Hypothalamic atọhapụ homonụ

Atọhapụ homonụ bụ ụmụ mmadụ neurohormone na-synthesized hypothalamic ntọala. Ha inhibit (statins) ma ọ bụ na-akpali (liberiny) mmepụta tropic pituitary homonụ. Ọ activates endocrine glands, na e nwere iwu nke ntọhapụ nke homonụ. The elu akụkụ nke Central ụjọ usoro na endocrine usoro na-anya metụtara n'ihi na nke-atọhapụ homonụ.

hypothalamic ọrụ

Otu n'ime ihe dị mkpa mmiri nke na endocrine usoro maka mmepụta nke homonụ - na hypothalamus. Mepụtara site na hypothalamus bekee homonụ abuana ke metabolic Filiks nke ahu.

Na hypothalamus e nwere akwara mkpụrụ ndụ na-hụ na mmepụta nke dị mkpa bekee ndị ahụ mkpa maka kwesịrị ịrụ ọrụ. Ndị a na mkpụrụ ndụ na-akpọ neurosecretory. Ọrụ ha - na-enweta pulses na-ebunye n'akụkụ dị iche iche nke ụjọ usoro. Nweghị ọcha pụtara site aksovazalnye synapses.

Mepụtara hypothalamic atọhapụ homonụ, ma ọ bụ dị ka na-akpọ ha dị iche iche, statins na liberiny, dị oké mkpa maka kwesịrị ịrụ ọrụ nke pituitary gland. Site ha chemical uwa, ha na-peptides. N'ihi chemical na akwara esi gboo ha njikọ ha, ha na-ebu n'ime ọbara site na pituitary hypothalamic-pituitary usoro.

nhazi ọkwa nke homonụ

Tụlee kasị mma-mara atọhapụ homonụ:

• Inhibiting ndị secretion nke pituitary ọrụ - ọ bụ a somatostatin melanostatin, prolaktostatine.
• Stimulant - na anyị na-ekwu okwu banyere melanoliberine, prolaktoliberine, folliberine, lyuliberine, somatoliberin, thyrotropin-atọhapụ hormone, gonadotropin-atọhapụ hormone na corticotropin.

Ndị bekee, ma ọ bụ kama ụfọdụ n'ime ha, nwere ike Olee ihe enyemaka na-emepụta site na ndị ọzọ ozu, ọ bụghị naanị hypothalamus (e.g., pancreas).

Statins na liberiny

Ịrụ ọrụ nke pituitary gland bụ kpọmkwem dabere na ha. ha nwere mmetụta na ịrụ ọrụ nke elu endocrine glands:

• thyroid;
• ovaries na ụmụ agbọghọ;
• testes na ụmụ nwoke.

Statins na liberiny nke kasị mara amara bụ:

• dopamine;
• GnRH (lyuliberin, folliberin);
• melonostatin;
• somatostatin;
• tireoliberin.

The secretion nke luteinizing hormone na follicle-akpali akpali homonụ nke pituitary GnRH enye.

On ọrụ nke androgen na ndị ikom na-emetụta GnRH, na-eme ka onye na-abawanye nke spam ọrụ na larịị nke libido.

Na ndị inyom neurohormone maka ịhụ nsọ okirikiri, ego nke homonụ dịgasị na-adọ nke okirikiri ya.

Ezughi oke mmepụta nke atọhapụ homonụ na-akpatakarị infertility na enweghi ike.

Njirimara homonụ

Corticotropin hormone maka mmetụta nke nchegbu, na-emepụta site na hypothalamus. Nke a bụ ihe ọzọ dị mkpa atọhapụ akpata, eme na njikọ na pituitary homonụ na mmetụta ha na adrenal glands. Ndị na-enweghị ihe a hormone mgbe ata ahụhụ site na ọbara mgbali elu, na adrenal insufficiency.

GnRH - a hormone na enhances na mmepụta nke gonadotropins - nwekwara a ngwaahịa nke hypothalamus. Ọ na-akpọ gonadotropin-atọhapụ hormone.

The kwesịrị ịrụ ọrụ nke omumu akụkụ nwere ike ime na-enweghị GnRH. Ọ bụ nke a hormone bụ maka na eke N'ezie nke ịhụ nsọ okirikiri na nwanyi. Na ya na-ekere òkè na-ewe ebe usoro nke maturation na ntọhapụ nke ndị egg. Nke a hormone bụ maka libido (mmekọahụ mbanye). Mgbe e ezughi oke mmepụta nke hormone site hypothalamus na ọtụtụ mgbe ndị inyom ịzụlite infertility. Olee ihe ọzọ na-atọhapụ homonụ?

somatoliberin

Kasị ngwa ngwa tọhapụrụ n'ime nwata na-eto eto. Ya isi mma bụ usoro nke normalisation nke ngwa ibu na ahụ na usoro. Si ya mmepụta adabere full mmepe na guzobe nke nwa. Ezughi oke mmepụta nke hormone si hypothalamus pụrụ iduga dwarfism (dwarfism).

Prolaktoliberin

Ya kasị ike mmepe emee n'oge gestation na ofụri nri oge nke nwa nne ya. Nke a-atọhapụ akpata apụta na mmepụta nke prolactin, akpụ ducts nke mammary glands.

Prolaktostatin

Prolaktostatin na-ezo aka a subclass nke statins emepụta site na hypothalamus, bụ maka na mgbochi nke prolactin.

Site prolaktostatinam na-agụnye:

· Dopamine;

· Somatostatin;

· Melanostatin.

Ha isi edinam iji na n'igbochi na tropic homonụ nke pituitary na hypothalamus.

Melanotropin-atọhapụ hormone

Na usoro nke melanin ink na nkewa nke mkpụrụ ndụ na-emetụta melanoliberin. Ọ na-eme na ihe nke DWP pituitary.

Mmetụta neurophysiological omume. Ọ na-eji maka wepụ ọgwụgwọ nke dara ya mbà na-ekwu na parkinsonism.

Thyrotropin-atọhapụ hormone (TRH)

Site thyrotropin-atọhapụ homonụ nke hypothalamus metụtakwara thyroliberine. Ọ na-akwalite mmepụta nke homonụ nke ihu pituitary thyritropic.

Iji a obere n'ókè-ekpebi usoro nke prolactin. Thyroliberine enhances ịta nke thyroxine ke iyịp.

CNS nwere oké mmetụta na usoro nke mmepụta nke homonụ. N'ihi na mmepụta nke neurohormones bụ ọrụ neurosecretory cell usoro iwu usoro.

Basic ọrụ liberinov

Nke a hypothalamic atọhapụ homonụ. Igosi usoro iwu ọrụ. GnRH normalize ịrụ ọrụ nke omumu usoro nke ndị inyom na ndị ikom.

Ha na-ahụ maka ndị mmeputakwa nke follicle-akpali akpali hormone na-emetụta ọrụ nke testes na ovaries.

Ndị dị otú ahụ akụrụngwa dị ka lyuliberin sụgharịrị, na-anọ naanị mmetụta ovulation, akpụ ekwe omume nwa ebu n'afọ na a tụụrụ ime ya.

Inyom bụ ndị na-enweghị mmasị na-akpachi anya na ndụ, na lyuliberin folliberin emepụta ezughi oke quantities.

E nwekwara-atọhapụ ihe metụtara ndị nkezi òkè nke hypothalamus, ma ha njikọ ahụ pituitary ihu pituitary sel adịghị mụọ.

Agonists atọhapụ hormone: ọgwụ ọjọọ

Dị ka e kwuworo, a homonụ na-emepụta site na hypothalamus. Mgbe ọ na-chọrọ na-akpali ndị ovaries, n'ihi na ihe atụ tupu IVF usoro, eji agonists ma ọ bụ corticotropin atọhapụ hormone analogs. Ya bụ, ha nwere na ozu otu mmetụta dị ka ya hormone.

Ma Ohere nke oghom Jeremaya mere na akụkụ nke nne ahụ. Nke a na-eme n'ihi na ala estrogen etoju. The kasị mmetụta na-agụnye:

• isi ọwụwa;
• oké sweating;
• na-ekpo ọkụ mgbukepụ;
• mmamiri nkụ;
• ọnọdụ swings;
• ịda mbà n'obi.

Ọgwụ ọjọọ na-eji dị ka ndị a:

• "Diferelin" bụ ihe na wuru decapeptide analogue nke eke hormone atọhapụ.
• "Dekapeptil" dị ka akụkụ nke a triptorelin, keakamere analogue nke GnRH. The ọkara ndụ ogologo. Mgbe eji maka keakamere insemination.
• "Lyukrin ebusa" - leuprorelin. Ọ nwere mgbochi estrogen, mgbochi androgenic mmetụta, gwọọkwa endometriosis, hormone-ndabere etuto ahụ - cancer nke prostate, eriri akpa nwa fibroids. "Lyukrin ebusa" ebelata ịta nke testosterone na ndị ikom, estradiol na ndị inyom, ke adianade do, na-egbochi incretia pituitary FSH, LH.
• Mmetụta nke ọgwụ nwayọọ nwayọọ weghachiri n'ahụ secretion nke homonụ.
• 'Zoladex' - sịntetik analogue nke a eke hormone-atọhapụ hormone (LH). Ejikarị na IVF. Ebelata ịta nke estradiol na ọbara, nke a emee n'ihi suppression nke LH secretion nke ihu pituitary.
  

Anyị kwurịtara preparations agonists atọhapụ hormone.

akụ ọkpọ

Ebe ọ bụ na mgbe na-anata atọhapụ hormone agonists abawanye ukwuu estradiol nwere ike ime mberede ntọhapụ nke luteinizing hormone. Nke a na-eduga ná akaghi aka ovulation na mbibi nke àkwá. Iji zere nke a, ndị na-akụ ọkpọ atọhapụ hormone were. N'ihi nke omume ha pụrụ akpali ndị pituitary gland ọzọ. Ovarian hyperstimulation syndrome anaghị egosipụta onwe, ma ọ bụ na-adịkarị n'ihi na ruo ogologo oge iji GnRH agonists. Na-ndinọ n'ime ụbọchị ise site na mmalite nke na ngwa nke follicle na-akpali akpali hormone.

Iji ọgwụ bụ ihe ịga nke ọma, na-nzube preparations kwesịrị ịbụ naanị a ọkachamara.