"Nitrosorbide" - analogues. Ntụziaka, ojiji, ọgwụ nkọwa

Ala ala obi odida bụ ezigbo nsogbu maka ma ndị agadi ma ndị ọrịa. Nke dị oké mkpa na-akwado ya ọgwụ. Onye ọrịa na ha kwesịrị ịna-eri mkpụrụ ọgwụ na-edu a kwesịrị ndụ. Idepụta Nwere a ruru eru cardiologist. Ewu ewu n'etiti ndị ọkachamara na-"Nitrosorbid" mkpụrụ ọgwụ. Analogs na-eji obere ugboro ugboro.

Hapụ ụdị na mejupụtara

Mbadamba na-otu ìgwè nke antianginal ọgwụ ọjọọ. Isi nọ n'ọrụ mgwa eme dị ka isosorbide dinitrate. Ka excipients eji magnesium stearate, lactose monohydrate, polyvinyl acetate na talc. The mbadamba dị na-acha ọcha, nwere a okirikiri udi.

Isi nọ n'ọrụ mgwa, nke bụ organic nitrate akwalite ntụrụndụ nke vaskụla ezigbo muscle mgbidi. Mmetụta abụghị nanị na akwara ma na veins. Budata belata deposition nke venous ọbara, mbelata venous laghachi obi. Good adakarị ikpughe nwere isosorbide dinitrate. Ntuziaka maka Iji na-ekwu na isi akụrụngwa na-ngwa ngwa etinye obi gị dum n'ime n'ọbara. Site na nke a na-agwọ ọrịa mmetụta na-abịa ngwa ngwa, ngwa bụ ogologo.

Pharmacokinetics

Ke ndidụk afo mbadamba igbari n'ime a nkeji ole na ole. N'ihi na awa ole na ole i nwere ike ugbua hụ mbụ pụta nke ọgwụ. The mbadamba na-etinye obi gị dum ngwa ngwa. Primary ọgwụ bioavailability bụ 22%. The kacha mmetụta ruru mgbe 2 awa mgbe ingestion nke mbadamba. The isi n'ọrụ mgwa na-agbụ na ọbara na-edozi 30%.

Kpamkpam tutu amama ọgwụ si ahụ n'ime 12 awa. Mmetụta dị ukwuu bụghị. Isosorbide dinitrate na-metabolized na imeju. Nke a Nleta ifịk metabolite nke isosorbide mononitrate. The ọgwụ na-fọrọ nke nta kpamkpam anyụpụ na mmamịrị.

na-agba akaebe

"Nitrosorbid" Erere nwere ike ọgwụ nanị site a ruru eru cardiologist. Analogs na-họpụtara ọkachamara na-egosi. The ọgwụ ike ga-eji na ọrịa na ịrịa ọrịa obi, ma ọ bụrụ na ruo ogologo oge ọgwụgwọ na ndị ọzọ ọgwụ enyeghị a mma N'ihi. The mbadamba nwere ike igbochi rịaworo.

The Nchikota ọgwụ nwekwara ike-kenyere ọgwụ "Nitrosorbid". Analogs ike ga-eji dị ka ndị a: "Kardiket" "Of Mick", "Long Dikor". Ọgwụ ndị a ga-atụle a obere ka e mesịrị. The mbadamba nwere ike eji na njikọ na gbasara obi glycosides, diuretinami ma ọ bụ inhibitors.

Olee ihe ọzọ nwere mkpụrụ ọgwụ "Nitrosorbide 'àmà? The na nkà mmụta ọgwụ na-enyere, ma myocardial infarction. The agwọ ọrịa na-ndinọ mgbe myocardial agha ka prophylaxis. Na jikọtara ọgwụ ọgwụ nwekwara ike-eji maka prophylaxis nke rịaworo pectoris. The mbadamba na nke a nwere a ruo ogologo oge ihe.

Ọgwụgwọ na "Nitrorbid" ikekwe n'oge ime na lactation. Otú ọ dị, ọ dị mkpa itinye ọgwụ na ịkpachara anya. The na nkà mmụta ọgwụ na-kenyere naanị ma ọ bụrụ na ndị nwere uru nne kari ike imerụ nwa ọhụrụ.

contraindications

The agwọ ọrịa a tọhapụrụ naanị site ọgwụ. Nke a-ezere na-ekwesịghị ịdị n'ikuku nke mbadamba ọrịa. The eziokwu na ọgwụ "Nitrosorbid" dị ka "Kardiket ghara ', nwere ụfọdụ contraindications. Na ọ bụrụ nwere ike iji ọgwụ ọjọọ na oge nke nnukwu myocardial infarction, ọ bụrụ na e siri hypotension. Na nke a, na mbadamba nwere ike na-abụghị mmetụta. Ọ bụghị prescribers ọma dị ka n'akuku-mmechi glaucoma, hypovolemia, nnukwu ọbara ọdịda. Ọ na-adịghị na-ọgwụ na traumatic ụbụrụ unan.

E nwekwara afọ mgbochi. Mbadamba "Nitrosorbide" ma ọ bụ "Kardiket ghara" nwere ike na-kenyere naanị okenye ọrịa. Ụfọdụ ọrịa nwere ike ime hypersensitivity na nitrati. Ọ bụrụ na e nwere ihe ọ bụla anabata, na-akwụsị na-ewere ọgwụ na ịkpọ a cardiologist.

adọ aka ná ntị

N'ihi enyemaka nke rịaworo ọgụ "Nitrosorbid" mkpụrụ ọgwụ ike ga-eji. The otu nwere ike kwuru banyere ọgwụ 'Of Mick "," Kardiket "na" Long Dikor ". All ndị a ọgwụ ọjọọ nwere ike na-eji maka mgbochi. Ọ bụrụ na onye agha dị nso, ọ ga-achọ ọgwụ na ọgwụ ọjọọ ndị ọzọ. N'oge eji "Nitrosorbid" pellets aghaghị inyocha obi ọnụego, na ọbara mgbali. Ọrịa na-adịghị ala ala obi odida ọgwụgwọ a chọrọ ebe ke ọgwụ ọnọdụ.

Nnọọ kagbuo ọgwụ adịghị atụ aro. N'ikuku "Nitrosorbid" ná mmalite nke usoro ọgwụgwọ pụrụ ịmụba ọnụ ọgụgụ nke anginal ọgụ. Otu mmetụta nwekwara ike ịdị na-eme mgbe a nkọ kagbuo nke ọgwụ. N'ihi cupping ngwa ngwa nitrati ike ga-eji na ọgwụgwọ oge, nke ga-ahọpụta a cardiologist. Self-ọgwụ nwere ike inye na-ejighị n'aka na-arụpụta.

Ekwela nọdụ n'azụ wheel nke ụgbọala, ma ọ bụrụ na ọ dị mkpa itinye a nkwadebe nwere isosorbide dinitrate. Ntuziaka na ngwa na-ekwu na umi bụ ike ime ka iro ụra na dizziness. Jikwaa ọ bụla mgbagwoju usoro n'oge ọgwụgwọ na-adịghị atụ aro.

onunu ogwu

The mbadamba nwere a ruo ogologo oge ihe. Ọrịa na obi odida ndinọ 20 mg otu ugboro n'ụbọchị. Nke nta nke nta dịkwuo onunu ogwu. Oke ọnụego ekwesịghị gafere 3 mbadamba kwa ụbọchị. Na ihe mgbagwoju ikpe, ọ ga-kenyere ogologo-eme n'aka (40 mg). Ọrịa na-ewere na ọkara a mbadamba ugboro abụọ n'ụbọchị. Mụbara onunu ogwu na ịkpachara anya na naanị n'okpuru nlekọta nke ndị ọrụ.

Ọgwụgwọ malitere na a kacha nta onunu ogwu ọnụego na-eji nwayọọ nwayọọ akpọlite ndị kacha irè. E n'ihi na ogologo oge ochichi, mbadamba "Nitrosorbide". Analogues na-na-e n'ihi na ogologo oge ọgwụ. ọgwụgwọ na-adịghị na-atụ aro ka ha kwụsị inikiet inikiet. Ka ịzụlite mmetụta.

ovadozu

Nditịm dị ka dọkịta ahụ nkwanye bụ mkpa na-eji mbadamba "Nitrosorbid". Ibọrọ na-egosi na ihe ovadozu nwere ike ime mmetụta. Ha na-apụta n'ụdị dizziness, ọgbụgbọ, vomiting. Obere nwere ike ime akpụkpọ Jeremaya mere dị ka itching, rashes. Cardio-vaskụla usoro ọrịa nwere ike na-eche a ịrịba Mbelata ke ọbara mgbali, obi palpitations.

Ọgwụgwọ nke ovadozu nwere ike rụrụ naanị na a ọgwụ. First rụrụ gastric lavage. Mechara symptomatic ọgwụ. Iji ngwa ngwa akawanye ọrịa na-arịa ga-eji rụọ ọrụ carbon.

mmetụta

Mgbe e ji n'ụzọ kwesịrị ekwesị, bụ mbadamba nkume nwekwara ike ịzụlite mmetụta. N'ọnọdụ ka ukwuu, ha na-adịru nanị nwa oge na-anaghị achọ discontinuation ọgwụgwọ. Wetara ihe mgbaàmà na mmalite nke usoro ọgwụgwọ nwekwara ike ime ka mbadamba "Dikor Lorng" "Of Mick", "Kardiket". Ná mmalite, ọrịa nwere ike na-egosi isi ọwụwa, nke ike-adị site na ọgwụ ọ bụla ma na-aga n'ebe a ụbọchị ole na ole mgbe nnabata nke ọgwụ. nwekwara ike-hụrụ tachycardia, ebelata ọbara mgbali.

Si digestive usoro mmetụta na-egosipụta ụdị ọgbụgbọ, abdominal mgbu, afọ ọsịsa. Mgbe vomiting kwesịrị ịchọ ozugbo ọgwụ ndụmọdụ.

ọgwụ interactions

Ịkpachara anya ga-eji "Nitrosorbid" mbadamba ọ bụla vasodilators. Ndị dị otú ahụ na mmekọrịta pụrụ iduga mmetụta. Na dihydroergotamine mbadamba ike ga-eji nanị mgbe hụ dọkịta. Drug interactions nwere ike ịkpata ihe abawanye na ọbara ịta nke dihydroergotamine ma welie ya hypotensive mmetụta.

Akwalite mgbasa jikọtara ojiji na mbadamba "Nitrosorbid" acetylsalicylic acid. Otú ọ dị ọgwụ adịghị atụ aro maka ojiji na adsorbents. Dị otú ahụ na mmekọrịta ga-eduga a ọnụ na bioavailability nke ọgwụ.

analogs

Ewu ewu n'etiti ndị ọkachamara na-"Nitrosorbid" mkpụrụ ọgwụ. Low price nke ọgwụ, na ọ e ji enwe mmetụta dị ahu. Ma iji chọta a na nkà mmụta ọgwụ na a na-ere ọgwụ ọ bụghị mgbe niile kwere omume. The cardiologist ga-enyere ịhọrọ elu-edu ogbo. "Kardiket" mbadamba na-na-n'ụzọ zuru okè ịnagide ọrụ. Isi nọ n'ọrụ akụrụngwa nke ọgwụ bụ ka otu isosorbide dinitrate. The na nkà mmụta ọgwụ na-kenyere maka nzube nke prophylaxis nke rịaworo pectoris na myocardial infarction.

More oké ọnụ ogbo bụ mbadamba "Dikor Long." Inyeaka Efrata eji na mbadamba ọka starch, lactose monohydrate, colloidal sịlịkọn dioxide, magnesium stearate, titanium dioxide. The mbadamba nwere ike ọgwụ na ụmụ na ụmụ nwaanyị dị ime na ndị ụlọ ọgwụ.

Mbadamba "Of Mick" - ọzọ na-ewu ewu na ngwá ọrụ na ike dochie nkà mmụta ọgwụ "Nitrosordid". Isi nọ n'ọrụ mgwa bụkwa isosorbide dinitrate. Nke ndị a niile ọgwụ, nke a bụ ihe kasị oké ọnụ.

Nyocha nke mbadamba "Nitrosorbid"

The ọgwụ nwere mmetụta dị mma na obi usoro. Na obi ọdịda, agafeghị oke na akpa ebe họpụtara mkpụrụ ọgwụ "Nitrosorbid". Price ọgwụ obi ụtọ ọrịa. Otu mkpọ nwere ike zụrụ maka naanị 15 rubles. The na-ezighị ezi reviews nwere ike ejikọta ya na mmetụta na-erukwa na mmalite nke ọgwụ. Ọ bụ uru na-echeta na ha bụ ruo nwa oge.

The na nkà mmụta ọgwụ na-ekwesịghị-eji naanị ya. The ọgwụgwọ ga-ebe nditịm n'okpuru nlekọta nke a ọkachamara, onye ga-ekpebi na ezi usoro onunu ogwu na nke ọ bụla. Nnọọ kagbuo ọgwụ nwekwara ekwesịghị ịbụ.