"Bisoprolol-Prana": egosi maka ojiji, analogs, reviews, ntuziaka maka ojiji. "Bisoprolol-Prana" na "bisoprolol": n'adịghị

E nwere ọtụtụ ọgwụ na ndabere nke bisoprolol, nke na-ọma-eji maka ọgwụgwọ nke ọbara mgbali elu na ọdịda nke obi muscle. N'etiti ha bụ ndị anụ ụlọ ngwaahịa "bisoprolol-Prana".

feature

Emepụta a nhọrọ beta adrenoblokatornoe pụtara Russian ụlọ ọrụ OOO "PRANAFARM".

Ọ na-emepụta na ụdị gburugburu, biconvex mbadamba nwere a nkewa mkpuchi na a film mkpuchi.

Mgbe ị na-eji "bisoprolol-Prana" ntuziaka maka ojiji - nke a bụ ihe mbụ ị na mkpa ịṅa ntị. The ọgwụ dị na ndị na-esonụ Dosages: 5 na 10 mg. Agba shei nta mbadamba icha mmirimmiri odo, na nnukwu - icha mmirimmiri oroma. Nke ọdịnaya nke ọgwụ bụ fọrọ nke nta na-acha ọcha.

Ọdịdị

Otu mbadamba ọgwụ "bisoprolol-Praana" dị ka eme umi nwere 5 na 10 mg bisoprolol hemifumarate. Ọnụnọ nke magnesium stearate, ọka starch, microcrystalline cellulose Ọdịdị, Crospovidone, colloidal sịlịkọn oxide, calcium phosphate dehydrated ụdị na-enye ohere agwọ ọrịa na-enye ndị mkpa solubility na bioavailability.

The film ntekwasa onunu ogwu nke 5 mg ígwè oxide ugbu odo, polyethylene glycol (ọkwa 400), titanium dioxide, silicone. The mkpuchi nke-ekpuchi Erere nnukwu, ọ dị ihe ọzọ colorant n'ụdị red ígwè oxide.

usoro nke ihe

Site nhọrọ beta adrenoblokatornym n'aka ndị na-enweghị ha sympathomimetic ọrụ ụdị, na-agụnye "bisoprolol-Prana". Ntuziaka maka ojiji na-akọwa ya pharmacodynamic e ji mara. The mbadamba nwere mmetụta na Mbelata nsogbu, normalisation nke n'afọ iri na ụma na iwepụ muscle ischemia. Mgbe ekpochi obere Dosages obi ihe nnabata beta ọgwụ adrenozavisimyh 1 bụ a ọnụ mmepụta nke cyclic adenosine monophosphate na calcium ion n'ime cell ugbu a. Ọzọkwa, a ọnụ ke obi ọnụego ma mbenata ya ugboro, na-egbochi ahụ Filiks metụtara na conductivity na excitability.

Hypotensive mmetụta e gosiri na oke ala a uru na-akọwa nkeji olu nke ọbara, na-ebelata mmetụta na elu vaskụla bed. Mbenata elu nsogbu emee mgbe a ụbọchị ole na ole, dị ka mkpa na-akawanye ọnwa abụọ ọgwụgwọ nzọụkwụ.

Antiarrhythmic mmetụta gosi na mkpochapu n'ime ihe ndị mere ndị na-emebi obi otiti. Ndị a gụnyere ndị na steeti tachycardia, enwekwukwa ọrụ nke ọmịiko ụjọ usoro na Department, mụbara etoju nke cyclic adenosine monophosphate, ọbara mgbali elu.

egosi

Tupu iji ọ dị mkpa na-enyocha, n'ihi na nke ìgwè dị iche iche nke ndị ọrịa bụ "bisoprolol-Prana". Egosi jikọtara antianginal mmetụta. Ọ bụ n'ihi na obere mkpa gbasara obi myocardial oxygen ụmụ irighiri site mbenata mkpi ugboro, mụbara ọbara eruba na oge na diastole.

Gịnị bụ ihe nke a ọgwụ ka a Erere "bisoprolol-Prana", site na nke ha na-ewere? Nyere pharmacological e ji mara ha, ha na-eji:

• ọgwụgwọ nke ọbara mgbali;
• ischemic ọrịa obi na ọrịa;
• rịaworo na voltaji;
• maka nke abụọ mgbochi nke myocardial infarction:
• odida nke-adịghị ala ala ụdị.

Ebe isi iche iche nke ọ bụ na-achọsi ike iji "bisoprolol-Praana" ọgwụ ọjọọ. Egosi na-metụtara mkpọchị gbasara obi ịrụ ọrụ. A na-agụnye onye na-abawanye na imi n'afọ iri na ụma, supraventricular na ventricular arrhythmias, na-agbanwe agbanwe obi mitral valvụ protrusion ụdị na hyperthyroidism.

The kpọmkwem ojiji nke ọgwụ

Ntuziaka maka ojiji "bisoprolol-Prana" na-atụ aro na ọgwụ ụtụtụ tupu nri ụtụtụ, dum enweghị Lonely.

Maka ọgwụgwọ nke ọbara mgbali elu, gbasara obi ischemia na-egbochi a ọnọdụ rịaworo iji otu dose na dose mbadamba gụnyere 5 mg bisoprolol. Ọ bụrụ na ọ dị mkpa, na onunu ogwu na-okpukpu abụọ, ma ọ na-nwekwara ike-eji naanị ya. Max bisoprolol ekwesịghị gafere 20 mg kwa norm.

Naanị a dọkịta nwere ike nye iwu ka onunu ogwu na n'ikuku pụtara "bisoprolol-Prana". Egosi ga-soro ntuziaka nke ọgwụ. Tupu nhọpụta nke ego ugboro ole nke contractions nke obi muscle. Ikike na-agbanwe ọnụ ọgụgụ nke mbadamba mgbe amụ ọgwụgwọ omume.

Ọtụtụ ndị ọrịa na-eche banyere ma ọ bụ na o kwere omume "bisoprolol-Prana" bisect. Ọnụnọ nke separator enye ohere iji belata Erere ma ọ bụrụ na ị chọrọ a dị iche iche usoro onunu ogwu.

Iji kpochapụ-adịghị ala ala obi odida ụdị mbụ izu iji 1.25 mg bisoprolol. Dị otú ahụ dose nwere ike enwetara site nkerisi mbadamba nwere 2,5 mg nke nọ n'ọrụ umi. Otú ọ dị, o nwere na-amalite usoro ọgwụgwọ ndị ọzọ na-emeputa, dị ka a n'aka "Bisoprolol-Praana" na-agbala naanị 5 na 10 mg. N'oge nke abụọ n'izu ndinọ 2,5 mg. Na 14 ụbọchị nke ọgwụgwọ site na-ewere 3,75 mg nke ọgwụ. Na-anọ izu na onunu ogwu ama ọkọri 5 mg, na mgbe ọnwa abụọ nke ọgwụ iji 7.5 mg bisoprolol. Iri na abụọ izu na-amalite na a dose nke 10 mg.

Ọ bụrụ na onye ọrịa nwere dị iche iche na ụfọdụ na akụrụ ma ọ bụ imeju, na ụkpụrụ nke creatinine nwechapụ erughị 20 ml maka 1 nkeji, mgbe ahụ, karịa nwere ike ndinọ ruo 10 mg nke ọgwụ.

N'oge ndokwa ọrụ bisoprolol kagbuo maka ụbọchị abụọ, n'ihi ya, ọ na-emetụta ná Nkụnwụ. Ọ bụrụ na mbadamba nkume a mmanya na-egbu, họrọ ndị dị otú ahụ gị n'ụlọnga maka mgbu, nke na-egosipụta inotropic mmetụta, na-ezighị ezi kacha nta ego.

Mgbe otu agadi ndidi bradycardia ime agha obi ọnụego erughị 52 gafere kwa nkeji, ọbara hypotension na systolic ọbara mgbali dị n'okpuru 100 mm HG, bronchospasm, ventricular arrhythmia, nsogbu umeji akụrụ ọrụ, Mbelata a rụrụ dosing ruo mgbe zuru ezu discontinuation. bisoprolol wezụga nwere ike ime ka mmepe nke a dara ya mbà ala, nke e mere site na data nke beta-blocker.

Older ndị adịghị eji a onunu ogwu ukpụhọde.

Zere mberede nkwụsị nke ọgwụgwọ, nke nwere ike ime ka mmepe nke oké arrhythmias ma ọ bụ myocardial infarction ọnọdụ uru. Mwepụ nke ọgwụ na-rụrụ site na-eji nwayọọ nwayọọ mbenata dose maka 14 ụbọchị. Ụbọchị atọ nwere ike belata onunu ogwu site 25%.

Akụkụ nke ọgwụgwọ

Iji jiri "bisoprolol-Prana" ntụziaka na ngwa na-agụnye a ndepụta nke jikoro na-achịkwa ala nke onye ọrịa. Ndị a gụnyere kwa na mbụ nkebi nke definition nke obi ọnụego na ọbara mgbali n'ihe, nke na-ahụ na-enyocha mgbe ọnwa atọ. Ndị ọzọ dị mkpa na-egosi bụ ngwá na ọbara arịa ọrịa shuga, nke tụọ karịa 5 ọnwa.

Older ọrịa chọrọ oge nlekota nke akụrụ, nke na-rụrụ mgbe 4 ọnwa.

Ọgwụgwọ nke-adịghị ala ala obi odida na mbụ nzọụkwụ nke na-anata ala dose-achọ a anọ-hour nyochaa onye ọrịa, nke ugboro ole a na-enyocha site myocardial mkpi, ọbara mgbali electrocardiograms.

Tupu nhọpụta nke ọgwụgwọ na bisoprolol ndidi kụziiri otú gbakọọ obi ọnụego. Na ikpe nke ala ụkpụrụ nke index (ruo 50 gafere kwa nkeji) a chọrọ ọgwụ alo.

Ọzọkwa, na-akọwa ihe "bisoprolol-Prana" ọgwụ ndu-agụnye ozi na mkpa maka ọmụmụ na-ekpebi mpụga ume maka ọrịa na bronchopulmonary ọrịa.

Ọ bụghị ihe niile ọrịa na beta-adrenoblokatornye ọgwụ ọjọọ aka na-emeso rịaworo. Ruru ha inefficiency ọnụnọ nke oké akwara atherosclerosis, ischemic enwe a ala mbata. Na ọnọdụ a, obi ọnụego bụ ihe na-erughị 100 gafere kwa nkeji, na e nwere onye na-abawanye na end-diastolic olu nke ekpe ventricle na mebiri subendocardial ọbara. Ịṅụ Sịga ndị mmadụ bisoprolol-enyekwara njọ.

Ndị na-bronchospastic ọrịa, dị cardioselective kenyere n'aka, ọ bụrụ na e ekweghị ibe nọrọ na ala arụmọrụ na ọgwụ ndị na-ebelata nrụgide. Bụrụ na nke ovadozu nwere ebe a puru nke bronchial spasm.

Mgbe n'imeso ọrịa na thyrotoxicosis beta-blocker, ekwe omume nke masking onye na-adakarị ịrịba ama nke oké thyroid ọrụ, karịsịa tachycardia. Ndị dị otú ahụ ọrịa ike isere a nkọ kagbuo a nkwadebe, na iji gbochie amplification nke ihe mgbaàmà.

Ọ bụrụ na ọrịa na-yi kọntaktị anya, n'ikuku nke bisoprolol nwere ike ime ka a ọnụ ke mmepụta nke adọka ọmụmụ, nke na-achọ ihe ọzọ pụrụ iche anya tụlee instillation.

Mgbe nkwadebe na-eji ọrịa na pheochromocytoma, ọ bụ ike paradoxical ọbara mgbali. N'ọnọdụ dị otú ahụ nke mbido Alfa adrenoblokadnoe edinam.

Ọnụnọ nke-arịa ọrịa shuga masks oké nke tachycardia mere site a ọnụ ke larịị nke glucose dị n'ọbara plasma. Nhọrọ beta-blocker, ọgwụ adịghị ike aka na insulin hypoglycemic ọnọdụ na-egbochi normalisation nke glucose larịị chọrọ ụkpụrụ.

Catecholamines, normetanephrine, antinuclear-alụso ọrịa ọgụ na vanillylmandelic acid na ọbara na mmamịrị kpebisiri naanị na mwepu pụtara "bisoprolol-Praana".

Ime na na lactating inyom, nhọpụta nke ọgwụ e rụrụ-ewere n'ime akaụntụ uru nke nne nwa organism, ma e nwere a-ekwe omume nke oghom mmetụta na ẹmbrayo.

Nke a na ọgwụgwọ a na-contraindicated?

Mbadamba "bisoprolol-Praana" User Ngwa adụ ọdụ iji na dị elu susceptibility, nnukwu ma ọ bụ ala ala decompensated ọrịa nke obi muscle, ujo cardiogenic agwa mgbochi sinuauricular na atrioventricular abụọ na nke atọ ụdị, na syndrome metụtara na adịghị ike na imi ọnụ, onye na-adịghị obi otiti na osisi ike na-erughị 60 gafere.

Contraindication bụ ọnụnọ nke:

• cardiomegaly na-amụba size na ibu ibu nke obi muscle;
• belata nsogbu na akwara nke a systolic uru nke na-erughị 90 mm HG;
• adịghị ala ala okpo ọrịa akpa ume;
• bronchial ụkwara ume ọkụ;
• ọrịa nke ọbara na elu arịa na mgbe e mesịrị nkebi.

achọghị sequela

Medicine "bisoprolol-Praana" nwere ike ime ka dị iche iche mmetụta na-emetụta Central mpaghara na elu ụjọ usoro. Ha na-egosi isi ọwụwa, ike ọgwụgwụ, na-ehi ụra nsogbu ọchịchị, ndị dara mbà n'obi na ọnọdụ na ịmụ anya arọ nrọ.

Ekwesighi Filiks ke obi na ọbara arịa ruru ka orthostatic hypotension, flushing, sweating, palpitations egbu oge na ya erughị eru myocardial ọrụ.

Ndị ọzọ bụ ngosipụta nke mmetụta bụ iji belata secretion nke lacrimal glands, conjunctivitis ịzụlite, afọ ọsịsa, itching nke anụ ahụ, afọ ntachi, ọgbụgbọ, muscle n'adịghị ike na cramps. Okpo mgbaàmà nwere ike ime na bronchi.

yiri preparty

Original ngwá ọrụ na ndabere nke bisoprolol bụ mbadamba "Concor". Ha na-emepụta site German ụlọ ọrụ "Merck".

Na ndabere nke a ọgwụ e mepụtara dị otú ahụ preparations, nwere dị ka ọrụ umi akụrụngwa bisoprolol fumarate.

Russian ọgwụ emepụta emepụta beta-blockers na dị iche iche ahia aha. Otu ihe atụ ga-a n'aka "Bisoprolol-Praana": ya analogs nwere a onunu ogwu nke 2.5 mg, 5 mg na 10 mg. Ọgwụ ndị a na-agụnye mbadamba:

• "Bisogamma";
• "Niperten";
• "Kordinorm";
• "Biprol".

Ngwá ọrụ ndị a na-emepụta site mba ọzọ ụlọ ọrụ. Na-emepụta ọgwụ ahịa ọnọde ngwaahịa, aha nke bụ ugbu aha nke enterprise, n'ihi na ihe atụ, "bisoprolol-Teva", "bisoprolol-Ratiopharm," "bisoprolol-Sandoz", "bisoprolol-ING."

E nwere analogues, nke na-akpọ nanị "bisoprolol". Ndị dị otú ahụ ọgwụ arụpụtara site Russian osisi: JSC "Vertex", JSC "North Star", LLC "Ozone Pharmaceuticals", JSC "Biocom".

Ọ bụrụ na anyị na-atụnyere ndị Erere "bisoprolol" na "bisoprolol-Prana", ihe dị iche ga-qualitative na quantitative mejupụtara inyeaka mmiri. Ndịrịta iche dị otú adịghị emetụta permeability na bioavailability nke nọ n'ọrụ umi ke idem, n'ihi ya, na ọgwụgwọ mmetụta nke ọgwụ ga-abụ otu.

Nyocha

Ọtụtụ ndị ọrịa na-achọpụta na mma nke iji ọgwụ nwere bisoprolol, n'ihi na ha na-ewe otu ugboro n'ụbọchị. Otu mbadamba bụ ezuru a dum ụbọchị maka normalisation nke ọbara mgbali.

About pụtara "bisoprolol-Prana" ezi reviews. Ha na-egosi nke elu selectivity, nke bụ ya mere mkpụrụ ọgwụ na-esonyere ole na ole oghom mmetụta tụnyere ndị ọzọ beta-blockers.

Ọrịa mara usability na obere mmetụta na-eme ka mgbanwe nke ụfọdụ ndị ọrịa maka ọgwụgwọ dị ka ọgwụ.

Men na-ekwu na ọgwụ adịghị eme ka nsogbu nke potency. Ke adianade do, nke a bụ eziokwu na e gosipụtara site ọtụtụ nnyocha.

Drug "bisoprolol-Prana" na-egosi metabolic na-anọpụ iche na-akwanyere ùgwù cholesterol, triglyceride na glucose metabolism. Nke a onwunwe-enye anyị ohere nye iwu ya ọrịa na nke abụọ ụdị ọrịa shuga ma ọ bụ a pụrụ ịrịa ụba glucose etoju ke ọbara. Ntem, dị ọrịa na-ahapụ mma nzaghachi banyere ọgwụ.

N'ihi na obere ọnụ ọgụgụ nke oghom Jeremaya mere ọgwụ kenyere ka ọrịa na ndị agadi. Ọrịa na-ekwu na ọgwụ nrụpụta na nchekwa nke ọzọ antihypertensives Beta blokatornogo usoro.

The uru nke ọgwụ ọjọọ, "bisoprolol-Prana" bụ ya ala price, nke bụ ngwa ngwa dị ka ala-ego ndị mmadụ, nke a na-egosi na ekele na-azaghachi.

Ma, n'agbanyeghị na niile uru nke mbadamba, naanị a dọkịta nwere ike nye iwu ka ha dabeere na nnyocha e mere na-arụpụta.