Ọgwụ "Aspekard": ntuziaka maka ojiji, analogs, reviews

Acetylsalicylic acid (ASA) na-ezo aka ọgwụ ọjọọ eme ihe na antipyretic, mgbochi mkpali na antiplatelet mmetụta. Na ọgwụ omume ọ na-eji ihe karịrị 125 afọ, n'ihi na bụ otu n'ime ndị kasị na-amụ ọgwụ ọjọọ. Ebe ASA dị ugbu a dị ka a kardioformy iji belata ihe ize ndụ nke ịrịa akwara thrombosis, nke na-egbochi mmepe nke myocardial infarction. Otu ihe atụ bụ nkwadebe "Aspekard" nke nwere acetylsalicylic acid na a dose ezigbo maka antiplatelet mmetụta.

Ozi na ntọhapụ ụdị na Manufacturer

The emeputa nke ọgwụ bụ Ukrainian ụlọ ọrụ "Stirolbiopharm". Ntem, n'ichepụta technology mee, na-emepụta ụdị zheludochnorastvorimoy forms na a dose nke 100 mg kwa mbadamba. Ụzọ mbadamba layout:

• katọn 120 mbadamba (10 12 blisters tab.);
• polymeric akpa 100 mbadamba.

Tablet "Aspekard" dere 100 mg nke ASA, microcrystalline cellulose, croscarmellose sodium, colloidal sịlịkọn dioxide, stearic acid.

Aro maka ịhọpụta

Na nkwadebe "Aspekard" ngwa dị warara ezu, ọ bụ ezie na ọ nwere ntuziaka maka ikwu maka ọgwụgwọ nke ọtụtụ ọrịa, gụnyere rheumatic ọrịa. Emeputa na-atụ aro "Aspekard" na dị ka onye na antipyretic gị n'ụlọnga ma ọ bụ analgesic. N'ezie, na onunu ogwu nke acetylsalicylic acid na nkà mmụta ọgwụ nwere ike na-irè ji dị ka a ọgwụ na-egbochi platelet aggregation.

Egosi "Aspekard"

On nkwadebe "Aspekard" ntụziaka na ngwa, reviews adakarị nnyocha ndị ọkachamara na-enye ọtụtụ ihe ọmụma metụtara antiplatelet ọgwụ. Ọ na-owụt ke esonụ ọnọdụ:

• mgbe (ACS), nnukwu akwara syndrome (na nzọụkwụ nnukwu elu myocardial infarction, ịda mbà n'obi ma ọ bụ na-emebibeghị ST nke ọnọdụ, na-ejighị n'aka rịaworo);
• na ọrịa strok (ischemic ọrịa strok ma ọ bụ na-akwụsị akwụsị ischemic agha);
• bụrụ na nke pụtara akwara akwara ọrịa ihe dị ka ụzọ nke mgbochi nke nnukwu akwara syndrome na strok;
• na mgbochi nke ntighari ngosipụta nke nnukwu akwara syndrome na strok;
• na ọnụnọ nke varicose veins;
• dị ka a mgbochi gị n'ụlọnga, a ịdọ aka ná ntị shunt thrombosis mgbe CABG;
• na ọbara mgbali na ikpe nke a elu obi n'ihe ize ndụ.

High obi n'ihe ize ndụ bụ ihe nchịkọta echiche na-agụnye ọnụnọ nke lekwasịrị ngwa mmebi ke ọbara mgbali na metụtara ọrịa:-arịa ọrịa shuga mellitus, akwara akwara ọrịa, TSVB.

Atụmatụ onunu ogwu regimens-atụ aro ndị emeputa

Na nkwadebe "Aspekard" emeputa ntụziaka bụghị isi ochichi nke ọrịa na ọgwụgwọ. O nwere ihe ọmụma banyere ochichi nke ọgwụ na dị iche iche na-adakarị ọnọdụ sitere na site mgbochi nke atherothrombotic ihe na CHD na TSVB na-agwụcha na nnukwu ọrịa nke ụbụrụ mgbasa na n'obi. Nke a omission a na-ewere eleghara na unprofessional àgwà ndị nke nke ọgwụ ọjọọ na ha soro ozi ihe. Ọ na-emepụta na preconditions maka uka n'akwụkwọ nke isiokwu nke na-atụ aro Dosages iche.

Dosing regimens na ndabere nke mba na-atụ aro

Na ndabere nke mba ụkpụrụ nduzi mepụtara site na European Community of Cardiology (ESC) na American Heart Association (AHA) na-emegharị site Ministry of Health, na ụdịdị nke ngwa nke acetylsalicylic acid ndị dị ka ndị:

• na nzọụkwụ mberede n'oge nnukwu akwara syndrome a chọrọ inye onye ọrịa na-ata mbadamba nkume 3 "Aspekard 100". Ntuziaka maka oji a ileghara anya, na otu dose nke 300 mg;
• adịghị ala ala gbasara obi ischemia (CHD) at mgbe nile n'ikuku kenyere otu mbadamba nkume nke 100 mg na mgbede mgbe nri abalị;
• na ọbara mgbali ọrịa a elu n'ihe ize ndụ nke obi nsogbu, nakwa dị ka venous varicose mgbe niile nakweere 100 mg (1 mbadamba) na mgbede mgbe nri abalị.

Ụzọ ndị ọzọ ọgwụ ọjọọ nlekọta "Aspekard" ntụziaka ESC na AHA adịghị enye. Ọ dịkwa mkpa iburu n'obi na ọkọlọtọ dose "Aspekard" bụ 100 mg nke ASA. N'ihi mgbochi nke n'elu ọrịa, dị na ntụziaka ESC na AHA, etinyere dose of 75 mg. Otú ọ dị, 100 mg kenyere ọrịa mgbe CABG iji gbochie thrombosis nke shunt. N'ọnọdụ ndị ọzọ na ọ na-atụ aro ime 75 mg, i.e. ego nke ASA, nke na-enye zuru ezu antiplatelet mmetụta na nwere a kacha nta ize ndụ gastrotoxicity.

Ọzọkwa, ndị na-emepụta adịghị enye ihe ọmụma dị mkpa na-ekpochapụ nke ọgwụ. Dị ka ọnụ ọgụgụ, na mberede cessation nke kpatara 10.2% nke nnukwu obi ihe. Ha na-hụrụ mgbe ihe dị 10.6 ụbọchị site na ụbọchị nke kagbuo ASA. Oge a bụ nkezi na-egosiputa oge na nke ndị nile bi na-ebelata platelet cyclooxygenase ịrụ ọrụ. N'ihi ya, na o egbochi mkpụkọ nke ọbara weghachiri eweghachi. N'ihi na ọgwụ ga-a nọgidere, mgbe nhọpụta nke ọzọ antiplatelet gị n'ụlọnga kama "Aspekard" ọdịdị nke nsogbu si eriri afọ tract a chọrọ.

Contraindications "Aspekard" nkwadebe

Nchekwa nke niile na-emepụta ọgwụ na ngwaahịa bụ ikwu, n'ihi na ha nwere mmetụta. N'otu oge ha ime ka ụfọdụ contraindications. Akpan akpan:

• na-anaghị ekwe ọbara coagulation (hemorrhagic diathesis, hemophilia A na B);
• na-anaghị ekwe nke afo atụmatụ (erosions, nnukwu ọnyá nke afo na duodenum 12);
• ke akpa trimester nke afọ ime na lactation;
• na oké gbasara akụrụ ma ọ bụ hepatic impairment;
• mgbe nfụkasị Jeremaya ka salicylates;
• na ụmụaka na-erubeghị afọ 18,;
• na ọnụnọ nke bronchial ụkwara ume ọkụ;
• na ọgwụgwọ nke methotrexate.

Ndị a contraindications bụ zuru, ọ bụ ezie na ụfọdụ oge: lactation, afọ ime, ozize na ọnyá nke eriri afọ tract, na nwa ọhụrụ. Na-enwere a otu nke na-ekwu, ọnụnọ nke nke na-achọ mgbe nile na nlekota oru site a dọkịta. Nke a n'otu oge ojiji nke antiplatelet ọgwụ na anticoagulants, na ọgwụgwọ nke ọrịa mgbe akwara akwara wasịrị. Ọ bụrụ na akụrụ ọrụ etinyere ọgwụ "Aspekard" ntuziaka maka ojiji na-achọ usoro onunu ogwu Mbelata ma ọ bụ mezue gradual abolition nke ọgwụ.

Joint mmetụta "Aspekard"

Acetylsalicylic acid nwere ọtụtụ mmetụta na welie ma ọ bụ akụda ihe nke ọtụtụ ọgwụ ọjọọ. Akpan akpan:

• ASA enhances mmetụta nke ọ bụla anticoagulants na antiplatelet mmadụ;
• ASA enhances antipyretic na analgesic utịp NSAIDs, amplifies antirheumatic mmetụta "Meloxicam";
• mgbe jikọtara na cytotoxic ọgwụ ọjọọ enhances ha gastrotoxicity;
• mgbe a na-na-aba n'anya na ihe ize ndụ nke ọnyá afọ nsogbu ma ọ bụ ọbara na-agba na-abawanye;
• glucocorticoids abawanye gastrotoxicity "Aspekard";
• ACK attenuates mamịrị mmetụta mgbe jikọtara na diuretics "Furosemide", "torasemide", "spironolactone".
• "Aspekard" ebelata mmetụta nke uricosuric mmadụ, "Probenecid", "Etamid", "sulfinpirazon";
• nonabsorbable antacids budata belata absorption nke "Aspekard".

The puru ịṅụfe ọgwụ ike ókè na ya mgbaàmà

Dịtụ ọgwụ "Aspekard" ntụziaka, nzaghachi na ojiji nke ọnụ ọgụgụ na-akwado a elu nke ọma larịị nke nche na n'ikuku dị ka ndị na-egosi na contraindications wezụga. Nke a pụtara na e kenyere dose of 100 mg nke ọgwụ bụ nchebe ezu, ọ bụ ezie na akara nke ala nke ahụ ike dị mkpa. Ọzọkwa, nke ìgwè ndị agha nke ọrịa na igbu onwe, nakwa dị ka ihe ize ndụ na mbadamba nkume nke ASA ga-nwa, zuru ezu chọrọ puru ovadozu na ya mgbaàmà.

Nwayọọ nsi salicylates, iwe na ngwa nke nkwadebe "Aspekard" na-enweghị a dọkịta na-atụ aro mgbaàmà ndị na-esonụ na-ekwu: dizziness, ihe mgbu na fossa podlozhechkovoy, alọ ebe, mgbe ụfọdụ, ihe mgbu, karịsịa na ọrịa na ọrịa akụrụ. Bụrụ na nke ovadozu dị ka e nwere na-ama jijiji, na-agbọ, mgbe ụfọdụ, na ọbara streaks. Nke mbụ bụ site wuru itinye n'ọkwa nke emesis: ukwuu ọṅụṅụ jụrụ oyi, rụọ ọrụ unyi usoro na ehnterosorbentov nnyefe ndidi na a ọgwụ.

Ihe, ndị na-egbu egbu doses "Aspekard" ntụziaka ntuziaka anaghị ezipụta. Ha na-dị iche iche maka iche iche ibu na afọ nke onye ọrịa. Ihe atụ, na ihe okenye mmadụ ovadozu nwayọọ mgbaàmà ASA ime na otu mbanye banyere 5-7 grams acid. Children nwere ezuru ihe ovadozu nke 1.5 g otu dose. A bukwanu ovadozu na-adị mgbe itinye 7-9 grams nke ndị okenye na ụmụaka 2-2.5 gram ASA.

Nke a ogo ọgwụ ovadozu egosipụta site n'elu ọrịa metụtara cognitive ọrụ. Echefuola dee amalite tinnitus echiche na-mgbagwoju anya, incoherent okwu. Vomiting na-eme, onye ọrịa ngwa ngwa tụfuru ọmụmụ site vomiting, iku ume quickens, e nwere nnukwu urinary njigide, mụbara ahu okpomọkụ. Inyere onye ọrịa na ọnọdụ dị otú ahụ ọ gaghị ekwe omume onwe - nnyefe na-chọrọ ke NICU maka infusion ọgwụ bicarbonate, sodium lactate.

Akụkụ nke ọgwụgwọ edinam "Aspekard"

Mmasị ka ọgwụ ọjọọ, "Aspekard" na-arụ ọrụ ntụziaka mejupụtara anata ihe na-egosi otu mbadamba kwa ụbọchị (100 mg / ụbọchị). Nke a dose ASA bụ zuru ezu nke ibelata platelet cyclooxygenase. N'ihi bụ mgbochi nke njikọ nke thromboxane A2, nke kpamkpam na-egbochi ikike nke mkpụrụ ndụ platelet aggregation. Nke a eliminates ekwe omume nke thrombosis, nke bụ ihe na-akpata myocardial ma ọ bụ ọrịa ụbụrụ infarct.

Iji nye antithrombotic mmetụta nke acetylsalicylic acid a ga-etinye obi gị dum n'ime ọbara. Otú ọ dị, ụfọdụ nke ọ na-eme na afo na kwa inhibiting cyclooxygenase-1 na ya isoforms na mucosa nke ngwa. The N'ihi nke a na usoro bụ akụkụ mmetụta - belata ike muco-echebe ihe mgbochi carbonate. A na-enwekwu ihe ize ndụ nke erosions na ọnyá nke afo, akpali eriri afọ-ọbara ọgbụgba. Enteric formulations nwekwara ike ime ka ọbara na-agba, kama ugboro nke a n'akụkụ mmetụta, ha nwere nnọọ obere.

Pregnancy na lactation

Expert uche, dabeere na mgbakọ na mwepụ nwale na a usoro nke nwere, ekwe ka ị na-enwe a nghọta doro anya nke ngwa nke "Aspekard" ọgwụ mgbe ha dị ime. Karịsịa, 1 trimester amachibidoro ya. Na 2 na 3 trimester ngwa na-kwere, ma mgbe nwale nke ya ọgwụgwọ were na atụnyere n'ikuku ize ndụ. Na ọgụgụ ka ukwuu nke na-adakarị ọnọdụ oru ASA isi, ọ bụ ezie na ndị ọzọ NSAIDs nwekwara ike dịkwuo ize ndụ nke ime ọpụpụ.

N'oge lactation, iji ọgwụ "Aspekard" analogues ya, generics, nakwa dị ka ihe niile ọgwụ na acetylsalicylic acid na mejupụtara ajuru aju. Ihe kpatara nke a bụ see ọgwụ na mmiri ara. ya penetrates ọbụna na ya na nwa ahu. Na ya ize ndụ bụ elu n'ihe ize ndụ nke na-emepe emepe Reye si syndrome - nnọọ oké hepatic encephalopathy, nke na-akpata ụbụrụ ọzịza na ọnwụ nke a nwa. N'otu aka ahụ, machibidoro ojiji nke ọgwụ tupu afọ nke 16-18 afọ.

Nkọwa Nyocha ọkachamara na ndị ọrịa

Ihe e ji mara ọgwụ "Aspekard" ndidi nzaghachi na ọtụtụ mgbe na-abụchaghị eziokwu. Ha ghaghị enyocha ihe price nke ọgwụ, ebe ọ fọrọ nke nta nke kasị ala n'etiti ọgbọ. Otú ọ dị, na-ekwu metụtara ndị bara uru ngwa nke obere indicative nke enweghi ike itule ogo nke omuma ọrịa belata ihe ize ndụ nke vaskụla thrombosis. Na usoro nke mmetụta kọrọ site ọrịa, ọgwụ e ji dị ka zuru ezu dị mma.

Echiche ndị ọkachamara na ndị doro anya: apụ, ọgwụ dị irè na mbenata ihe ize ndụ nke thrombosis, na abuo, ọrịa Ikwenyesi antiplatelet ọgwụ bụ elu n'ihi na nke ala "Aspekard" price nke ọgwụ. Analogs nke klas nke antiplatelet mmadụ bụ budata elu. Domestic enteric nkwadebe "Atsekardol" ihe dị oké ọnụ site na 50%, mgbe ndị na-eri bubata elu site 7-10 ugboro. Ma dabere na ole na ole mmetụta enteric mmadụ, nakwa dị ka akụ na ụba Nchoputa, ọ na-achọsi ike na-enye mkpa "Atsekardolu". The na-eri nke ọnwa ọgwụgwọ ga-banyere 20 rubles.

The ebumnobi enweghị kardiopreparata "Aspekard"

Mmasị ka ọgwụ ọjọọ, "Aspekard 100" ntụziaka ntuziaka na-ekwu na ọgwụ dị na mbadamba. Ha igbari ke afo na-emepụta a akwa ịta. Inye obodo gastrotoksichesky mmetụta, ọgwụ na-efunari Safety Other ọgwụ ọjọọ, ya bụ enteric. gastric ọbara ọgbụgba n'ihe ize ndụ mgbe n'itinye ikpeazụ nnọọ obere.

Ihe Nlereanya nke odi mfe ọgwụ ndị dị ka ndị a: "Atsekardol", "Polokard", "Cardiomagnyl", "Ọgwụ Aspirin Cardio." Ọzọkwa, kwuru, sị n'aka nwekwara nkejikotara magnesium hydroxide, ike chebe mucosa mmerụ site acetylsalicylic acid. O sina dị, ọgwụ "Aspekard" mee ihe mgbochi nke thrombus guzobere, albeit na mgbochi. Otú ọ dị, ọrịa na-enwe mucosal ozize, ọnyá afọ 12 duodenum ma ọ bụ na afo, gụnyere-adịghị ala ala, ọ na-atụ aro na-enteric kardioformy acetylsalicylic acid.

Vneotraslevoe ngwa kardiopreparata "Aspekard"

Ọtụtụ n'ime ndị dị ntuziaka maka ojiji na-egosi na ọnụnọ antiinflammatory na antipyretic Njirimara ọgwụ "Aspekard 100". N'eziokwu, full-agwọ nwere ọgwụgwọ mmetụta bụ 5 ugboro otu dose - 500 mg. The onunu ogwu nke 100 mg bụ nanị gbasara obi, na mmetụta ya nke ọma bụ zuru ezu n'ụzọ dị irè belata okpomọkụ na-efe efe.

Kardioforma nkwadebe arụpụtara ke a dose of 100 mg, adabara mgbu na fever enyemaka naanị na otu dose of 5 mbadamba. N'ihi ya predominance selectivity maka cyclooxygenase 1 ekpebi ọnụnọ nke a plurality nke n'akụkụ Jeremaya mere. Ya mere, dị ka a febrifuge "Aspekard" mkpụrụ ọgwụ, n'ezie, ndị kwesịrị ekwesị. Otú ọ dị, ugbu a na e nwere ọtụtụ a ọnụ ọgụgụ nke dị nchebe karị ọgwụ ọjọọ na-egosi ukwuu selectivity maka cyclooxygenase 2. Ha nwekwara ole na ole mmetụta jikọtara ndị mebiri nke proliferation nke eriri afọ epithelium.

Safety klas ogbo "Aspekard" ọgwụ

A yiri emekarị chọpụtara na ọgwụgwọ nke rheumatic ọrịa. Na mmasị ọgwụ "Aspekard" ntụziaka maka ojiji e dere ozi banyere ha ọgwụgwọ. Otú ọ dị, na-atụ aro dose bụ nke iji nke 5-8 grams kwa ụbọchị.

A ego nke acetylsalicylic acid egosi gastrotoxicity akakamade ike imetụta mmadụ karịa mgbe "meloxicam" Pharmaceuticals, "celecoxib", "Roferoksib" na ndị ọzọ. Na dị ka antipyretic kasị baa uru klas analogue bụ "Ibuprofen".