Ụkpụrụ nke complementarity: ọdịdị zuru oke nke echiche na ihe ndị bụ isi iwu nke mkpụrụ ndụ ihe nketa

Complementarity - a onwunwe bụ abụọ owuwu-ederịta akwụkwọ ozi ọ bụla ọzọ na a n'ụzọ pụrụ iche.

complementarity ụkpụrụ okụt ngwa dị iche iche na ngalaba nke mmadụ ọrụ. Ya mere, ọdịdị zuru oke nke complementarity na mmụta usoro na kpọmkwem e ji mara nke e guzobere na mmepe nke ụmụ akwụkwọ na ọnọdụ nke isiokwu nke akwụkwọ Ọdịdị. Na mpaghara nke creativity-arọ e jikọtara ya na ịma na onwu ifịk ụkpụrụ bụ a ekwekọghị gbasara ohere owuwu nke abụọ dị iche iche ụmụ irighiri ihe, nke nwere ike ime n'etiti hydrogen bonding na intermolecular mmekọrịta.

ụkpụrụ nke complementarity na usoro ndu gbasara nnabata nke biopolymer ụmụ irighiri na ha dị iche iche iberibe. Ọ ana achi achi guzobe a anya njikọ dị n'etiti ha (e.g., hydrophobic ma ọ bụ electrostatic interactions n'etiti ebubo ọtọ iche iche).

N'ihi ya na-arụkọ iberibe na jikọtara biopolymers bụghị covalent chemical nkekọ na gbasara ohere ozi ka onye ọ bụla ọzọ na-etolite na-adịghị ike njikọ nke ịgụnye nwere nnukwu ike, nke na-akpata kpụworo a zuru ezu anụ okụre nke ụmụ irighiri. Na nke a, na catalytic ọrụ bekee bụ dabere na ha complementarity na etiti catalytic Jeremaya mere.

M ga-asị na e nwekwara a echiche nke bughi ozi nke abụọ ogige. Ihe atụ, mgbe ndị intermolecular mmekọrịta nke protein complementarity ụkpụrụ - a-ekwe omume nke ligand obibia onye ọ bụla ọzọ na a nso anya na-enye a siri ike njikọ n'etiti ha.

Ụkpụrụ nke complementarity na ubi nke mkpụrụ ndụ ihe nketa na-akpata nchegbu replication (ibawanye) nke DNA. Onye ọ bụla yinye nke ihe owuwu nwere ike ije ozi dị ka a template na na-eji na njikọ nke arụkọ uzo na ikpeazụ ogbo na-enye ohere iji nweta replicas nke mbụ deoxyribonucleic acid. N'otu oge ahụ na e nwere a doro anya ozi n'etiti nitrogenous bases, ebe adenin na-ejikọ na tamin, na Gwanine - na-agakọta naanị.

Oligo na polynucleotides nitrogenous bases etolite a kwekọrọ ekwekọ ụzọ okụre - T-A (A-U na RNA) ma ọ bụ D-C site omume abụọ uzo nke nucleic asịd. Ụkpụrụ a nke complementarity keere òkè bụ isi na huu isi usoro nke nchekwa na nyefe nke mkpụrụ ndụ ihe nketa na ozi. N'ihi ya, na ibawanye nke DNA n'oge cell nkewa, na DNA na RNA transcription usoro na-ewe ebe mgbe protein njikọ rụzie Filiks (Mbelata) nke DNA mmebi mgbe ịbụ-agaghị ekwe omume na-enweghị nlere ụkpụrụ a.

Mgbe ọ bụla ụfọdụ n'ime nditịm gaghị agara ozi n'etiti mkpa akụkụ nke dị iche iche ụmụ irighiri ihe na ahụ na-enwe a daa ọrịa nke na-clinically gosipụtara mkpụrụ ndụ ihe nketa ọrịa. Ha nwere ike ibunye ndị ụmụ ma ọ bụ na-emegide ndụ.

- Ke adianade do, otu ihe dị mkpa analysis dabeere na ụkpụrụ nke komplementaranosti PCR (polymerase ihe mkpalite). Na kpọmkwem mkpụrụ ndụ ihe nketa ziri ịchọpụta DNA ma ọ bụ RNA nke dị iche iche pathogens ma ọ bụ na-efe efe malitere ịrịa ọrịa na mmadụ, nke na-enyere nye iwu ọgwụgwọ dị lesion etiology.