Hypovarianism, Mgbaàmà na Ọgwụgwọ

N'okpuru ovarian hypofunction pụtara adakarị okwu ahụ na-agụnye ọrịa ndị dị iche na etiology na pathogenesis. Ha niile nwere yiri ihe ịrịba ama nke mmekọahụ underdevelopment. Ndị a gụnyere infertility, hypoplasia, amenorrhea, hypoestrogenism na erighị akpanwa na ovaries.

E nwere ọtụtụ ụdị nke isi hypofunction. Primary, bụ isi, na-adakarị ụdị nsogbu bụ akaghi menopause. Na-emekarị ya emee nwanyi okenye karịrị afọ 35. The etiology nke ọrịa na-egwu a isi ọrụ dị iche iche oghom gburugburu ebe obibi ihe. The akpata nsogbu nwere ike a mkpụrụ ndụ ihe nketa mutation, a mkpụrụ ndụ ihe nketa pụrụ ịrịa, autoimmune ọrịa na ovaries.

Ovarian hypofunction nwere ike ime megide a ndabere nke nkịtị ịhụ nsọ na ịmụ ọmụmụ ọrụ. Ọ na-egosipụta onwe ya n'ụdị na-ekpo ọkụ mgbukepụ, amenorrhea, mụbara sweating, ike ọgwụgwụ, adịghị ike, ihe mgbu na obi na isi, na-ebelata arụmọrụ. N'oge omume nke aghara na-kọwaa: ahụ belata size nke akpanwa na ovaries, ala kasịnụ nke estrogens na prolactin, ọ dịghị follicles odo ozu, elu follicle na-akpali akpali na luteinizing homonụ na ọbara. Nke a hypovarianism nwere ọgwụgwọ dị otú ahụ: ngwa nke homonụ (estrogen na estrogen-progestin). Mmiri ọgwụ ọgwụ ukwuu mma na ọnọdụ nke ndị ọrịa, ya mere, guzosie ike nchoputa ọ dị mkpa ka na-amalite usoro ọgwụgwọ ozugbo.

Dịpụrụ adịpụ (nke abụọ) hypovarianism, organic na ọtọ-anaghị ekwe nke ịrụ ọrụ nke hypothalamic-pituitary usoro ndị dị mkpa na-adakarị forms dị otú ahụ n'isi. N'agbanyeghị eziokwu na ndị ovaries kwuru nnọọ nkịtị nọmba nke follicles, ha adịghị eme maturation usoro. N'ihi na ndị dị otú ahụ a ọnọdụ ji: nri, bụ isi ma ọ bụ nke abụọ amenorrhea, eriri akpa nwa na ovarian hypoplasia, gipoestrogeniya. Nke a hypovarianism emekarị emee na ndabere nke nkịtị ọdịnaya nke FSH na luteinizing hormone ke iyịp.

E polycystic ovary syndrome. Nke a na ọrịa na-emetụta banyere 3% na-eto eto ndị inyom. Ndị dị otú ahụ a aghara ji ngafe mmepụta nke androgens (adrenal na ovary), elu ọdịda ha metabolism. Tinyere ihe ndị a atụmatụ ọ na-ekpebisi ibu luteinizing hormone, nkịtị ma ọ bụ ala kasịnụ nke FSH, elu ọbara etoju nke prolactin. Nke a hypovarianism, mgbaàmà ji mmepe pseudohermaphroditism, n'ihi na nke ji hyperandrogenism, clitoral hypertrophy, amenorrhea, infertility, anovulation na oké otutu.

Ọzọ mere, nke nwere ike ime n'ihi na hypofunction nke ovaries nwere ike virilizing ovarian etuto ahụ. Akpụ mkpụrụ ndụ na ovaries na-etolite oké ichekwa testosterone, dehydroepiandrosterone na androstenedione, nke bụ nwoke mmekọahụ homonụ. Clinical ngosipụta nke ọrịa bụ na-anọghị nke ịhụ nsọ, oge ufodu nanso obere (oligoopsomenoreya), acyclic eriri akpa nwa ọbara ọgbụgba. The ọrịa e ji mgbaàmà nke alopecia, hirsutism, anyịnwa ịhụkwu nke olu, guzobe nke nwoke ahụ ụdị, e guzobere pseudohermaphroditism, hypertrophy nke nwanyi ji anyu mmamiri.

Ọ bụrụ na e hypovarianism, ọgwụgwọ mgbe a saa mbara nnyocha e mere. Ke kpụworo etuto ahụ rụrụ iji ọgwụ, radieshon na ịwa ahụ mwepụ nke ngwọta. Mmiri ọgwụ ọrịa na-emeso mgbe a nyochaa nke dị iche iche homonụ.