" analogs enwe a akụkụ nke otu n'ọrụ Efrata na-ekwesịghị iwere ka ndị na-hypersensitive ọ bụla mmiri nke nkwadebe. Ma ọ bụ na-kenyere ọgwụ ndị na-ata ahụhụ ekweghị ibe nọrọ ma ọ bụ lactose erughi, glucose-galactose malabsorption, gbasara akụrụ akwara stenosis, hepatic ma ọ bụ gbasara akụrụ insufficiency. Contraindication maka ojiji nke "Co-Perineva" bụ ọnụnọ a ndidi refractory hyperkalemia (potassium ngafe ke idem), a pụrụ ịrịa mmepe nke angioneurotic edema (mmeghachi omume na mmetụta nke chemical na ndu elekọta mmadụ, ọ bụ nke ukwuu mgbe ndị anabata uwa).

Ekwela inye "Co-Perineva" na ndị ọrịa na-ata ahụhụ azotemia (ọbara n'elu ókè nwere nitrogen metabolism ngwaahịa nke a ga-egosipụta na akụrụ) na anuria (mmamịrị anaghị igba n'ime eriri afo). Guzobere na nrụpụta na nchekwa nke "Co-Perineva" (yiri ọgwụ ọjọọ nwere ike na-eji na ọnụnọ nke na-adakarị ọnwụnwa) na ọrịa tọrọ afọ 18, ime, lactating inyom. Ya mere, n'ihi na ndị a iche iche nke ndị na-ewere ọgwụ na-aju.

Ekwe Omume mmetụta

The kasị oghom mmetụta nke nwere ike ime ka ndị agwọ ọrịa ma ọ bụ ọnụ ala analogue "Ko Perineva" - mbadamba "Perindopril plus Indapamide" - a pụrụ ịkpọ ụfọdụ oghom ihe si dị iche iche na akụkụ na aru na usoro. Ndị kasị Ugboro Jeremaya mere nke Central ụjọ usoro bụ isi ọwụwa, dizziness, adịghị ike, sensory ọnwụ. Site uche ziri ezi, i nwere ike ịnụ mkpọtụ na nti nke visual uzọ. Omume ya ọnụ ke ọbara mgbali - ekwe omume mmeghachi omume nke obi usoro.

Akọrọ, iwe, na-abụghị na-arụpụta ụkwara na-egosi a akụkụ okuku ume na mmeghachi omume. A nnukwu iji ndepụta deviations pụrụ hụrụ na nke eriri afọ tract. Ebe a, na-akwanyere omume ọgwụ "Co-Perineva" (analogues) reviews ndidi okwu banyere ọgbụgbọ, vomiting, afọ ọsịsa, Ugboro afọ ntachi, abdominal mgbu na epigastric, mgbanwe nke uto, ebelata agụụ. Nweekwa usoro nwere ike na-echetara onwe gị cramps.

Dị iche iche na mmetụta ndị dị otú ahụ dị ka akpụkpọ ọkụ ọkụ ná mgbanwe nke osisi ike, pruritus, ọdịdị ihu edema, mucous membranes nke onu uji eze, okpo ọnụ ma ọ bụ ire elu nkọlọ.

dosing Usoro

The onunu ogwu nke agwọ ọrịa (ma analogue "Ko Perineva" nwere ike natara site ọzọ circuit) - otu mbadamba n'ụbọchị. Nke a na-kacha mma mere nke ụtụtụ, tupu nri ụtụtụ, na-aṅụ mmiri. Na ọtụtụ ndị mepere emepe atụmatụ nke ịgbakọ ruru "indapamide / perindopril". Akpa, ndị ọrịa na-ndinọ mbadamba na a onunu ogwu nke 0.625 / 2 mg. Ọ bụrụ na mgbe a ọnwa iji nweta akara nke ọbara mgbali bụ ekwe omume, na-dose na-ụba na onye mbadamba na a dose nke 1,25 / 4 mg. Iji nweta irè results, na onunu ogwu nwere ike ụba na a kacha kwa ụbọchị - 2,5 / 8 mg.

Agadi ọrịa amalite ọgwụgwọ na otu mbadamba na a onunu ogwu nke 0.625 / 2 mg. The ọgwụ na-amalite na na-ekenịmde n'okpuru mgbe nile akara nke ọbara mgbali na akụrụ ọrụ.

Ọ bụrụ na onye ọrịa na-ata ahụhụ site na gbasara akụrụ odida na-agafeghị oke ókè, ọgwụ na-amalite na onunu ogwu nke 0.625 / 2 mg, ma na kacha allowable maka a ụbọchị dose ekwesịghị gafere 1.25 / 4 mg.

Oké doses: mgbaàmà, ọgwụgwọ

Mgbaàmà nke ịṅụfe ọgwụ ike ókè nke ọgwụ mere bụ ọnụnọ nke ọgbụgbọ, vomiting, muscle cramps ịzụlite. E nwere iro ụra, dizziness, mgbagwoju anya, oliguria (mmamịrị olu Mbelata, akụrụ), iju ke ọmụmụ na electrolyte itule, ọbara mgbali dobe. Ọ bụla analọg nke "Co-Perineva" nwere mgbaàmà ndị ọzọ ịṅụfe ọgwụ ike ókè.

Iji kpochapụ mmetụta nke na-atụ aro gastric lavage na n'ikuku nke absorbent ngwaahịa. Ọ dịkwa mkpa iji weghachi mmiri na electrolyte itule. Ọ bụrụ na e a nkọ dobe na ọbara mgbali, ọrịa ga-edina gị azụ, na-azụ ụkwụ. The ịga dibịa nwere ike na-atụle ya dị mkpa ịme 0,9% sodium chloride ngwọta. E nwere ozi na irè nke hemodialysis.

Ime na lactating inyom

"Co-Perineva" ntụziaka ntuziaka machibidoro ụmụ nwaanyị dị ime na nwa ara na nne. The eji nke a ọgwụ n'oge gestation nwa nwere ike ịkpalite mmepe nke placental ischemia, na dị ka a na ya pụta, na-amụba ihe ize ndụ nke nwa ebu n'afọ na ibu iberibe. Ọ bụrụ na anyị na-ekwu okwu banyere a na-azụ nwa, ị kwesịrị ị na-n'uche na indapamide ọ na-anyụpụ na mmiri ara. Ọ bụrụ na Otú ọ dị, ojiji nke "Co-Perineva" lactation - mkpa ga-enye elu ara.

Special ntuziaka

Jiri nke unacceptably "Ko Perineva" ke ukem ọ bụla ọgwụ lithium. Mgbe Abuse akụrụ arụ ọrụ dị ka a agwọ ọrịa kwesịghị ịnabata. Ọ bụrụ na onye ọrịa na-chọpụtara na ọbara mgbali n'oge ọgwụgwọ pụtara "Co-Perineva" pụtara akụrụ odida mgbaàmà, ọgwụgwọ ga-akwụsị ozugbo. A obere ka e mesịrị, i nwere ike na-agbalị ịmaliteghachi na-ewere ọgwụ na nke kasị ala dose ma ọ bụ ịgbanwee monotherapy na indapamide na perindopril. Na ndị dị otú ahụ ọrịa ọ bụla 2 izu dị mkpa iji nyochaa larịị nke potassium na creatine ke iyịp.

Na ọrịa na-arịa ọrịa shuga mellitus ma ọ bụ gbasara akụrụ odida "Co-Perineva" (gụnyere analogs) nwere ike ime ka hypokalemia development. Ya mere, dị ndị mmadụ mkpa mgbe nile nlekota nke larịị nke potassium ke iyịp.

Mmekọrịta ndị ọzọ bekee

Unu na-eji perindopril ọnụ na potassium-ịhapụ mamịrị ọgwụ ọjọọ na potassium. Ọzọkwa na elu ịkpachara anya agwọ ọrịa onwe ya (na ihe ọ bụla analọg ọgwụ ọjọọ "Ko Perineva") ndinọ na insulin ma ọ bụ ndị ọzọ hypoglycemic mmadụ. Co-ochichi nke ọgwụ na cytotoxic immunosuppressive ọgwụ ọjọọ nwere ike ime ka mmepe nke leukopenia. Iji ọgwụ ọjọọ eme ihe na ọgwụ maka general ná Nkụnwụ yiri ka dịkwuo hypotensive mmetụta.

Indapamidsoderzhaschie ọgwụ kenyere na-elekọta ke ukem na neuroleptics na antiarrhythmics, benzamide buterofenonami. Ọzọkwa, "Ko Pireneva" na-adịghị eme ndinọ ọgwụ ọjọọ nke nwere ike ịkpasu hypokalaemia mmepe na-laxatives, stimulant ngiri-afọ.

The ojiji nke dị iche mmadụ na a elu ọdịnaya nke ayodiin nwere ike inye ihe kwalite mmepe nke gbasara akụrụ odida.

ọgwụ analogues

Ndị akacha eji na a maara n'etiti ndị ahịa analogue "Co-Perineva" - "Noliprel A". Onunu ogwu (ruru "perindopril / indapamide" si mbụ na-emeputa "Servier" France) nwere ike ịbụ 2,5 / 0.625 mg, 10 / 2,5 mg, 5 / 1.25 mg. Ọzọkwa, a ọgwụ na-emepụta na Russian Federation ( "Serdiks") na otu onunu ogwu dị ka ihe mbụ.

Ọzọ maara nke ọma yiri ọgwụ - "Perindopril plus indapamide" si Russian emeputa. N'ihi na n'elu oke kwere omume onunu ogwu nke 1.25 / 4 mg, 2,5 / 0.008 mg, 0.625 / 0.002 mg, 8 / 2.5 mg.

price nso

The onunu ogwu na ọnụ ọgụgụ nke mbadamba a ngwugwu - na isi ihe na-emetụta ndị price nke ọgwụ, "Ko Perineva". Ntuziaka (analogs nwere ike iche ubé na onunu ogwu) na-akọwa na nhọrọ maka mmekọahụ nke abụọ isi mmiri - perindopril na indapamide. Dị ka ihe atụ, a mbadamba 30 na a ruru nke 0.625 / 2 mg eri asịwo 350 rubles. The ọgwụ na a onunu ogwu nke 1.25 / 4 mg ga-eri 390-440 rubles. The kasị ibu ruru nke 2.5 / 8 mg - 470 na 510 rubles 30 mbadamba. N'ezie, ngwungwu 90 mbadamba ga-eri na-azụ ahịa a nnọọ elu ego.

French mbụ "Noliprel A" na-eri na-eji ọkụ a ọtụtụ ihe dị oké ọnụ.

n'ji uche

Agwọ ọrịa "Co-Perineva 'ntuziaka maka ojiji, ndidi nzaghachi, ọtụtụ mgbe, e ji dị ka a n'oge a na nnọọ irè ọgwụ ka normalize ọbara mgbali. The ọgwụ dị mfe iji: ewe otu mbadamba-ututu, ma bụ free ruo echi. Ke adianade do, ndị na-eri na "Co-Perineva" inweta a dịgasị iche iche nke ahịa na dị iche iche ego ike, nwere ike ghara kwuru banyere "Noliprel A" si French emeputa.

Otú ọ dị, ọ bụghị ihe ọhụrụ, na-ezighị ezi nzaghachi, nke a na ọtụtụ-ejikọta ya na ọdịdị mmetụta n'ụdị isi ọwụwa, ọzịza nke ihu na nsọtụ, Jeremaya si eriri afọ tract. N'ọnọdụ dị otú ahụ, kwụsị ọgwụgwọ na ịkpọ onye dọkịta. Mgbe nnyocha na nwale ọkachamara ga-ekpebi ma maliteghachi ewere ọgwụ, "Ko Perineva" na a belatara dose, ma ọ bụ mma-aṅa ntị ọgwụ ndị ọzọ na yiri e ji mara na ndị na-atụ anya ihe omume.