"Siofor 500"

"Siofor 500" - a ọgwụ na-eji belata ọbara glucose na ọrịa na-arịa ọrịa shuga mellitus. Dị ọgwụ naanị na mbadamba ụdị, ọ na-kpuchie site a pụrụ iche envelopu na-zubere maka esịtidem n'ikuku.

N'ọrụ umi nke na-eji na njikere nke "Siofor 500 'bụ metformin hydrochloride. The inyeaka mmiri na-agụnye magnesium stearate, povidone, hypromellose, titanium dioxide, macrogol 6000.

The pharmacological edinam nke ọgwụ bụ n'ihi nke na biguanide otu. Na kpọmkwem kọntaktị ọbara eruba na gosipụtara hypoglycemic mmetụta (ọnụ nke glucose ịta). "Siofor 500 'adịghị eme ihe na pancreatic secretory ọrụ, n'ihi ya, mgbe ihe nke insulin larịị adịghị agbanwe. Active umi metformin egbochi gluconeogenesis na glycogenolysis, si otú, na mmepụta nke glucose na imeju mkpụrụ ndụ na-ebelata. Ọ na-enwekwu ndị na-muscle uche ka insulin, egbochi absorption nke umi ke eriri afọ. Yiri mmetụta mgbe ụfọdụ na-ekwe ka iji "Siofor 500" n'ihi na arọ ọnwụ. The ọgwụ nwere ọtụtụ ihe ndị ọzọ bara uru Njirimara, nke na-agụnye mkpali nke intracellular glycogen njikọ, mụbara glucose iga ike nke akpụkpọ ahụ na-edozi, lowers cholesterol, triglycerides.

The kacha ọgwụ ịta a hụrụ mgbe na-ewere dị ka awa abụọ. Nri oriri na-ebelata a ọnụ ọgụgụ. Ihe na-egosi bioavailability bụ iri ise percent. The ọgwụ na-anyụpụ na mmamịrị. The ọkara ndu nke mmiri ana isii na ọkara awa. Site na mbenata ọtọ ọrụ nke akụrụ ifịk akụrụngwa na-abawanye. Ọzọkwa, na ọbara plasma ụba ọdịnaya nke nọ n'ọrụ umi Nwa.

Dose kpebisiri ike n'otu n'otu. Ọ na-ekpebisi ike site na ịta index ọbara glucose etoju. Ọgwụgwọ a rụrụ na ụkpụrụ nke a nwayọọ nwayọọ na-abawanye na dose. The ọgwụ ga-a n'oge na ojiji nke nri, na-aṅụ nnukwu quantities nke mmiri mmiri, ọ bụghị na-ata. Two-oge n'ikuku-ekwe omume nanị na a dose nke bụ ihe karịrị otu Erere kwa ụbọchị. Duration ọgwụgwọ kpebisiri ike site dọkịta. Agbaghara nkwadebe usoro ike chefuo maka ojiji nke ịrịba quantities nke mbadamba. Dose kwesịrị ozugbo belata na ọdịdị metabolic ọrịa.

"Siofor 500" bụ ọgwụ na a ga-eji n'okpuru nlekọta nke ndị ọrụ. Ma ọ bụghị ya, nsogbu ịzụlite, isi nke nke na-agụnye lactic acidosis, akụkụ okuku ume na ọrịa, adịghị ike, ọgbụgbọ, vomiting, iro ụra, afọ ọsịsa, hypothermia, abdominal mgbu, mpiaji ọnụ ke obi ọnụego, mgbagwoju anya, na ọnwụ nke nsụhọ. Ọzọkwa, e ji ọdịdị megaloblastic anaemia, nfụkasị Jeremaya.

N'oge oge nke dọkịta dị mkpa iji dokwuo anya contraindications na ojiji nke ọgwụ. Ndị bụ isi na-arịa ọrịa shuga na ketoacidosis, Coma, mkpọchị gbasara akụrụ, hepatic ọrụ, myocardial infarction, obi ọdịda, na-efe efe ọrịa, trauma, ịwa, hypersensitivity ka onye mmiri. Ị nwere ike iji ọgwụ maka ụbọchị ole na ole tupu radionuclide ọmụmụ.

Otu ihe dị mkpa contraindication iji ọgwụ bụ n'oge ime, lactation. "Siofor" na-aba n'anya na-emegide, a Nchikota nwere ike a na-akpata oké metabolic nsogbu, nke na-achọ iji kpochapụ mkpochapu precipitating ihe na ngwa nke symptomatic ọgwụ.