Glycosylated haemoglobin - a amanyere bụ iwu nke ule maka nchoputa nke ọrịa shuga mellitus na nwale nke larịị nke ya ụgwọ

Na ọgwụ omume e nwere otu mgbe inwale irè nke glucose-ẹsụhọde ọgwụ, na adequacy nke kenyere ọgwụgwọ na ọrịa na-arịa ọrịa shuga mellitus nwere ike isi ike. O yiri ka a na onye na-ele nke ọma, na-ebu ọnụ glucose na ya nkịtị, ma ihe bụ likelihood nke nsogbu na a ndidi? Mgbe niile, ego nke glucose dị n'ọbara na-na inyocha na oge nke na-amụ ihe, nke a na ọnụ ọgụgụ otu ugboro.

Mgbe ụfọdụ, na-amụba ọbara glucose etoju dị ike ndị mmadụ, n'ihi na ihe atụ, mgbe ha natasịrị a nnukwu ego nke carbohydrates ma ọ bụ oké echiche na inwe obi nchegbu. On sugar etoju pụrụ imetụta oriri nke ụfọdụ ọgwụ, ndị dị ka ọnụ na gbochie afọ, ụfọdụ diuretics, psychiatric ọgwụ ọjọọ. Na niile siri ike ikpe na-enyemaka nke ihe endocrinologist Analysis maka glycated haemoglobin, na ntụziaka nke nchoputa, ọ na-ezo dị ka HbA1c.

Glycosylated haemoglobin - nke a pụta na ụmụ irighiri ihe nke glucose na haemoglobin A, ejikari usoro a na-ewe ebe nọgidere na ndị ahụ siri ike. The ego nke haemoglobin na emume glycation - 5-8%. Na ọrịa na-arịa ọrịa shuga, nke a na ọnụ ọgụgụ na-abawanye site 2-3 ugboro arịọsikwa ofụri ndụ nke ọbara uhie cell, ie, 120 ụbọchị. N'ihi na ọbara nwere ma-eto eto na tozuru okè red corpuscles, ya mere, e nkezi afọ ndụ nke ọbara uhie cell, nke bụ hà a ọkara nke ndụ ya - 60 ụbọchị.

Glycosylated haemoglobin, ọnụego nke bụ 4-6.1% nke ngụkọta haemoglobin larịị, na-egosi na nkezi glucose ruo ọnwa abụọ ruo mgbe ọbara ule. Ya mere, ọ bụ omume na-ekpebi ma na-adịte abawanye na glucose ma ọ bụ n'ime 2 ọnwa nke a index nọ kwesịrị ikwu. Mmekọrịta dị n'etiti HbA1c na glucose dị n'ọbara bụ afọ nke nnyocha, empirically kpebisiri na-abawanye na ọbara glucose na 1,59 mmol / l kwa 1% haemoglobin doro glycation.

Mgbe ụfọdụ, ndị kenyere ule maka glycated haemoglobin?

- maka Ịchọpụta Otú Nsogbu arịa ọrịa shuga na-akọwapụta ya larịị nke akwụ ụgwọ;

- nyochaa ọgwụgwọ nke hypoglycemic mmadụ ;

- iji chọpụta ihe ize ndụ nke vaskụla nsogbu nke ọrịa shuga;

- N'ọnọdụ nile nke isi glucose ndidi na nchoputa nke tupu ọrịa shuga;

- ime ndị inyom na-na n'ihe ize ndụ nke na-emepe emepe-arịa ọrịa shuga.

Interpretation nke ule results maka ọrịa shuga:

Iji 5.8% - arịa ọrịa shuga na-ọma ụgwọ atụrụ.

Site 8 na 10% - obere ụgwọ atụrụ arịa ọrịa shuga.

N'elu 12% - ọjọọ mmerụ ọrịa.

Endocrinology agbalị họrọ ọgwụ nke na glycated haemoglobin bụ na nso nke 7 na 8%. Mgbe kwesịrị ekwesị ọgwụ ọgwụgwọ elu HbA1c larịị afiakde nkịtị otu ọnwa mgbe ukpụhọde.

The American Diabetes Association na-atụ aro a ọmụmụ rụrụ dịghị obere ugboro ugboro karịrị ọ bụla 6 ọnwa. Na Russia, na analysis of HbA1c na e kenyere ya niile ọrịa na-anata insulin na hypoglycemic ọgwụ ọjọọ, ozugbo ọ bụla 3 ọnwa. Dị ka larịị nke haemoglobin HbA1c nwere ike ikpe ma elu puru nke ime daa ọrịa nke retinal microvessels, akụrụ mmebi, na akwara ozi.

N'oge ụfọdụ, o kwere omume distortion analysis HbA1c?

Ụgha elu pụta hụrụ na-amụba na ọkwa nke nwa ebu n'afọ na haemoglobin n'ime ọbara na ígwè erughi anaemia. Ụgha egosi ahụrụ ọnụ mgbaji ọkpụkpụ ruru hemolysis nke erythrocytes mgbe ọbara ma ọ bụ ọbara gwụrụ.

Analysis maka glycated haemoglobin kenyere dịtụ ọzọ (1 kwa ọnwa) na ọrịa ndị na-nwere abụghị ọkọlọtọ N'ezie nke ọrịa, ma ọ bụrụ na ha nwere oké concomitant ọrịa, ụmụ nwaanyị dị ime na-arịa ọrịa shuga iji gbochie mmepe nke ọrịa na nke nwa ebu n'afọ.