Ahụ ike, Ọrịa na ọnọdụ
Amyotrophic mpụta sclerosis: akpata, mgbaàmà, ọgwụgwọ
"Amyotrophic mpụta sclerosis" Disease bụ a arọ organic daa ọrịa nke na-amaghị etiology. Ọ e ji ọnya nke elu na nke ala moto akwara ozi, na-aga n'ihu N'ezie. Agwụ ALS (Amyotrophic mpụta sclerosis) invariably egbu. Ọzọ, anyị na-amụta otú na-egosipụta daa ọrịa, na ma e nwere a-ekwe omume nke igbu ndị ọrịa.
Isi
Amyotrophic mpụta sclerosis na-atụle ihe na-enweghị ngwọta ọrịa. Ọ na-emetụta Central ụjọ usoro. Pathology nwere ụfọdụ ndị ọzọ na aha: Lou Gehrig ọrịa, Louis Gehrig ọrịa, n'ihi na ihe atụ. The nchoputa bụ bụghị mgbe niile mfe. The eziokwu na-adịbeghị anya nke ukwuu ụba nso nke ọrịa dị iche iche na-adakarị ngosipụta na-hụrụ dịghị nhata dị ka ndị dị otú ahụ, na Amyotrophic mpụta sclerosis syndrome. Na nke a, taa ndị ọkachamara kweere Ọrụ kacha mkpa delineation na ukpụhọde nke ọrịa etiology.
Amyotrophic mpụta Sclerosis: Mgbaàmà
Ngosipụta nke daa ọrịa na-metụtara, bụ isi, na-emeri nke ala moto neuron. Amyotrophic mpụta sclerosis, onye mgbaàmà na-agụnye atrophy, adịghị ike, fasciculations, nwere ihe ịrịba ama nke mmebi corticospinal ọwa. Nke ikpeazụ bụ spasticity na ụba akaị na -enweghị nchịkwa na-aghọ nkọ na-enweghị sensory impairment. Na nke a, na cortico-bulbar traktị nwere ike aka. Nke a, n'aka nke ya, ga-mee ngwangwa mmepe nke daa ọrịa n'ogo nke brainstem. ALS emetụta agadi na. Pathology na-mepụtara ruo mgbe afọ 16.
egosiputa atụmatụ
Na mmadụ na-ata ahụhụ site na Amyotrophic mpụta sclerosis, mmalite nkebi nke ọrịa bụ nnọọ muscle atrophy (nwayọọ N'ezie) na hyperreflexia. Nke a na atụmatụ bụ ihe kasị mkpa na-adakarị pụta ìhè. Pathology nwere ike ịmalite na na niile striated muscle emep uta eri. Amyotrophic mpụta sclerosis nwere ike iche iche: bulbar, elu, lumbosacral na cervical-thoracic. -Akpata ọnwụ, dị ka a na-achị, ọ bụ mmeri nke akụkụ okuku ume na akwara mgbe banyere 3-5 afọ. Amyotrophic mpụta sclerosis nwere ọtụtụ ihe e ji mara atụmatụ. Otu n'ime ndị kasị ugboro ugboro ngosipụta atụle-aga n'ihu adịghị ike nke muscle emep uta eri nke onye nke elu nsọtụ. A, ọ na-amalite mgbe nkwojiaka. Na mmepe nke proximally ewekarị anụ ahụ daa ọrịa n'onwe eruba ọzọ bụ mma. Ná mmalite nke ọrịa ndị a na-mmepe nke muscle adịghị ike dị n'aka, usoro aka thenar emep uta eri. Status egosi adịghị ike adduction (iwebata) na mmegide nke isi mkpịsị aka. N'ihi bụ ihe siri ike ịghọta isi mkpịsị aka na forefinger, nsogbu ezi moto akara. Ọrịa na ALS eche ihe isi ike inserting (buttoning-ala) na atụtụ obere ihe. Ọ bụrụ na ọ na-emetụta na-achị n'aka-egosi ihe isi ike mgbe ede, eme kwa ụbọchị ke ufọk. Dịtụ mma atụle lumbosacral ụdị.
Ahụkarị daa ọrịa maka
Na nke a, e nwere a ufọk ufene, na-aga n'ihu itinye aka na usoro nke uru ahụ nke otu N'ịdị. Mgbe e mesịrị ya malitere ịgbasa na abụọ aka imeri bulbar emep uta eri ma ọ bụ ụkwụ. Amyotrophic mpụta sclerosis pụrụ ịmalite na ire mọzụlụ, ọnụ, ihu ma ọ bụ ụkwụ. Na nke a, ụdi mbibi "na-adịghị ịchụkwudo" mbụ. Na nke a, ọ na-ewere ndị kasị nso ndu ndimmadu na bulbar ụdị. Ọrịa anwụ, fọdụrụ nta na ụkwụ, ọ bụghị na-eche ala N'ịdị mkpọnwụ.
n'ihu mmepe
Amyotrophic mpụta sclerosis so site dị iche iche ihe n'ịgwa nke ihe ịrịba ama nke mkpọnwụ (bulbar na pseudobulbar). Nke a advantageously gosipụtara dysphagia, na dysarthria, na mgbe e mesịrị na akụkụ okuku ume na ọrịa. A mara mma nke fọrọ nke nta na ụdị nile nke ọrịa na-atụle ga n'oge ike nke n'agba mpiaji. Mgbe ilo na mmiri mmiri na nri dysphagia hụrụ ọtụtụ ugboro karịa na solids. N'otu oge ahụ, ọ ga-kwuru na ihe ndị nke ikpeazụ na N'ezie nke ọrịa progression-aghọ ndị ọzọ siri ike. E nwere a adịghị ike na masticatory mọzụlụ, amalite drooping soft okpo ọnụ, ire na-aghọ atrophic na ofu. Amyotrophic mpụta sclerosis amalite esonyere a na-aga n'ihu eruba n'ime asu, anarthria. Ọ na-aghọ-agaghị ekwe omume ilo, ọ enwekwu ndị likelihood nke ọchịchọ oyi baa. Ọ kwesịkwara kwuru na cramps (intermittent cramps na umu-ehi) a kọrọ na niile ọrịa, na a na-ewere na mbụ ihe ịrịba ama nke ọrịa.
Nkesa nke atrophy
M ga-asị na ọ bụ kama nhọrọ. N'aka nke onye ọrịa na-ekwu meriri hypothenar, thenar, interosseous na deltoids. On ụkwụ atrophy amalite na ebe nke na-arụ mgbehu. Of bulbar uru mebiri emebi anụ ahụ nke na-esighị okpo ọnụ na asụsụ. Oculomotor emep uta eri na-atụle ihe ndị kasị eguzogide atrophy.
bara kwuru
Na daa ọrịa nke obere na-sphincter ọrịa. Otu nke ịtụnanya atụmatụ nke ọrịa bụ enweghị nsogbu ọnyá na ahụ ya kpọnwụrụ akpọnwụ nke a ogologo oge bedridden ọrịa. Ọzọkwa ọ hụrụ na mgbaka na-adị mgbe ọrịa bụ nnọọ obere. Ewezuga kwere nanị ole na ole sub-iche iche: ezinụlọ na mgbagwoju ụdị "parkinsonism-mgbaka AD sclerosis." Kọwara dị ka ikpe ndị metụtara a edo ala ma ọ bụ elu moto akwara ozi. Nke a nwere ike merie imeri onye ọ bụla n'ime ebe. Ka ihe atụ, elu moto neuron nwere ike na-ata ahụhụ ike. Na nke a anyị na-ekwu nke bụ isi mpụta sclerosis. Enwe Mmeri mmebi pụrụ hụrụ ke ala moto akwara ozi. Na nke a anyị na-ekwu okwu nke perednerogovom syndrome.
rheotachygraphy
Usoro a bụ nke akpan akpan na-achọpụta ọrịa uru n'etiti paraclinical ụzọ nke na-amụ ọrịa. Iji EMG ekpughe nile mmebi ihu mpi sel (tinyere na echekwara (clinically) uru ahụ) na fasciculations fibrillation, mgbanwe na potentials nke moto nkeji, a mma-efegharị efegharị megide a nkịtị ọsọ nke Mgbasa nke ndị excitation emep uta eri na sensory irighiri akwara.
nchọpụta nsogbu
Kụziere nnyocha iji chọpụta a daa ọrịa, ị ga-enwe:
- Ihe ịrịba ama nke mmebi nke ala moto akwara ozi. Ọ dị mkpa, akpan akpan, na EMG nkwenye zọpụta (clinically) uru
- Mgbaàmà nke elu moto neuron mmebi ke-aga n'ihu N'ezie.
Maka nchoputa ga-enweghị:
- Sphincter ọrịa.
- Sensory disturbances.
- Parkinson oria.
- Visual impairment.
- Bass tara n'obiọma.
- Mgbaka nke Alzheimer ụdị.
- Autonomic ọrịa.
Diagnosis na-egosi fasciculations na 1 ma ọ bụ karịa zones, EMG ịrịba ama nkịtị ọsọ nke Mgbasa nke ihe excitation sensory na moto emep uta eri. Otu n'ime ihe ndị na edemede ga-kwuru:
- Secure na ALS. Otu ihe atụ na-abịa chọpụta ihe ịrịba ama nke mmerụ na ala moto akwara ozi na n'elu atọ na ebe nke ahu.
- Puru omume. Na nke a, e nwere ihe ịrịba ama nke a lesion na ala na elu moto akwara ozi na abụọ na nke ahu.
- Kwere omume. Ọnya gosiri ihe ịrịba ama nke elu na nke ala moto neuron n'otu ebe nke ahụ ma ọ bụ na-emebi nke abụọ zones 2-3. Na nke ikpeazụ ikpe anyị na-ekwu okwu banyere ngosipụta nke ALS n'otu N'ịdị, aga n'ihu bulbar ụbụrụ na isi ụdị.
Ọgwụgwọ nke Amyotrophic mpụta sclerosis
Taa ndị mbụ na naanị ọgwụ eji daa ọrịa, bụ ụzọ isi "Riluzole". Ọ na-kwadoro na Europe na US, ma na Russia na-adịghị aha na-apụghị-atụ aro ndị ukara dọkịta. Ọgwụ adịghị kpochapụ ọrịa. Ma, ọ bụ naanị ọgwụ nwere a mmetụta dị mma na ndu ndimmadu nke ọrịa. The agwọ ọrịa "Riluzole" na-enyere belata ịta nke glutamate (ọgụgụ akwara mbufe ozi na CNS), tọhapụrụ n'oge Itie a akwara na-akwadoghị akwado. Ngafe nke a compound a hụrụ na kwuru na-ebibi omume na spinal akwara ozi na ụbụrụ. Dị ka ihe Clinical ọmụmụ hụrụ na ndị na-ada ọgwụ, bi na nkezi nke 2-3 ọnwa ogologo oge karịa ndị ji a placebo.
antioxidants
Nke a na klas nke ogige potassium-enyere aka igbochi mmebi nke ahụ nwere ike ime ka free radicals. Ọ na-kweere na a onye na ALS nwere ike ịbụ ihe ọzọ susceptible ka ha ezighị ezi mmetụta. Taa, ọmụmụ na-underway mata, chọpụta mmetụta bara uru Mmeju nwere antioxidants. Ụfọdụ n'ime ndị a na ngwaahịa na ha agafeela ule, okpu iji gosi ya irè.
concomitant ọgwụ
Omume dịgasị iche iche aka ka ndụ dịkwuo mfe n'ihi na ọrịa na-eme ka ọ na ihe na ala. Karịsịa, anyị na-ekwu okwu banyere ntụrụndụ. Ọ na-kweere na reflexology, aromatherapy na ịhịa aka n'ahụ enyere kpochapụ nchegbu ma belata nchegbu, zuru ike mọzụlụ, normalisation nke ọbara na Lymph mgbasa. Ndị a na usoro aka ka tufuo ihe mgbu n'ihi na njikọ nke endogenous mgbu killers emepụta site na ahu na endorphins. Ma ọ bụ na nkà mmụta ọgwụ ma ọ bụ ihe ọ bụla usoro a ga-atụ aro site a dọkịta. Na Amyotrophic mpụta sclerosis onwe-ọgwụ na-adịghị ukwuu tụrụ aro.
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