"Thiotriazoline": ntuziaka maka ojiji

Ị banye ọgwụ "Thiotriazoline"? na ojiji nke a ọgwụ ndu ga-kọwara n'ụzọ zuru ezu na ugbu isiokwu. Ke adianade do, anyị ga-agwa gị banyere ụdị nke ọgwụ abatakwa kwuru ire ere, nke ọ nwere na-egosi, mmetụta na contraindications.

The mejupụtara nke ọgwụ nkwakọ na ntọhapụ ụdị

Na ihe ụdị ntọhapụ agwọ ọrịa "Thiotriazoline"? Ntuziaka na-agwa na o nwere ọtụtụ dị iche iche iche-iche. The kasị ewu ewu bụ:

• A ngwọta zubere maka intramuscular na igba ogwu n'akwara ogwu ogbugba. 1 ml nke gị n'ụlọnga nwere 0,025 g Thiotriazoline. Ọzọkwa a agwọ ọrịa na ịnara mmiri n'ụdị mmiri ogwu ogbugba. The ọgwụ dị na 4 ml ampoules (enịm ke katọn).
• "Thiotriazoline" anya tụlee. Site n'iji ndị dị otú ahụ a na ndu pụtara na-enye na 5 ml nwere 50 mg nke iji ọgwụ Thiotriazoline, nakwa dị ka ndị ọzọ bekee. The ọgwụ na-eresị na plastic karama, droppers, enịm ke a kaadiboodu igbe.
• "Thiotriazoline" mkpụrụ ọgwụ. Ntuziaka ka a n'ụdị ọgwụ na-enye na n'otu ọcha okirikiri mbadamba na a ewepụghị elu ẹdude 100 mg morfoliniymetiltriazoliltioatsetata, ma ọ bụ na-akpọ Thiotriazoline. Dị ka ndị ọzọ mmiri nke agwọ ọrịa eme nduku starch, microcrystalline cellulose, ala molekụla ibu povidone, calcium stearate na sucrose. Dị ka a na-achị, na a katọn ngwugwu nwere 50 mbadamba.

pharmacodynamics

Gịnị bụ ihe ngwọta dị ka "Thiotriazoline"? Ntuziaka maka Iji na-ekwu na nke a antioxidant ọgwụ. Ya elu arụmọrụ bụ n'ihi na antioxidant, antiischemic, immunomodulatory na akpụkpọ ahụ kwụsie ike Njirimara.

E lee ya anya ọgwụ na-egbochi mbibi nke hepatocytes, na-eme ka ha na mgbake, ebelata ogo nke ọdụdụ infiltration, dapụtara na normalisation nke protein, carbohydrate, lipid na ink mgbanwe, na ebelata likelihood nke mgbasa nke necrosis tsentrolobulyarnyh a ahụ dị ka umeji. Ọzọkwa, ifịk ifịk ọgwụ mma iche na njikọ nke bile, apụta ya mejupụtara (chemical).

Njirimara nke ọgwụ

Olee otú nwere Njirimara nke ọgwụ ọjọọ, "Thiotriazoline"? Ntuziaka maka ojiji nke ọgwụ a chọrọ maka ịgụ. Mgbe niile, naanị site na ya, ị pụrụ ịmụta banyere ihe ndị na-ewere ọgwụ ọjọọ na lowers mgbochi nke oxidative Filiks na Krebs okirikiri, na-edebe intracellular ATP enweta ego, nakwa dị ka enhances ebighị (compensatory) anaerobic glycolysis.

Ọzọkwa mara na mgbe na-ewere ọgwụ ọjọọ na-arụsi ọrụ ike umi-amalite iji rụọ ọrụ antioxidant usoro, abụba inhibit oxidative Filiks ke ischemic ebe nke ahu. Ke adianade do, a ọgwụ mma Njirimara (rheology) ọbara ruru ka ebighị nke fibrinolytic usoro.

The antioxidant Njirimara nke ọgwụ na-egosipụta site na eziokwu na Ọdịdị nke molekul bụ tiotrazolina sọlfọ ion, ji ọxịdashọn na Mbelata atụmatụ, dị ka nke ọma dị ka tertiary nitrogen, nke na-ejikọ gabigara ego nke hydrogen ion.

Anyị ga na-ekwukwa na-arụsi ọrụ ike iji ọgwụ akụrụngwa nwere ike na-eme na lipid radicals na reactive oxygen umu. Nke a bụ n'ihi na a akpọ Mbelata Njirimara nke thiol otu. Ke adianade do, agwọ ọrịa na-egbochi guzobe reactive oxygen umu, ndị dị otú ahụ antiradical reactivating enzymes ka catalase, glutathione peroxidase na superoxide dismutase.

Pharmacokinetics

Ma ọgwụ etinye obi gị dum "Thiotriazoline"? Ntụziaka na-ekwu na oge poluabsorbtsii ọgwụ bụ 30 nkeji na bioavailability - 65,5%.

Oke ọbara ịta n'aka na-enweta site na 1.4 awa mgbe ochichi. Communication na-edozi adịghị gafere 10%.

Buru ibu, ọgwụ accumulates na anụ ahụ nke imeju, obi, colon, splin na-na akụrụ, na obere - na obere eriri afọ na akpa ume. Thiotriazoline anyụpụ tumadi site na akụrụ ya.

na-agba akaebe

Ọ bụrụ na e na-deviations nwere ike kenyere ọgwụ, injections na anya tụlee "Thiotriazoline"? na ojiji nke ndị a iche-iche nke ntụziaka na-egosi ndị na-esonụ na-egosi:

• imeju;
• na-egbu egbu imeju mmebi, aṅụrụma, malitere ịrịa, na ọgwụ ọjọọ (e.g., mgbe ha natasịrị ọgwụ nje, antiviral ọgwụ ọjọọ eme ihe, mgbochi TB na mgbochi akpụ mmadụ, onu gbochie afọ na tricyclic antidepressants);
• adịghị ala ala malitere ịrịa ịba ọcha n'anya;
• mmanya na ịba ọcha n'anya -adịghị ala ala na-agafeghị oke ka ntakiri ọrụ;
• imeju abụba mbelata.

Egosi maka ojiji tụlee:

• corneal ọrịa;
• Burns ma ọ bụ anya unan;
• malitere ịrịa conjunctivitis.

Mere ka na-eji ophthalmic ọgwụ "Thiotriazoline"? Ntuziaka (tụlee ike zụrụ na bụla ahịa ọgwụ ahụ) na-agwa na a ọgwụ a na-kenyere mgbochi nke akọrọ anya, eyestrain, na ndị ọzọ na mkpali oria visual akụkụ.

The onunu ogwu mbadamba

Olee otú m ga na-eji "Thiotriazoline" mbadamba? Manual nwere ọmụma na ọgwụ kwesịrị iwere naanị n'ime. Dị ka a na-achị, thiotriazolin inye 1 ma ọ bụ 2 mbadamba ugboro anọ a ụbọchị maka 25-30 ụbọchị.

Na oge nke ọgwụgwọ na a gị n'ụlọnga ga-ekpebisi ike site a dọkịta na n'otu n'otu (dabere na N'ezie na ogo nke ẹdude ọrịa).

The ọgwụ ngwọta "Thiotriazoline": ntuziaka maka ojiji

Ọgwụ "Thiotriazoline" ime intramuscularly ma ọ bụ intravenously. Ha onunu ogwu kpebisiri ike site dibịa (dabere na ọrịa). Myocardial infarction na ịba ọcha n'anya ọgwụ nwayọọ nwayọọ agbara intravenously na 2 ml 2-3 ugboro n'ụbọchị. Na imeju agwọ ọrịa na-ndinọ intramuscularly (2 ml 2-3 ugboro n'ụbọchị). The ọgwụgwọ bụ ụbọchị 60.

Anya tụlee "Thiotriazoline": ntuziaka maka ojiji

Anya tụlee "Thiotriazoline" kụnyere n'ime conjunctival nwa. Na-emekarị, na onunu ogwu n'ihi na ndị okenye bụ 2 tụlee nke aka 4 ugboro n'ụbọchị. Banyere ụmụaka, ego nke ọgwụ kpebisiri ike naanị site a pediatrician. Na oge nke ọgwụgwọ na anya tụlee na a ga-arụnyere na site na ịga dibịa.

Dị ka a na-achị, oge nke ọgwụgwọ na ngwá ọrụ a na-adịghị karịa izu 2. Ma ọ bụrụ na ọ dịghị mma na-hụrụ, na N'ezie nwere ike gbasaa ruo a ọnwa.

N'ihe banyere ọtụtụ ọnya visual akụkụ, na oké njọ, mgbe ahụ, dropwise adianade ocular injections ndinọ (ọzọ preparations).

N'ihi mgbochi nke ihicha nke anya membranes (na-arụ ọrụ na a na kọmputa), ị ga-eji a na nkà mmụta ọgwụ 2 tụlee n'oge ụbọchị na otu nkeji nke 2 awa.

mmetụta

Gịnị bụ mmetụta nke ọgwụ nwere ike ime ka "Thiotriazoline" (gbaa)? Ntuziaka ka usoro a na-egosi na ọgwụ na-ọma na-anabata na-akwanyere. Otú ọ dị, na-eji na-ewere ọgwụ ka nwere ike ime undesired Jeremaya mere.

• Central ụjọ usoro: dizziness, adịghị ike, ịkụ na nti.
• Digestive tract: akọrọ ọnụ, ọgbụgbọ, bloating.
• Arịa na obi, mụbara ọbara mgbali, tachycardia, arrhythmia, obi mgbu.
• Akụkụ okuku ume na usoro: ụkwara ume ọkụ na iku ume ọkụ ọkụ.
• Allergy: fever, hypersensitivity Jeremaya mere, angioedema.
• Obodo Jeremaya mere: nācha ọbara-ọbara na tingling sensashion na ọgwụ na saịtị.
• Dermatological Jeremaya mere: akpụkpọ flushing, itching, aṅụ.

Ma anya tụlee, na na ha n'akụkụ mmetụta na-hụrụ.

ọgwụ interactions

Dị ka ndị ọkachamara, ọgwụ "Thiotriazoline" ike ga-eji na njikọ na isi ọgwụ zubere maka ọgwụgwọ nke ịrịa ọrịa obi. Nke a bụ n'ihi na eziokwu na kwuru ọgwụ bụ a cardioprotective n'ụlọnga.

Ọ kwesịkwara kwuru na ọgwụ na-ekwe na-eji n'out oge na ọgwụ na-kenyere ọgwụgwọ kwesịrị ekwesị nke ịba ọcha n'anya etiology.

Anya tụlee "Thiotriazoline" nwere ike e kenyere ụmụ nwaanyị dị ime na n'oge lactation. Ọ kwesịkwara kwuru na udi nke kwuru na ngwaahịa na-ekwe na-eji na njikọ na ndị ọzọ ike n'aka.

Mmanya na ọgwụ ọjọọ "Tiatriazolin" na-eme ọ bụla ọzọ si eme. Na nke a, ha concomitant amachibidoro.

adọ aka ná ntị

The mejupụtara agụnye sucrose atụle mbadamba (ke ichekwa 2.8 mg kwa mbadamba). N'ihi ya, iji karịa kwa ụbọchị dose nke ọgwụ nwere ike ibu banyere 22,4 mg nke umi. Eziokwu a kwesịrị ịma ọrịa, ọrịa na-arịa ọrịa shuga mellitus.

The ụzọ na oge nke nchekwa

Nnọọ niile forms "Tiatriazolin" ọgwụ ga-echebe site ìhè na-apụghị iru nke ụmụaka na okpomọkụ nke 14 ruo 26 degrees. Adị ndụ nke ọgwụ bụ 3 afọ.