"Pentoxifylline": analogues, ntuziaka maka ojiji, n'ezie ahịa

The ọgwụ nwere ike dochie anya "Pentoxifylline?" An analogue nke ọgwụ ga-adade ke isiokwu ihe. Site na ya, ị ga-amụta ihe a pụtara, sị agwọ ọrịa forms na nke ọ na-ere ere, otú ọ ga-eji, na na.

The mejupụtara, udi, nkwakọ

Na ihe n'ụdị na-eresị ọgwụ "Pentoxifylline?" Ntuziaka maka ojiji (analogues nke a ọgwụ nwere ike dị na bụla ahịa ọgwụ ahụ) na-egosi na nkà mmụta ọgwụ dị na iche iche iche iche, ya bụ:

• Na mbadamba (400 na 100 mg) na-ntekwasa pink. Na otu katọn nwere ike ịnwe 60 ma ọ bụ 20 iberibe.
• The pellets (400 na 100 mg). The audio mkpọ katọn nwere ike 60 ma ọ bụ 20 iberibe.
• Na mbadamba, na ruo ogologo oge edinam (600 na 400 mg) na-ntekwasa na enteric-ntekwasa nwere a akara maka nkewa. The nkwakọ katọn emekarị nwere 50 iberibe.
• The vials na ihe ngwọta maka ogwu ogbugba. The mejupụtara nke a Nwa-agụnye pentoxifylline na sodium chloride na mmiri.

pharmacological atụmatụ

Gịnị Njirimara ka ọgwụ "Pentoxifylline?" Analogue nke a n'aka nwere otu e ji mara dị ka kwuru agwọ ọrịa naanị. Ọ bụ nke a ọhụrụ pharmacological otu hemorheological ego. Ọ bụ ike iji weghachi plasticity nke mkpụrụ ndụ ọbara uhie ma belata ha deformation. A na-enwekwu ndị permeability nke ọbara arịa, nke nwere a warara lumen.

A Njirimara nke ọgwụ na-eduga ná mma microcirculation, mmetụta dị mma na anụ ahụ hypoxia.

Olee otú "Pentoxifylline?" Analogues nke mbubata na Russian nwere otu ọgwụgwọ mmetụta dị ka nke ego onwe ya. Mgbe ojiji nke ọgwụ, ọ na-ebelata aggregation nke erythrocytes nke ekemende mfe mụbaa ọbara eruba akụkụ na banye n'ime n'ime extravascular direction.

Anyị enweghị ike ikwu na-ewere ọgwụ na-ebelata ọbara viscosity, si otú na-akwalite platelet disaggregation. Dị ka a n'ihi nke mmetụta nke ọgwụ na-ụba nkeji na strok olu, ma ọ dịghị agbanwe agbanwe obi ọnụego ọgụgụ.

N'ihi ya, akpa ume mgbasa arịa mma O ₂ ọdịnaya nke ọbara, na mmụba nke akwara akwara ntọt O ₂ nnyefe na myocardium.

E lee ya anya Nwa ike nke na-amụba ụda nke akụkụ okuku ume uru na diaphragm. Mmụọ enwekwu ego nke ọbara na-abanye collaterals, nakwa dị ka enwekwukwa ọbara na ha.

Gịnị ọzọ na atụmatụ nke ọgwụ nwere "Pentoxifylline?" Analogue nke a ọgwụ na ọgwụ na ya dịkwuo ịta nke ATP na ụbụrụ na-melite inweta ọbara ahụ mebiri emebi na mpaghara (e.g., na ischemic ọrịa strok).

Ọ kwesịkwara kwuru na kwuru ọgwụ nwere a nti mmetụta na Central ụjọ usoro na-arụ ọrụ. Na ọnya nke elu akwara eji nke a pụtara na-eduga na-amụba na-eje ije anya, gụnyere na ọrịa ndị dị ka obliterative endarteritis.

pharmacokinetic parameters

ọgwụ ọjọọ, "Pentoxifylline" Olee otú anya? Ntuziaka maka ojiji (analogues nke a na nkà mmụta ọgwụ e depụtara n'okpuru ebe) na-agwa anyị na a ọgwụ nwere magburu onwe abami ike, gụnyere site na ọbara-ụbụrụ mgbochi.

The ọkara ndụ nke ọgwụ mgbe ndinọ intravenously bụ 30 nkeji. Mgbe anata ọgwụ n'ime ya kpamkpam etinye obi gị dum na eriri afọ tract.

Agwọ ọrịa gbanwee imeju, ebe ọ Nleta metabolites theobromine. The kacha ọbara ịta nke ọgwụ a na-enweta n'ime 4 awa mgbe ngwa. Otú ọ dị, ọ na-anọgide na ọgwụgwọ etoju banyere a ụbọchị.

Egosipụta agwọ ọrịa na akụrụ (ihe dị ka 95%). eriri afọ site ọgwụ si ubé.

Mgbe fairer mmekọahụ onye breastfeed, ọgwụ nwere ike wepụtara na ndị mmiri ara ehi. Ọ kwesịkwara kwuru na mkpochapu nke ọgwụ slowed na ọrịa na oké ọrịa akụrụ, imeju na-na na ndị agadi.

Egosi maka ojiji

N'ihi na ihe na nzube onye ọrịa nwere ike-kenyere ọgwụ "Pentoxifylline?" Analogs na ọgwụ ndị nọ n'ọnọdụ nwere otu na-egosi.

Ugbu a, ndị dị otú ahụ dị irè ọgwụ ọjọọ na-eji na-emeso ọtụtụ ọrịa. N'ebe a, ha na-now:

• cerebrovascular erughi;
• urolithiasis;
• arteriosclerotic encephalopathy;
• ischemic strok;
• ọrịa nefroangiopatiya;
• ọbara mgbali;
• okpo bronchitis;
• bronchial ụkwara ume ọkụ;
• elu ọbara ọrịa ;
• encephalopathy;
• algomenorrhea;
• sepsis;
• cholecystitis;
• nsia dyskinesia ;
• pilorospazm;
• ezigbo muscle spasm;
• post-trombophlebitic syndrome;
• dysmenorrhea;
• angioneyropatii (Raynaud ọrịa) ;
• ọbara ọrịa anya;
• trophic anụ ahụ ọrịa;
• trophic ọnyá;
• egwu ime ọpụpụ;
• ọtọ ọrịa nke etiti na n'ime nti;
• vaskụla enweghi ike;
• muscular dystrophy;
• ure anụ, oké oyi.

contraindications

Nke ọrịa na-egbu site n'iji ọgwụ ọjọọ, "Pentoxifylline?" An analogue nke ọgwụ na ọgwụ apụghị a n'ihi ndị na-ekweghị ibe nọrọ na isi mmiri, nakwa dị ka ndị ọzọ na-anọchite anya nke xanthine otu.

Ke adianade do, na-ewere ọgwụ contraindicated na ọrịa nwere na nso nso ahụhụ a hemorrhagic ọrịa strok ma ọ bụ nnukwu myocardial infarction nakwa dị ka na-ata ahụhụ si na oké atherosclerosis n'obi na ụbụrụ akwara, porphyria.

Igba ogwu n'akwara ọgwụ ọjọọ a machibidoro iwu n'ihi arrhythmia, ọbara ọgbụgba, ala ọbara mgbali, hemorrhages na retina. Ọzọkwa, ọgwụ na-contraindicated n'oge lactation na gestation, ụmụaka ruo 18 afọ.

Na pụrụ iche ịkpachara anya na-kenyere pụtara ejikwara ndị mmadụ (iji gbochie ọbara ọgbụgba nke mucous membranes na esịtidem akụkụ), na ọrịa na oké akụrụ na imeju, eriri afọ ọnyá afọ ọrịa, mgbu na obi ọdịda.

Ụzọ nke Iji

Olee otú iji ndị ọgwụ ọjọọ, "Pentoxifylline?" Ntuziaka maka ojiji, ezigbo (analogues nke ngwá ọrụ a nwere ike dị iche iche Dosages) nwetara na dọkịta ekwuo na a ọgwụ e ji ọnụ na na parenterally (dabere na ogo nke ọrịa).

Oral ochichi nke ọgwụ na-amalite na a dose nke 200 mg (i.e., 2 mbadamba ugboro atọ a ụbọchị, mgbe a nri). Mgbe na-eru kpọmkwem ọtụtụ ọgwụgwọ mmetụta belata ọkara. The ọgwụgwọ ọgwụ ga-adịru dịghị ihe karịrị otu ọnwa.

Na oké na nnukwu ọrịa nke esịtidem akụkụ ọgwụ ndinọ na capsules. E nwere 2 ụzọ nke ọgwụ ochichi: igba ogwu n'akwara na intraarterial. The mbụ usoro rụrụ site a dropper. N'ihi nke a, 1 mkpọ 250 ml glucose ngwọta ma ọ bụ sodium chloride. Sị na onunu ogwu na-ndinọ n'ime 2 awa.

Ma intraarterial ochichi, ọ na-ndinọ na a dose nke 0,1 g kwa 50 ml nke sodium chloride ngwọta.

mmetụta

Otu n'ime ihe ndị kasị nkịtị mmetụta ọjọọ ndị na-esonụ:

• dizziness, nchegbu, nsogbu ihi ụra, ọdụdọ, ọnọdụ mgbanwe, isi ọwụwa;
• cholecystitis exacerbation, elu imeju transaminases, mmepe cholestatic ịba ọcha n'anya;
• vomiting, mmetụta nke ozuzù na afo, ọgbụgbọ, afọ ọsịsa, na ọnwụ nke agụụ;
• aṅụ, anaphylactic ujo, itching, angioneurotic edema, nācha ọbara-ọbara nke anụ ahụ;
• omume nke arrhythmias, obi mgbu, ibelata ọbara mgbali, stenokardicheskie mgbu;
• thrombocytopenia, leukopenia;
• ulo, bịara ikiri ọhụụ;
• exacerbation nke ụkwara ume ọkụ, bronchospasm, akụkụ okuku ume na insufficiency;
• agba ọbara nke dị iche iche etiology.

Drug "Pentoxifylline": analogues, price

Analogs na-atụle ọgwụ ọjọọ ndị na-esonụ ọgwụ ọjọọ:

• dragees "Agapurin" (100 mg) na a ngwọta maka ọgwụ na ampoules (100 mg);
• mbadamba "ite", ntekwasa mbadamba (600 mg);
• dragees, mbadamba na injectable ngwọta "Trental".

Ọ ga-kwuru na "Trental" na-anọchi anya na mbụ ọgwụ. Na e kenyere ya ọrịa na encephalopathy nke dị iche iche si malite.

Ma ihe ndị price, mgbe ahụ, a niile preparations ọ bụ dị iche iche. Analogue "Trental" "Pentoxifylline" nwere ike zụrụ maka 120 rubles mbụ agwọ ọrịa - maka 520 rubles "Agapurin" - 300 rubles, ebe "ite" - 400 rubles.

Nyocha

Nyocha banyere nke a ọgwụ bụ tumadi mma. Ọgwụ bụ irè vaskụla ọrịa nke ọtụtụ akụkụ na usoro. Kasị reviews na nke "Pentoxifylline" gbahapụrụ ndị ahụ na-ata ahụhụ site na kpochapụ endarteritis na intermittent claudication. Nke a agwọ ọrịa bụ n'ihi na ha a n'aka № 1, ebe ọrịa a nēche aka inwe ọganihu.