Drug "Doxycycline", analogues na ha na-akpata.

"Doxycycline" na-ezo na antimicrobial maka systemic were. Nakwa dị ka onwe m "Doxycycline" analogues nke ọgwụ esịne ke tetracyclines otu. Ha nwere a nso zuru ezu obosara edinam iji na Iguzogide germs.

The kasị ama na nkwadebe "Doxycycline" ogbo - a "JUnidoks soljutab", "Doxycycline gidlohlorid", "Doksibene", "Doxycycline-Darnitsa" na ụfọdụ ndị ọzọ. Ọtụtụ mgbe, ị pụrụ ịhụ otú ndị mmadụ nwewe obi abụọ ihe ọ ga-azụ, "Doxycycline" ma ọ bụ "JUnidoks", n'ihi na ihe atụ. Ọ ga-kwuru na pharmacodynamics na ndị a formulations bụ otu ihe. Ya mere, ha na-arụsi ọrụ megide gram-mma (Stamphylococcus spp., Streptococcus spp. , Actinomyces Israeli, Clostridium spp., Listeria monocytogens, nje na-akpata anthracis) na gram (nke Neisseria gonorrhoeae, nke Vibrio cholerae, nke Bordetella pertussis, nke Yersinia spp., Of Enterobacter spp., Klebsiella spp., Escherichia coli, Salmonella spp., Shigella spp.) mikroargonizmov. Chebaara "doxycycline" na ya analogues Mycoplasma spp., Rickettsia spp., Treponema spp., Borrelia burgdorferi, Chlamydia spp., Ụfọdụ nke mfe (gụnyere Entamoeba histolytica, Plasmodium falciparum). Kasị chebaara analogs "Doxycycline» Haemophilus influenza (91-96%) na intracellular pathogens.

The naanị mkpa zuru ezu nke dị iche na nke ọgwụ, "Doxycycline" ogbo - ya bụ na ọ dị obere karịa ọzọ n'aka nke tetracycline ime nsia osisi, nakwa dị ka oge nke edinam ọzọ bụ na ihe zuru ezu absorption. Ọgwụ nje si tetracycline usoro banye n'ime mkpụrụ ndụ na inhibit uto nke pathogens, dị n'ebe. Dị ka ogo ọrụ nke nje nkwadebe "Doxycycline hydrochloride" bụ nke ka ndị ọzọ nile na tetracyclines, gụnyere eke.

Dị ka ọgwụ "Doxycycline", ya analogues nwere ndị na-esonụ na-egosi:

- infektsyai otolaryngology;

- akụkụ okuku ume na tract ọrịa;

- na-efe efe nke genitourinary usoro;

- adụ anụ ahụ ọrịa, na akpụkpọ;

- ọrịa nke biliary tract na eriri afọ tract;

- osteomyelitis, brucellosis, whooping ụkwara;

-sifilis, yersiniosis, ịba, yaws, Q fever, legionellosis, ọrịa ịba, ịba ahụ ọkụ, ọrịa Lyme, chlamydia dị iche iche orunótu, bacillary na amoebic ọnyụnyụ ọbara, ọrịa ọgbụgbọ na ọnyụnyụ, tularemia, actinomycosis;

- dị ka akụkụ nke a ngụkọta ọgwụgwọ - granulocytic ehrlichiosis, leptospirosis, psittacosis, Ọrịa anya bụ trachoma, psittacosis;

- subacute nje endocarditis, septicemia, peritonitis.

Ọ machibidoro iji "Doxycycline" na a siri ike uche na tetracyclines, oké imeju ọdịda, porphyria, afọ ime, lactation (maka oge nke ọgwụ si ara kwesịrị ajụ), ụmụ noo ruo 12 afọ. Anya ga-ọgwụ maka ndị nwere ọrịa ntutu ịdapụsị imeju ọrụ, leukopenia.

Drug "Doxycycline" nwere ike oghom mmetụta na:

- ụjọ usoro (ihe nke na-egbu egbu ọdịdị nke Central ụjọ usoro, intracranial mgbali n'elu nkịtị);

- akụkụ nke ntị (mkpọtụ na-egosi na nti);

- digestive usoro (enterocolitis, vomiting, ọgbụgbọ, afọ ọsịsa ma ọ bụ afọ ntachi, mgbu, dysphagia, glossitis, esophagitis, ngosipụta nke afo na duodenum 12);

- na obi usoro (edema, tachycardia);

- akụkụ nke hematopoiesis (thrombocytopenia, eosinophilia, haemolytic anaemia, neutropenia, porphyria);

- mmeghachi omume, na-egosi ihe anataghi (akpụkpọ nācha ọbara-ọbara, itching, anaphylactoid mmeghachi omume, maculopapular ọkụ ọkụ, Stevens-Johnson syndrome, antigionevrotichesky edema);

- ọzọ (ịba ọcha n'anya, jaundice, myalgia, arthralgia, photosensitivity, oké achagharị nke nha nha Enamel, mbufụt na anogenital ebe, candidiasis, goiter).

Na ihe ovadozu nke "Doxycycline" i nwere ike na-achọpụta ndị na-esonụ mgbaàmà: hepatotoxicity, ọzọ akpọ mmetụta. Na nke a, ị kwesịrị ị na ozugbo amalite ike na-elekọta, iwepu ọgwụ na-eduzi symptomatic omume (ebe ọ bụ na ọ dịghị ihe ngwọta), ị ga-enwe na ileba anya, otú ọ na-esi dị mkpa ọrụ.