The ọgwụ 'calcium pantothenate': e ji mara na ojiji na nkà mmụta ọgwụ

Pantothenic acid (onunu ogwu ụdị - ọgwụ "Calcium pantothenate") esịne ke otu nke vitamin B. Nke a mmanu mmanu, optically ifịk mmiri mmiri, ukwuu soluble na mmiri, na-ngwa ngwa rapara n'okpuru edinam nke okpomọkụ, asịd na alkalis.

Pantothenic acid a hụrụ na ihe oriri na-synthesized site nsia microflora (Escherichia). Mgbe absorption ọ abatakwa n'ọbara na-ebu niile akụkụ na anụ ahụ, na-edebe ke imeju, nwere obere na myocardium, akụrụ na skeletal muscle. Ke idem, ọkacha mma acid metụtara na-edozi na a akụkụ nke CoA (coenzyme A). mmebi ngwaahịa nke ọgwụ "calcium pantothenate" anyụpụ na mmamịrị na na nsị. Ọ ga-kwuru na ọnụ ọgụgụ nke ahọrọ pantothenic acid bụ mgbe karịrị nke banyere ahụ nri. Nke a bụ n'ihi ya nje njikọ.

Pantothenic acid bụ a akụrụngwa nke CoA, nke ndị mejupụtara atọ akụkụ: nke fọduru tiolamina, pantothenic acid, 3-phospho-5adenozin-5-diphosphate. CoA bụ a-eme ihe metabolism, atụ ke ịrụ ọrụ nke ndị Krebs okirikiri na ndu njikọ na ọxịdashọn nke carbohydrates, lipids, glucosamine guzobere, acetylcholine, hippuric acid, porphyrins, wdg

Drug "Calcium pantothenate" - ubé acha ma ọ bụ na-acha ọcha ntụ ntụ na a ilu uto, odorless, soluble n'ime mmiri. Okenye agbanwe agbanwe nke thermally mụ, ma ngwa ngwa gbarie mgbe ọ gụrụ acid na alkali. The ọgwụ nkwadebe na-emepụta dị ka mbadamba, ntụ ntụ na ngwọta na vials.

Ya pharmacological omume nkwadebe "Calcium pantothenate" na-egosi mgbe pantothenic acid ghọọ coenzyme A, nke na-enye beta-ọxịdashọn, ọdụdụ acid njikọ, oxidative decarboxylation, na n'ịtụgharị pyruvic acid na ketoglutaric acetyl. Ọ na-enyere ndị absorption nke glucose na eriri afọ, enwekwu larịị nke glycogen na imeju, apụta ihe na mmiri ọgwụ ọnọdụ nke organism, karịsịa n'oge ime.

Na erughi nke pantothenic acid ke idem bụ eru hormone ọrụ pituitary, adrenal gland na pancreas. The adrenal glands ebelata larịị nke steroid homonụ, nke na-enye pigmentation nke ntutu na akpụkpọ. Metabolic aghara akpalite dermatitis, anụ depigmentation. Degenerative mgbanwe hụrụ na adrenal glands na ụjọ anụ ahụ. Ha nwekwara ike ịbụ gbajiri moto nchikota, njọ ọrịa akụrụ, obi, eriri afọ na afo. The isi na-akpatara ndị vitamin erughị eru bụ ezughi oke ichekwa a vitamin na oriri, bowel ọrịa, na ruo ogologo oge iji ọgwụ nje (sulfonamides, ọgwụ nje).

Isi adakarị ịrịba ama nke a enweghị pantothenic acid ke idem - ịda mbà n'obi, ike ọgwụgwụ, ike ọgwụgwụ, ehighi ura, isi ọwụwa na ike ahu mgbu, ọgbụgbọ, afọ ọsịsa, flushing nke anụ na-akwụsị, duodenal ọnyá afọ. Na erughi nke vitamin belata immunological eguzogide nke organism. Megide a ndabere, mgbe mgbe, e nwere akụkụ okuku ume na ọrịa.

nke ukwuu mgbe, ndị dọkịta idepụta ọgwụ "calcium pantothenate" maka ụkpụrụ nke metabolic n'ibu. Nabata na kwuru agwọ ọrịa polyneuritis, paresthesia, neuralgia, bronchitis, eczema, dermatitis, Burns, trophic ọnyá, ime toxicosis, ụkwara nta, hypothyroidism, pancreatitis, gastroduodenitis, wdg Medicine "calcium pantothenate" na-anabata nke ahu. N'ihi enteral ochichi nwere ike dyspeptic mgbaàmà, site parenteral (intramuscular injection) - soreness.

Oversupply nke calcium (hypercalcemia) nwere ike ime n'ihi na dysfunction nke endocrine glands (parathyroid gland). Hypercalcemia na-aha na ndị agadi. hypercalcemia Clinic pụrụ igosipụta dị ka n'ozuzu adịghị ike, ọnwụ nke agụụ, na-mgbe ụfọdụ hụrụ cramps na afọ ntachi.