"Simvastatin": reviews, na-egosi maka ojiji, price na analogues

Gịnị mere m mkpa ọgwụ "Simvastatin"? Nleba banyere ọgwụ ga-ọkọnọ a obere n'ihu. Anyị na-agwa gị banyere nke a ọgwụ dị na a ụdị nke ọ nwere na-egosi, mmetụta na contraindications ogbo, ole ọ na-efu, otú ọ ga-ekwesị etinyere na na. D.

Packaging, Product ụdị na mejupụtara

Drug "Simvastatin" na-aga na-ere n'ụdị mbadamba. Ha nwere gburugburu biconvex udi na akara na otu aka, nakwa dị ka na-acha ọcha. Ntekwasa mbadamba, dị mbadamba nwere 10 mg nke simvastatin. Ọzọkwa agwọ ọrịa na-agụnye inyeaka mmiri ka butylhydroxyanisole, lactose, magnesium stearate, starch prozhelatinizirovannogo, talc, na microcrystalline cellulose.

Na a ngwugwu, ị nwere ike ịzụta ọgwụ "Simvastatin"? Egosi maka ojiji nke ego kpọmkwem na ntụziaka, nke a na-dị na a mkpọ katọn. E nwekwara-enịm na abụọ blisters na mbadamba (10 mbak).

pharmacological mmetụta

Olee otú ọgwụ "Simvastatin"? Ọbịa ọkachamara na-egosi na nke a lipid-ẹsụhọde ọgwụ ọjọọ. Ọ na-emepụta synthetically.

Atụle gị n'ụlọnga bụ ihe na-adịghị ejekwa lactone. Na ụmụ mmadụ, ọ bụ hydrolyzed, na ekemende Nleta a hydroxy-acid emepụta.

Jiri nke ọgwụ adịghị ime ka ìgwè nsị. Ọ na-ngwa ngwa metabolized na-agụnye ọtụtụ usoro nke synthesizing.

Njirimara nke ọgwụ

Gịnị Njirimara nke ọgwụ "Simvastatin"? Nyocha haa na ngwá ọrụ a na-enyere aka belata plasma etoju nke triglycerides, ngụkọta cholesterol na ala-na-njupụta lipoprotein.

The ọgwụgwọ mmetụta mgbe ị na-amalite na-ewere ọgwụ na-adị n'ime izu abụọ. The edinam nke ọgwụ na-anọgide ufọk ufene maka oge nke ọgwụgwọ. Mgbe kagbuo mbadamba cholesterol larịị nwayọọ nwayọọ na-alaghachikwuru mbụ arụmọrụ.

Pharmacokinetics

ọgwụ ọjọọ, "Simvastatin" Olee otú ogologo na-etinye obi gị dum? Ọbịa ọkachamara na-ekwu na absorption nke ego dị nnọọ elu. Mgbe e ọgwụ n'ime ya kasị elu ịta na ọbara ruru mgbe 1.5-3 awa na-belata 90% mgbe banyere 12 awa. Communication na plasma bụ mkpokọta 95%.

The metabolism nke ọgwụ na imeju. Ọkara ndụ-nke ahụ metabolites bụ awa abụọ.

Egosipụta agwọ ọrịa na na nsị nakwa site na akụrụ ya.

Drug "Simvastatin": egosi maka ojiji

Nke ego na-atụ aro maka ojiji na hypercholesterolemia, na ịrịa ọrịa obi. Nye iwu ndị dị otú ahụ na nkà mmụta ọgwụ ga na-enwe a dọkịta mgbe a ọgwụ nnyocha.

Ya mere, na ihe ọ bụla ikpe, i nwere ike na-mbadamba "Simvastatin"? Site na ihe ọ pụtara na e kenyere? Dị ka ntụziaka, ọgwụ na-atụ aro mgbe:

• isi hypercholesterolemia;
• adịghị ike nke ndị na-eri na ala cholesterol nri na ndị ọzọ na-abụghị ndị ọgwụ ọjọọ adọ (arọ ọnwụ, ọrụ ahụ) na ọrịa na akwara atherosclerosis;
• jikọtara hypertriglyceridemia na hypercholesterolemia, nke na-adịghị gbazie ahụ ibu na pụrụ iche nri.

Na ihe ndị ọzọ ọgwụ ọgwụ "Simvastatin"? Egosi maka ojiji nke ngwá ọrụ a tụlee ugbu a:

• mgbochi nke myocardial infarction;
• mbenata ihe ize ndụ nke ọrịa nke obi (eg, na-akwụsị akwụsị ischemic agha ma ọ bụ ọrịa strok);
• iberibe nke atherosclerosis ke akwara arịa.

contraindications

Ugbu a na ị maara ihe ọgwụ na-kenyere "Simvastatin". Egosi maka ojiji nke ngwá ọrụ e ọkọnọ n'elu. Otú ọ dị, nke a ọgwụ e nwere contraindications. Ndị na-esonụ ọnọdụ na-emetụta ha:

• muscle ọrịa (ma ọ bụ na-akpọ myopathy);
• ọrịa imeju na-ewere ọnọdụ na-arụsi ọrụ ike na-adọ;
• afọ 18 afọ;
• persistent elu nke imeju enzymes (gụnyere amaghị etiology);
• hypersensitivity ọgwụ ma ọ bụ na ya na onye mmiri (gụnyere lactose ekweghị ibe nọrọ);
• hypersensitivity ọzọ n'aka statin usoro.

Nlezianya kwadebe n'ikuku

Agwọ ọrịa "Simvastatin", ego nke nke na-egosi n'okpuru, ha na-elekọta nyere ndị ọrịa na-aṅụ oké mmanya, nakwa dị ka ndị mmadụ na-esonụ ngwa transplantation (na immunosuppressive ọgwụ).

Ọzọkwa, isiokwu pụtara na-elekọta e ke ọnọdụ na-eduga mmepe nke gbasara akụrụ odida (e.g., hypotension, nnukwu ọrịa nke na-efe efe uwa, belata, ma ọ bụ, na Kama nke ahụ, ihe mụbara tonus nke muscle anụ ahụ, kwuru metabolic na endocrine ọrịa, àkwụkwụ, electrolyte itule n'ọgba aghara, ịwa ahụ, gụnyere eze na trauma).

Drug "Simvastatin": n'iji na onunu ogwu

Weere tupu wetere ọgwụ pụtara onye ọrịa ga-ata a ọkọlọtọ hypolipidemic nri. Na mberede, ọ ga-agbasoriri ofụri ọgwụgwọ.

"Simvastatin" mbadamba ndinọ ozugbo kwa ụbọchị na mgbede. Mgbe na-ewere nke a ọgwụ ga-gaghị adaba oriri nke nri.

The na-atụ aro usoro onunu ogwu maka ọgwụ ọgwụgwọ nke hypercholesterolemia bụ 10-80 mg kwa ụbọchị.

dose mgbanwe a ga-rụrụ na kwa ọnwa etiti oge. First, onye ọrịa ga-10 mg, mgbe ahụ, 20, 30 na na. D. Ọtụtụ ikpe ezigbo ọgwụgwọ mmetụta na-enwetara mgbe anata 20 mg nke ọgwụ.

The onunu ogwu nke ọgwụ na-adabere na ọrịa afọ, ya ọnọdụ na na. Na nke a, ndị dị otú ahụ a usọbọ ga-ahọpụta a dọkịta, mgbe ọ tụlesịrị onye ọrịa ahụ na ọgwụ nnyocha.

oghom Jeremaya mere

Dịka ọ dị na ọgwụ, agwọ ọrịa "simvastatin" na-nwere mmetụta. Otu n'ime ihe ndị kasị nkịtị na-esonụ:

• Abdominal mgbu, ịba ọcha n'anya, afọ ntachi, pancreatitis, flatulence, vomiting, elu imeju enzymes, afọ ọsịsa, na ọgbụgbọ.
• Asthenic syndrome, mkpọchị uche nke uto, isi ọwụwa, bịara ikiri ọhụụ, dizziness, elu neuropathy, ehighi ura, paresthesia, muscle cramps.
• Angioedema, eosinophilia, polymyalgia rheumatica, urticaria, lupus-dị ka syndrome, vasculitis, dyspnea, thrombocytopenia, na-ekpo ọkụ mgbukepụ, mụbara erythrocyte sedimentation ọnụego, flushing nke anụ, fever, photosensitivity, ogbu na nkwonkwo.
• Skin ọkụ ọkụ, alopecia, dermatomyositis, itching.
• Myopathy, rhabdomyolysis, myalgia, adịghị ike, muscle cramps.
• Anaemia, belata potency, obi, gbasara akụrụ odida (nnukwu).

Special ntuziaka maka inweta agwọ ọrịa

N'ihu iji ngwaahịa ị ga na-agụ ntụziaka ọma. Ọ na-ekwu na:

• tupu mmalite nke ọgwụ dị mkpa iji na-eduzi a ọmụmụ nke imeju;
• ọgwụ ọjọọ, "Simvastatin" kwesịghị iwere bụrụ na nke gbasara akụrụ odida na ihe ize ndụ nke rhabdomyolysis;
• ọgwụ nwere ike oghom mmetụta na nke nwa ebu n'afọ;
• ọ na-adịghị na-atụ aro na-ọgwụ ndị inyom nke ịmụ nwa afọ na-adịghị iji gbochie afọ;
• n'oge ọgwụgwọ na-ekwesịghị ṅụbigara mmanya ókè;
• n'oge ọgwụ, onye ọrịa ga-esoriri na hypolipidemic nri;
• imekotaotuugbo n'ikuku nke mmiri grape ike welie ogo ogo n'akụkụ Jeremaya mere;
• nkwadebe pụrụ ịdị irè dị ka a monotherapy, na ya na ojiji nke bile acid sequestrants.

Analogs na-eri nke ọgwụ

Ugbu a, ị mara na bụ ọgwụ "Simvastatin". Analogues, ego nke a na nkà mmụta ọgwụ a ga-enye ugbu a.

Ọ bụrụ na ọ gaghị ekwe omume na ngwa nke a pụtara nwere ike dochie anya na ndị ọzọ ọgwụ ọjọọ eme ihe ndị dị otú ahụ dị ka "Simvakard", "Avestatin", "Holvasim", "Aktalipid", "Sinkard", "Aterostat", "Simplakor", "Vasilip", "Simli" "Vero -Simvastatin "," Simgal "," Zovatin "," Simvor "," Zocor "," Simvastol "," Zorstat "," Simvalimit "," Ovenkor "," Simvakol "," Simvageksal "na t. d.

Price ọgwụ ọjọọ "Simvastatin" bụghị nnọọ elu na bụ banyere 240 rubles 20 mbadamba.

Nyocha nke agwọ ọrịa

Ọtụtụ ndị ọrịa mgbe a na "Simvastatin" mbadamba, mara ya elu arụmọrụ. The ọgwụ bụ ngwa ngwa lowers cholesterol, na-egbochi mmepe nke ọrịa dị iche iche.

Otú ọ dị, ụfọdụ ndị ọrịa bụ ndị obi ụtọ na-agafe mgbe omume cholesterol larịị adahade ọzọ na mgbe na-abịa ntọala.