"Nimid" (mbadamba): Ntuziaka maka ojiji na nzaghachi

Ndị na-enwe ọrịa nke ọkpụkpụ, nkwonkwo na akwara dị ka a symptomatic ọgwụgwọ dọkịta mgbe idepụta "Nimid" (mbadamba). Ntuziaka maka ojiji e dere ozi na ọgwụ ọ bụghị nanị na-ewepụ ihe mgbu, ma na-nwere mgbochi mkpali edinam. Ka anyị na-agbalị na-enyocha arụmọrụ nke ngwaahịa na ihe nkowa na chọpụta na nke ikpe na o nwere ike inyere ya aka.

Drug ụdị na mejupụtara

Banyere forms nke ọgwụ, mgbe ahụ taa na pharmacies pụrụ ịzụta a mbadamba, a nkwusioru, nsogbu dị iche iche na jel. Isi nọ n'ọrụ mgwa ha bụ nimesulide. Tablet Nwa nke ọgwụ wepụtara na 10 mbak blisters. Otu mbadamba dere 100 mg nke nimesulide, na dị ka inyeaka mmiri eji pharmacists microcrystalline cellulose, sodium stearate, croscarmellose sodium na Aerosil 200. Nke nwere ihe ọmụma dị otú banyere ihe ndị mejupụtara "Nimid" nkwadebe (mbadamba) ntuziaka maka ojiji.

Na ntụ ntụ na-emepụta a dose sachets. Nke a na ụdị ọgwụ bara uru maka ọgwụgwọ nke ụmụ. N'ezie, na ihe ndị mejupụtara, ma e wezụga nimesulide, povidone K-30, tabletozy 80 na Aerosil 200 nwere excipients dị ka sodium saccharin, citric acid, na flavorings. Ụkọ obi ụtọ na-aṅụ a na-atọ ụtọ esie nne na nna ya ọgwụgwọ "mmanya".

Na 1 ml nke nkwusioru, na 1 g nke jel dere 100 mg nke nimesulide. Dị ka ihe inyeaka akụrụngwa na abụọ ndị a iche-iche eji propylene glycol, sodium gidroskid, carbomer 940, disodium edelat, aromotizator, ọcha mmiri na methylparaben.

The pharmacological edinam nke ọgwụ

Nimesulide, nke bụ n'ọrụ mgwa nke agwọ ọrịa bụ ìgwè nke ndị so ná ndị na-emegide sulfonanilides. Ozugbo ahụ mmadụ, ya bibiri egbochi Cox-2 na-egbochi njikọ nke prostaglandins na mkpali locus. Ịnụ ọgwụ, antipyretic na mgbochi mkpali mmetụta a na-enweta mgbe a otu "Nimid" mbadamba. Ntuziaka maka ojiji nwere ihe ọmụma banyere usoro onunu ogwu ọgwụ.

Na mgbakwunye na n'elu, ọgwụ bụ ike inhibit ntọhapụ nke oxygen free radicals na inhibit ntọhapụ nke myeloperoxidase, na-enweghị mmetụta na chemotaxis na phagocytosis Filiks.

Ma ihe ndị mgbochi mkpali edinam nke ọgwụ, ọ na-enweta site nimesulide ike ibelata ihe mgbu ogbugbo ma belata akpụ necrosis ihe. Site inhibiting njikọ nke interleukin-6 na urokinase nkwadebe "Nimid" (ntụziaka ntuziaka na-akwado eziokwu a) egbochi Ihere proteoglycans na collagen cartilage. Ke adianade do, nimesulide ejide nkanka maka nociceptive mgbu gboo usoro.

Ọ bụrụ na anyị na-atụle usoro nke ịnụ ọgwụ eme ihe, a na-ejikọta ya na mgbochi nke histamine ntọhapụ usoro nke ọtụtụ poolu mkpụrụ ndụ na mmetụta nke nọ n'ọrụ compound kwa glucocorticosteroid anabata.

Ọ bụrụ na dọkịta gị edepụtaraghị "Nimid" (mbadamba), na ntuziaka maka ojiji a ga-akpachara anya na-ewere tupu ewere ọgwụ. Mgbe niile, akwụkwọ a nwere na-atụ aro na a ga-sonye na akaụntụ n'oge ọ na ọgwụ.

Pharmacokinetics

Mgbe na-anata na-atụ aro dose nke ọgwụ na-arụsi ọrụ etinye obi gị dum na eriri afọ tract. Na mgbe 1.5-2.5 awa gosiri kacha ịta nke nọ n'ọrụ mgwa n'ime ọbara plasma. A mara mma nke nkwadebe bụ elu ike na-emekọ ihe na-edozi, nakwa dị ka ndị penetration nke ọbara ụbụrụ mgbochi na gematoplatsentarny. Na elu kasịnụ nke nimesulide kpebisiri ike na a locus nke mbufụt, na synovial ọmụmụ.

ọgwụ metabolism pụtara na imeju, wdg, n'ihi na ọtụtụ akụkụ na-agbanweghi agbanwe ụdị ifịk metabolites, tutu amama site akụrụ (na mmamịrị), na - na faeces. The ọkara ndụ-nke nọ n'ọrụ umi a na-enweta site na 3.5-5 awa. Ọ nwere ihe kpọmkwem pharmacokinetic data "Nimid" nkwadebe ntuziaka maka ojiji.

na-agba akaebe

Ọma agwọ ọrịa maka fever na-eso nke ọrịa na nke elu akụkụ okuku ume na tract na elu akụkụ okuku ume na tract. Ọtụtụ mgbe nye iwu a ọgwụ maka ndị mmadụ na-ata ahụhụ si na ọrịa ogbu ogbu na nkwonkwo, myalgia, osteoarthritis, bursitis, tendonitis, na ndị ọzọ na muscle ọrịa, ọkpụkpụ na nkwonkwo, Bilie mgbu syndrome. Na eze na gynecological omume maka postoperative mgbu na postrevmaticheskih na-eji "Nimid" agwọ ọrịa. Ntuziaka maka ojiji dị otú ahụ ikpe ọ bụ ihe amamihe na-azụta a mbadamba, ntụ ntụ ma ọ nsogbu dị iche iche.

Na-akwanyere ndị ọgwụ ọjọọ na jel ụdị, na ọ na-zubere maka Nde eji na ire ọkụ ka anụ ahụ (soft) nke na-akpata dị iche iche mkpasasị uche. Ọma pụtara na-na mkpali Filiks na degenerative ọrịa nke nweekwa usoro, osteoarthritis, ankylosing spondylitis , na ndị ọzọ. Ọ na-nwere ihe na-amụba ndepụta egosi maka ojiji nke ego "Nimid" ntuziaka maka ojiji si emeputa.

N'ikuku na ọnọdụ na dosing usoro

Mgbe ọ na-abịa na-ewere ọgwụ ọjọọ na ụdị mbadamba, suspensions, ọ dị mkpa na-eji ya nanị mgbe a nri. Ọ na-achọsi ike ka agafeela dịkarịa ala, 20 nkeji mgbe ingestion, ma pharmacokinetic mmetụta nke nimesulide slows. Banyere n'aka dosing na oge nke ọgwụgwọ, na ajụjụ ndị a ga-aza ozugbo na ịga dibịa-ewere n'ime akaụntụ na onye e ji mara onye ọrịa na ogo nke ọrịa ntaramahụhụ. Ya mere, anyị na-atụle na n'ozuzu na-atụ aro, nke e dere ozi banyere nkà mmụta ọgwụ "Nimid" ntụziaka ntuziaka.

Mbadamba na-kenyere ndị okenye-adịkarị ugboro abụọ a ụbọchị na 100 mg. Na oké forms nke ọrịa kwa ụbọchị dose nwere ike okpukpu abụọ. -Eto eto nke 12 na afọ 18, na-atụ aro gbakọọ dose nke ọgwụ ọnụego nke 1.5 mg kwa 1 n'arọ ahu aro. Ọ bụrụ na usoro ọgwụgwọ chọrọ nwa bu n'okpuru afọ iri na abụọ, na ya ibu karịa 40 n'arọ, ọ na-kenyere 100 mg nke ọgwụ kwa ụbọchị site nkerisi ọnụego na nkebi abụọ. Na ahụkebe ikpe, ndị dọkịta nwere ike na-atụ aro dose.

Pụtara n'ụdị nsogbu dị iche iche ji na ụmụ isua 12 na ndị okenye: 1 sachet nke ụtụtụ na mgbede. Nke ọdịnaya nke akpa na-diluted na 100 ml nke mmiri ọkụ, na-aṅụ mgbe nri.

Banyere jel "Nimid", ya - bụghị karịa 4 ugboro n'ụbọchị - a mkpa oyi akwa (na-enweghị rubbing) na ozu òkè na ihe ndị kasị oké mgbu. Mgbe iji ọgwụ,-asa aka gị na ncha n'okpuru na-agba ọsọ mmiri.

A ọgwụ na-contraindicated?

Ekwela idepụta ọgwụ ndị na peptic ọnyá afọ ọrịa, oké imebi nke imeju na-na akụrụ, nakwa dị ka hepatotoxic Jeremaya mere ka nimesulide mere eme. Ike contraindicated ọgwụ dị iche iche ọchịchọ na agba ọbara, gbasara obi insufficiency na hypersensitivity otu ma ọ bụ karịa mmiri nke agwọ ọrịa "Nimid Chiefs". Ntuziaka maka ojiji na e dere ozi na ukpan nke eji ego na Nchikota na nwere hepatotoxic ọgwụ maka fever, flu-dị ka na-ekwu na-enyo enyo na nnukwu ịwa ahụ daa ọrịa.

Ma ego n'ụdị a jel, ọ na-adịghị kenyere ọrịa n'okpuru afọ 12 na ndị mmadụ na-ewekarị nfụkasị Jeremaya. Exacerbate ọrịa n'oge ngwa nke agwọ ọrịa nwere ike ịbụ n'ihi dermatitis, anụ unan na-efe efe, dị ka nke ọma dị ka bronchial ụkwara ume ọkụ, nke e mere site ASA. Ọ bụ ya mere adịghị kenyere pụtara "Nimid" na n'elu pathologies. Ntuziaka maka ojiji mbadamba dị otú ahụ ikpe, kwa, a na-agaghị na-atụ aro.

Enwere m ike na-ọgwụ n'oge ime?

Ndị ọkà mmụta sayensị chọpụtara na nisumelid ike-enwe mmetụta na ọmụmụ. Ọzọkwa, ọ na-egbochi njikọ nke prostaglandins, nke na-maara na-na-akpata oligohydramnios, akpa ume ọbara mgbali elu, oliguria na akaghi aka ibelata Batalova duct. Ka iwelie ize ndụ nke idem emem nke oru, nke elu edema na ọbara ọgbụgba mgbe eji ọgwụ "Nimid". Ntuziaka maka ojiji, mbadamba na ụdị ndị ọzọ nke ọgwụ na-nditịm ajuru aju ma n'oge ime na n'oge lactation. Mgbe niile, ndị nọ n'ọrụ ya na mmiri ara nwere ike nweta n'ime ahụ nwatakịrị ahụ na-akpaghasị ịrụ ọrụ nke dị oké mkpa ọ na usoro. N'ọnọdụ ndị ahụ ebe ọ gaghị ekwe omume ime na-enweghị ọgwụ, na abamuru nne kari ihe ize ndụ nke nsogbu na nwa, na onunu ogwu na ọgwụgwọ kpebisiri ike site dọkịta.

mmetụta

Ọzọkwa mma uka pharmacological àgwà, nkwadebe na-nwere otu nnukwu ndepụta mmetụta. Ya mere, ka anyị hụ ihe ụdị omume nwere ike ime mgbe ị na-eji "Nimid". Mbadamba (ntụziaka na Russian na-eme ka data dị) nwere ike ime ka itching, aṅụ, dị iche iche na akpụkpọ ọkụ ọkụ, angioedema, na ụfọdụ nke Stevens-Johnson syndrome na epidermal necrolysis. Gi ike, n'aka nke ya, na-anabata ọgwụ si afọ ntachi, afọ ọsịsa, mgbe ụfọdụ, ndị ọrịa nwere ihe mgbu na afo, ọgbụgbọ. Nnọọ adịkarịghị ọgwụ nwere ike ime ka perforation nke ọnyá afọ na peptic ọnyá afọ na 12 duodenal ọnyá afọ.

Ebe ọ bụ na usoro nke na metabolism na-imeju, ọ na-enwe nsogbu ahụ. Ya mere, ogologo oge nke ọgwụ ụfọdụ, nwere ike ime ka mgbanwe transaminases, cholestasis, jaundice na ọbụna nnukwu ịba ọcha n'anya. Dị ka ụfọdụ n'ime imeju na-abụghị nanị mbadamba na nsogbu dị iche iche na ntụ ntụ, ma "Nimid".

Note kpọmkwem na-akọwa omume mmeghachi omume nke urogenital usoro ọgwụ ochichi. Ọ nwere ike ịdị ka edema, dysuria, urinary njigide, na oliguria, nnukwu gbasara akụrụ odida, interstitial nephritis. The akụkụ okuku ume na usoro nwere ike dyspnea na bronchospasm, ruo ogologo oge iwere nwere ike ime ka mmepe nke ụkwara ume ọkụ.

Tụkwasị na nke a mmetụta, onye ọrịa nwere ike ịzụlite tachycardia, ọbara mgbali elu, hypothermia, ike ọgwụgwụ na ọrịa ndị ọzọ. Fọrọ niile oghom Jeremaya mere na-atụ aro iji kagbuo na nkà mmụta ọgwụ na-achọ nlekọta ahụ ike ozugbo. Iji-abụ na nke a ọnọdụ, ị chọrọ nlezianya na-enyocha niile kwere omume ihe ọmụma banyere ọgwụ na-ewere "Nimid Chiefs" (mbadamba). Ntuziaka maka ojiji, nke bụ na onye ọ bụla ngwugwu ọgwụ nwere ike inyere.

Ovadozu nke ọgwụ ọjọọ na mbụ enyemaka algọridim

Ọ bụrụ na ị na mmadụ na mberede gafere allowable dose, kwesịrị ozugbo gaa ụlọ ọgwụ. Mgbe niile, n'ihi ihe dị otú ahụ njehie nwere ike iro ụra, ọgbụgbọ, vomiting, mgbu espigastrii, lethargy, mụbara ọbara mgbali. Nke a bụ ndepụta nke na ìhè nke Jeremaya mere ka elu dose nke ọgwụ "Nimid". Mbadamba - ntuziaka adọ aka ná ntị banyere nke a - na e ke ego nke 2-3 iberibe karịa kwere ọnụego, nwere ike ime ka esịtidem ọbara ọgbụgba na-eduga akụrụ odida. Na ọgwụ omume, ọbụna ofu obere okwu anaphylactoid Jeremaya mere, akụkụ okuku ume na ịda mbà n'obi na-amaghị onwe ya n'ihi ovadozu nke a ọgwụ.

Ọ bụrụ na anyị na-ime dose na-karịa, na-eche maka adakarị ngosipụta bụghị odot. Ị ga-ozugbo asa si afo, na-osmotic laxative na chelators. Ọkacha mma mgbe n'elu jikoro gaa n'ụlọ ọgwụ, ebe ndị ọkachamara ga-anọgide na symptomatic ọgwụgwọ. Ọ ga-kwuru na ụbọchị ọ dịghị kpọmkwem ngwọta.

Gịnị ka ha na-eche banyere ọgwụ ndị ọrịa?

N'ezie, na ọrịa na nnukwu mgbu fọrọ nke nta niile ọrịa anabata nke ọma na-atụle ọgwụ. Ha mara na mmetụta nke iji ọgwụ ọjọọ eme emee pụtara ngwa ngwa, nke ike ma na-aṅụrị ọṅụ. Ezi ndị ọzọ kwuru nwere ike nụrụ mgbe onye ọrịa e kenyere a ogologo N'ezie ọgwụ ọrịa, "Nimid". Mbadamba (ntuziaka na-atụ aro na uche pụrụ iche na a na pharmacological onwunwe nke ọgwụ) ngwa ngwa kwụsị mgbu, ma mgbe ụbọchị ole na ole nke n'ikuku-eme onwe ha mara mmetụta. The mbụ na-amalite na-eme ka nimesulide eriri afọ tract, ụjọ usoro e mesịrị (nke a na-egosipụta site ogwe, ọnọdụ swings na a ọchịchọ enweghị mmasị).

N'ezie, haa na-ekwu na ọgwụ na-eme ndị ọzọ nsogbu ka mma, ọ gaghị ekwe omume. Mgbe niile, n'ezie, ọ na-enyere aka. Ma, ebe a bụ iji ya na-enweghị na-egosi na ebe ọkachamara adịghị atụ aro.

Ọ bụrụ na n'elu ozi nọgidere na obi abụọ ma ma ọ bụ iji zuru "Nimid" (mbadamba), ntuziaka, reviews, na ntụziaka ndị ọrịa na dọkịta nwere ike inyere ime mkpebi ziri ezi.