Phosphatidic acid. Njikọ na ihe dị n'ime ahụ

Site na echiche nke usoro ahụ, phosphatidic acid bụ phospholipid dị mfe.

Nke a bụ otu n'ime akụkụ nke abụọ nke metabolism nke phosphoglycerides na ahụ dị ndụ.

A na-enye nlezianya nke ihe ndị a n'ihe ọmụmụ nke ọrụ mgbaàmà nke ogige chemical.

Ruo ugbu a, ọ bụghị njikọ niile nke metabolism nke acid acid phosphatidic doro anya, karịsịa, ajụjụ nke usoro nke nnyefe nnyefe site na ogige ndị a, nakwa dị ka ọnụnọ nke ala ionophore na acid phosphatidic, ka a na-atụle.

Njikọ nke phosphatidic acid

Ejiri phosphatidic acid guzobe n'okpuru nduzi nke phospholipase D. Nke a na nke enzymes nwere oke ọrụ na njikọ nke acid phosphatidic. N'ịbụ onye na-emepụta ọgwụ dị mkpụmkpụ, e mesịa, a na-emepụta ihe a n'okpuru nduzi nke phosphohydrolase na diglyceride (n'ihi mbido dephosphorylation).

Mgbe ị na-emekọrịta otu enzyme ahụ, phosphatidic acid nwere ike gbanwee dị ka diacylglycerol, nke na-arụ ọrụ nke activator nke prozy protein kinase C na ngwangwa nke mmeghachi omume nke ndụ.

Mmetụta nke phosphatidic acid pụtara na anụ ahụ dị mma. Usoro na-amalite site na adipocytes (mkpụrụ anụ abụba) nke abụba abụba guzobere site na hydrolysis nke abụba (nke kachasị dị elu lipoproteins). N'ime mkpụrụ ndụ ndị ahụ, na-eji glycerol-tri-phosphate na-emekọrịta ihe, a na-eme ka acy fatty dị na lysophosphatidic acid, bụ nke sitere na nke ahụ mepụtara phosphatidic acid.

Ụdị nke e si na ya nweta glycerophospholipids nwere sụpụta phosphoric na fatty acids, glycerin, yana nitrogen-nwere acid residues.

Uru nke phosphatidic acid

Emeela ka o doo anya na phosphatidic acid bụ nke a na-akpọ ogige ndị na-egosi akara, ya bụ, na ha na-ebu ọrụ nke ndị na-etinye aka na ntinyefe ozi na ụzọ mgbaàmà. Karịsịa, ọ bụ njikọ dị mkpa na ntinye nke mgbaàmà ndị na-esonụ n'ime mkpụrụ osisi:

• Ntinye;
• Osmotic, nke dị mkpa na mmepe nke azịza nke cellular na-aza ụdị nsogbu a.

N'oge a nwalere ya, a gosiri na ọkwa nke onyinye a na mkpụrụ ndụ nke ihe ọkụkụ dị iche iche n'okpuru mmetụta nke ihe ndị na-akpata ọrịa na-arịwanye elu. Omume dị otú a sitere na:

• Nsogbu Osmotic.
• Ngosipụta na ala okpomọkụ.
• Mmetụta nke ihe ụfọdụ na-arụ ọrụ na-arụ ọrụ na-arụ ọrụ na-emepụta ihe (phytohormones).

Ya mere, o nwere ike kwubie na phosphatidic acid na ndị metabolites na-ekere òkè na mgbagwoju nke mmeghachi omume nke na-eme ka a gbanwee akụkụ ahụ na ọnọdụ ndị siri ike.

Tụkwasị na nke ahụ, a maara na phosphatidic acid dị mkpa maka ịkwagharị protons na ions calcium site na ụbụrụ nke neurons na ụbụrụ muscle. Site na nke a, phosphoric acid na-ekwu na ọrụ ionophore (họrọ: maka calcium na ions proton).

Nhazi nke nsụgharị

N'agbanyeghi na ebumnuche nke phosphatidic acid guzobere, a ghaghi ikwuputa uzo ozo nke ntinye ihe ngosi a ma kwesiri ka edozi ya.

Otú ọ dị, obi abụọ adịghị ya na mmụgharị sitere na ike nke phosphatidic acid, na-emetụta usoro nke cell membrane, na-achịkwa ọrụ nke enzymes membrane, nakwa na-ekere òkè na mkparịta ụka na cellular membranes nke protein molecules.

Ojiji nke phosphatidic acid

Nnyocha banyere ọrụ antioxidant nke ọgwụ phosphatidic acid, nke eduziri ma na ọmụmụ nke usoro ihe nlereanya na ihe metụtara ihe ndị dị ndụ, egosiwo na mimetics nke phosphatidic acid nwere usoro dịgasị iche iche nke arụ ọrụ antioxidant.

Ihe omuma di omimi banyere izizi nke ihe phosphatidic acid mere ka o kwe omume iji ya na ndi metabolite n'ime mmeputa ihe omumu ihe ndi ozo iji kwalite ikike oru na ntachi obi nke aru aru.

Na-arụ ọrụ n'obere cellular, ogige dị otú ahụ adịghị akpali, mana ọ bụ naanị normalize ọrụ sel; Isi ihe dị mkpa na-ebelata ihe ga-esi na ya pụta.