"Singulair": onye na-akụziri nkọwa

Hapụ ụdị ọgwụ na ndị Efrata: gburugburu, oval, square chewable mbadamba. Ime umi - montelukast, nke na otu Lonely mbadamba "Singulair" - 4 mg; ntụziaka ọdịnaya na-egosi a enyemaka nke Efrata: mannitol, microcrystalline cellulose, giproloza, ígwè oxide red, croscarmellose sodium, udara flavor, aspartame, magnesium stearate. Ngwugwu nwere abụọ blisters, onye ọ bụla nke 7 mbadamba. Ke adianade do, "Singulair" na-agbala n'ụdị mbadamba 5 mg na 10 mg, na a siri ike shei, nke na-e n'ime.

Egosi maka Iji "Singulair": Ntuziaka nye iwu nye iwu usọbọ maka bronchial ụkwara ume ọkụ (mgbochi na ọgwụgwọ) na ndị okenye na ụmụaka si afọ 2 afọ. Kwukwara na mkpụrụ ọgwụ iji belata mgbaàmà nke imi nsụchi na ụmụaka okenye karịa 2 afọ, ọ bụla na-akpata (n'oge a kara aka na perennial); maka mgbochi nke ọrịa mgbaàmà n'ehihie na n'abalị; maka ọgwụgwọ nke ụkwara ume ọkụ na ndị na-enwe mmetụta ọsọ ọsọ na aspirin; maka mgbochi nke bronchospasm mere site mmega.

Pharmacological edinam 'Singulair' mbadamba: Ntụziaka na-egosi na montelukast bụ a leukotriene ihe nnabata-eti ọkpọ. Ọ na-egbochi ahụ cysteinyl leukotriene ihe nnabata epithelium nke ọgwụgwụ na karị, mgbe nwekwara gbochie bronchoconstriction mere site penetration nke cysteinyl-leukotriene na akụkụ okuku ume na usoro nke ọrịa na-ata ahụhụ site na bronchial ụkwara ume ọkụ.

Contraindications ojiji nke 'Singulair': Manual machibidoro ojiji nke ọgwụ na ikpe nke na hypersensitivity ya Efrata.

Mmekọrịta: "Singulyar®" nwere ike iwere ya na ndị ọzọ n'aka conventionally eji maka ọrịa nke bronchial ụkwara ume ọkụ. Montelukast enweghị a clinically ịrịba utịp ke edinam ọgwụ: theophylline, prednisone, prednisone, ụfọdụ onu gbochie afọ, terfenadine, digoxin na warfarin. AUC nke montelukast na ọrịa concurrently emeso ya na phenobarbital, ebelata banyere 40%.

Ọgwụgwọ 'SINGULAIR' na-eduga onye ọzọ ọgwụgwọ mmetụta ndị na-ewere kuru corticosteroids. Dose corticosteroids ga-belatara nwayọọ nwayọọ n'okpuru nlekọta nke ndị ọrụ. N'ihi na ụfọdụ ndị ọrịa mma mgbe omume na kuru glucocorticosteroids nwere ike ịkagbu.

Na na vitro nwere kpughere na montelukast bụ ike nke na inhibiting na isozyme CYP2C8. Otú ọ dị, na-amụ ọgwụ interactions na vivo montelukast na rosiglitazone bụghị natara nkwenye nke mgbochi nke a isoenzyme montelukast. N'ihi ya, na-eme, ọ na-adịghị iche na montelukast ga-emetụta ndị metabolism onye ogbugbo ya CYP2C8 isoenzyme na a ọnụ ọgụgụ nke ọgwụ, gụnyere rosiglitazone, paclitaxel, repaglinide.

Ngwa nke ime na oge nke "Singulair" lactation nkwadebe: Guide na-atụ aro iji ọgwụ ọjọọ na mgbe ahụ bu n'obi mmetụta dị mma na nne-enwe n'elu nwere ihe ize ndụ ahụ ike nke nwa ebu n'afọ ma ọ bụ nwa ọhụrụ.

Mmetụta pụrụ iyi n'ụdị nfụkasị Jeremaya: anaphylaxis, angioedema, ọkụ ọkụ, pruritus, urticaria; na obere okwu, na ụdị - of eosinophilic infiltrates na imeju. Na CNS mmetụta n'ụdị na-egbuke egbuke ọhụrụ nrọ, ịmụ anya arọ nrọ, lethargy, ogwe, excitation, gụnyere ime ihe ike, ike ọgwụgwụ, ehighi ura, paresthesia / hypoesthesia, isi ọwụwa; ukwuu adịkarịghị n'ụdị - ọdịdọ. Na digestive usoro ngosipụta: ọgbụgbọ, vomiting, dyspepsia, afọ ọsịsa, abdominal mgbu. Na nweekwa usoro - Mgbaàmà: arthralgia, myalgia, gụnyere muscle cramps. Ọzọ oghom ihe ndị mere na ọnọdụ: intensification nke agba ọbara, guzobere subcutaneous infiltration.

Dosing 'Singulair' nkwadebe: Ntuziaka maka ojiji na-chọrọ na-na, bụ mma tupu ị lakpuo ụra, n'ihi na ndị okenye na ụmụaka ndị nwere ihe karịrị afọ 15 - 10 mg / ụbọchị; ụmụ 6-14 afọ - 5 mg / ụbọchị.

Nchekwa: Store na dịghị mmiri ntụpọ na-enwe okpomọkụ agaghị ukwuu karịa 25 ° C. Mbadamba bụ usable maka 2 afọ.