"Fenilin": ntuziaka maka ojiji, analogs, reviews

Ihe ndị mmadụ na-ekwu banyere ndị dị otú ahụ a nkwadebe dị ka "Fenilin"? Nyocha nke dọkịta na ndị ọrịa ga-atụle na njedebe nke isiokwu. Anyị na-agwa gị banyere nzube nke na ọ na-kenyere usọbọ, otú kwesịrị ekwesị na-anabata, ma ọ bụrụ na o nwere ọ bụla mmetụta, na contraindications ogbo.

The mejupụtara na udi

Na ihe n'ụdị na-mere na nkà mmụta ọgwụ "Fenilin"? Ntuziaka maka ojiji na-akọ na a ọgwụ dị na mbadamba, na-arụsi ọrụ ike umi nke bụ phenindione. Inyeaka mmiri eji lactose, starch, citric acid na talc.

pharmacodynamics

Olee ihe nwere pharmacological ọgwụ "Fenilin"? Ntuziaka maka Iji na-ekwu na ọgwụ na-emetụta na ọbara clotting. Ọ bụ ihe na anticoagulant anọ ihe.

Ịnata agwọ ọrịa na-akwalite omume hypoprothrombinemia, nke bụ n'ihi na a mebiri nke guzobere prothrombin na imeju. Nke a pụtakwara ukwu ebelata guzobere akpata 7, 9 na nke 10. Na nke a, o nwere oké mmetụta cumulated tụnyere neodikumarinom.

Ịgbaso onu ochichi, mbadamba ịta mbelata ọbara clotting ihe n'ihi na 8-10 awa. The maximal mmetụta nke ọgwụ hụrụ mgbe 25-30 awa.

Pharmacokinetics

Ọ na-etinye obi gị dum n'ime systemic mgbasa ọgwụ "Fenilin"? Ọbịa ọkachamara na-ekwu na n'ihi na nke a ọgwụ e ji a zuru ezu na zuru ezu ngwa absorption. Ya nọ n'ọrụ mgwa penetrates na histo-hematic mgbochi a na-akpọkọtara na arọ.

The ọgwụ na-metabolized na imeju na-na akụrụ ewepụtara site (dị ka metabolites na unaltered).

Egosi maka ojiji

Gịnị bụ nzube kenyere "Fenilin" mbadamba? Nyocha ọkachamara na-akọ na a ọgwụ na-eji maka ọgwụgwọ na mgbochi. Isi na-egosi maka nnabata na-thrombosis, thrombophlebitis, thromboembolic nsogbu mere site embolic ọrịa strok na myocardial infarction, nakwa dị ka otu imebi.

Ke adianade do, akuko ọgwụ mgbe kenyere mgbochi nke thrombosis mgbe ịwa ahụ.

contraindications

N'okpuru ihe ọnọdụ onye ọrịa a machibidoro iwu na-ọgwụ ọjọọ, "Fenilin"? Ntuziaka maka ojiji dị ka ndị na-esonụ contraindications:

• ụfọdụ n'ime akụrụ na imeju na;
• mbụ larịị nke prothrombin 70%;
• ụba vaskụla permeability;
• hemorrhagic diathesis na ọrịa ndị ọzọ metụtara na a gụnyere ya ná ọbara clotting;
• ọnyá ọrịa nke digestive tract;
• ịza aza neoplasms;
• pericarditis.

Anyị nwere ike ikwu na-ewere ọgwụ na-adịghị akwadoro maka ojiji na mmalite nke afọ ime n'ime ụbọchị ole na ole mgbe na-amụ nwa na mgbe nanso.

Drug "Fenilin": ntuziaka maka ojiji

E lee ya anya agwọ ọrịa were naanị maka onu ochichi. Ya ọgwụgwọ Usoro nwere ụfọdụ njirimara, na njikọ na nke a ọgwụ ga-enwe na dọkịta iwu.

The mbụ kwa ụbọchị dose bụ na-emekarị 0,11-0,17 g (4 otu dose). N'echi ya, ego nke ọgwụ na-ebelata ka 0,08-0,14 g, na ọzọ 0.02-0.05 Mgbe nke ahụ gasịrị, na onunu ogwu nke mbadamba bụ dabere na larịị nke prothrombin ke iyịp.

Karịa ego nke ọgwụ na a oge kwesịrị 0,05 g na kwa ụbọchị - banyere 0,2 grams

N'ihi mgbochi nke thromboembolic nsogbu dị mkpa na-0.03 g nke ọgwụ kwa ụbọchị site nkerisi dose ọkara.

Agwọ nke nnukwu thrombosis achọ ọzọ ndibọbọ heparin. Nke a na-achọ ike nlekota oru site dọkịta, nakwa dị ka Ịhazi amụ manye ego nke prothrombin n'ime ọbara na ihe ndị ọzọ na ya clotting.

Ọgwụgwọ na "Fenilin", analogues nke anyị ga-depụta n'okpuru, na-akwụsị nwayọọ nwayọọ.

mmetụta

Ò mmetụta nke ọgwụ "Fenilin"? Method ojiji na onunu ogwu nke ọgwụ ga-nditịm hụrụ. Nke a bụ n'ụzọ bụ isi n'ihi na eziokwu na n'oge ọgwụ, onye ọrịa nwere ike a dịgasị iche iche nke nfụkasị Jeremaya dị ka afọ ọsịsa, ọgbụgbọ na ịba ọcha n'anya. Ọzọkwa, dị ka ndị dọkịta na ndị ọrịa, na obere okwu, e nwere isi ọwụwa, ahụ ọkụ, mgbanwe na mmamịrị agba na akpụkpọ nsogbu na hematopoiesis.

Mgbaàmà nke ovadozu

Bụrụ na nke ovadozu, ọrịa nwere ike njọ mgbaàmà nke na-mmetụta. Dị ka ọgwụgwọ nke ọnọdụ ndị dị otú na-achọ amanyere bụ iwu mwepụ nke ọgwụ, nakwa dị ka ozugbo intramuscular nlekọta "menadione" oru rutin ma ọ bụ vitamin P, chloride, ascorbic acid, calcium na-ejide general symptomatic ọgwụ.

Drug mmekọrịta "Fenilin" nkwadebe

Site na ihe na-kenyere bụ ụzọ anyị tụlere n'elu. Ka anyị na-atụgharị ihe ọmụma.

Mgbe jikọtara na-ewere ọgwụ ọjọọ, "Heparin", salicylates, "Qi-metidinom" na sulfonamides nwere ike Noa ha anticoagulant mmetụta. N'ihi ya dịkwuo arụmọrụ nke "fenilina" nwere ike anabolics, "allopurinol", "Azathioprine" narcotic analgesics "Amiodarone", tricyclic antidepressants, ọgwụ nje, gluco-corticosteroids, androgens, "Diazoxide," "Dizopiramid" "Inh", " Phenylbutazone, "" Metronidazole "," Klofib-oke "," Alpha-tocopherol "," reserpine "," quinidine "" paracetamol "," Disulfiram "," Cyclophosphamide ", na thyroid homonụ.

Ịrịba attenuate ihe nke phenindione bụ vitamin K "propranolol", ascorbic acid, pụtara alkalizing mmamịrị "Rifampicin" antacids "phenazone", "Haloperidol", barbiturates, onu gbochie afọ, diuretics, "meprotan", "Carbamazepine" na " cholestyramine. "

kpọmkwem na-atụ aro

C ịkpachara anya na ọgwụ a na-kenyere ka agadi ọrịa na ndị na-akpa ume embolism, imeju na ọrịa akụrụ, erosive na ọnyá ọrịa nke eriri afọ tract, na ọbara oge, na pericarditis.

Ọgwụgwọ "fenilina" kwesịrị n'okpuru pụrụ iche na-elekọta nke a dọkịta na a amanyere bụ iwu Ịhazi ọmụmụ ọbara na ego nke prothrombin na ndị ọzọ na coagulation ihe. Ọzọkwa jide general mmamịrị ule n'oge nchọpụta nke hematuria.

Na ụfọdụ ndị ọrịa, na-oriri nke ọgwụ pụrụ hụrụ mmamịrị staining pink na n'ọbụ aka - na oroma. Nke a bụ n'ihi na metabolism phenindione.

Drug "Fenilin": ogbo na-eri

Isi echiche analogues mmadụ bụ ọgwụ ọjọọ ndị dị ka "Varfapeks" "Marevan", "neodikumarina" et al.

Ịzụta ọgwụ "Fenilin" 20 mbadamba nwere ike ịbụ n'ihi 120-140 rubles.

Nyocha na ọgwụ

Ma ọgwụ dị irè "Fenilin"? Nleba banyere nke a ọgwụ bụ nnọọ iche iche. Dị ka ha na-akọ, nke a na ngwá ọrụ bụ otu n'ime ndị kasị dị irè na ngwaahịa na nyere aka melite ọbara ọnọdụ.

N'ihi ọgwụ nke coagulation parameters na ọtụtụ ndị ọrịa laghachi nkịtị. Ọ kwesịkwara kwuru na dị nnọọ a izu mgbe mmalite nke ọgwụgwọ ọrịa kwuru mma n'ozuzu ọnọdụ. Nke a eliminates ụkwụ nkụnwụ, cramps nwoke kwụsị ichegbu onwe anyị.

Dị ka omume na-egosi na, na ụfọdụ ndị ọrịa, mgbe na-ewere mbadamba nkume "Fenilin" Ugboro nosebleeds. Otú ọ dị, dị ka dọkịta, mgbanwe ndị dị otú bụ norm. Mgbe a ọgwụgwọ, ihe niile nkịtị.

Ke adianade na-ekwurịta irè nke ọgwụ, nwere ike zutere na akụkọ nke ọrịa na a ọgwụ na-counterfeited. Ya mere, mgbe ịzụrụ bụ mgbe a n'ihe ize ndụ ịzụta a adịgboroja ọgwụ. Iji zere ndị dị otú ahụ ihe merenụ, ịzụta ọgwụ ga na-enwe obi pharmacies na-enwe ezi na-atụ aro.