"5-NOC" - reviews nkwadebe

N'agbanyeghị eziokwu na ahụ mmadụ na-nyere na ọgụ na-enwe ike ịnagide ọtụtụ ọrịa naanị, e nwere bacteria na-efe efe na pụrụ imeri naanị na enyemaka nke ọgwụ. Ndị dị otú ahụ ọgwụ ọjọọ nwere ike inhibit ma ọ bụ kwụsị uto nke pathogenic ntule, si otú iwepu na-elekwasị anya nke mbufụt. Mbadamba bụ "5-NOC" The ìgwè nke ndị dị otú ahụ ọgwụ ọjọọ. Nleba egosi ha elu nrụpụta na ọgwụgwọ nke ọrịa na nke genitourinary usoro. Ke adianade do, nke a na ngwá ọrụ bụ zuru okè n'ihi na mgbochi nke nlọghachite nke mbufụt ke adịghị ala ala iche-iche nke ọrịa.

Active umi

Nitroxoline ifịk umi bụ ifịk ọgwụ "NOC-5." Ọ bụ a sịntetik guzobere, a emepụta nke 8-hydroxyquinoline. Site na nke a akụrụngwa, ọgwụ na-abanye ga-amalite ịchọ mkpụrụ ndụ nke microorganisms na inhibit ha DNA. nhọrọ usoro nke edinam na-enye ohere iji kwụsị mmụba nke pathogenic bacteria na agaghị emerụ ahụ ike mkpụrụ ndụ.

E wezụga nitroksolin abatakwa n'ime mmeghachi omume na-arụsi ọrụ ike nucleic asịd na enzymes nke nwere ọla-ha ngịga. The umi enye mgbake usoro nke pathogenic bacteria nwere ike bactericidal ihe megide a dịgasị iche iche nke microorganisms. N'ihi ya, ọ dị irè na-eme megide pụta eguzogide ọgwụ ọjọọ ndị ọzọ dị iche iche nke ọgwụ nje. Medicine "NOC-5 'Fim na-egosi ụzọ dị irè na ọnụ ụzọ megide ọrịa ndị dịkwa ka usoro ha, nje bacteria, na-akpata ọrịa pathogens elu iguzogide ndị ọzọ ọgwụ ọjọọ nke antibacterial na antiseptik edinam.

Hapụ ụdị na mejupụtara

The agwọ ọrịa atara n'ụdị ntekwasa mbadamba. Ha nwere oroma ma ọ bụ acha odo odo, na ụdị nke gburugburu, lenticular, e nwere ihe e ji mara luster. Isi nọ n'ọrụ mgwa - nitroksolin. Inyeaka mmiri nke mejupụtara: sucrose, colorant E110, carboxymethylcellulose, lactose.

Gịnị microorganisms na-alụ ọgụ ọgwụ

Rịba ama na Nwa nwere a directional mmetụta na bụ nnọọ irè megide ụfọdụ nje pathogens:

• Aerobic na anaerobic gram-mma ntule - Enterococcus faecalis, streptococcus spp. (Pneumoniae pụta, pyogenes).
• Staphylococcus spp., Pụta aureus, nje na-akpata subtilis, Corynebacterium spp.
• Anaerobic na aerobic microorganisms (gram) - Klebsiella spp, Proteus spp, Shigella spp, Salmonella spp, Haemophilus influenzae, Enterobacter spp, Escherichia coli, Neisseria gonorrhoeae ......
• Na-efe efe kpatara nke Mycobacterium ụkwara nta, nke Mycoplasma hominis, Trichomonas vaginalis, nke Ureaplasma urealyticum.

Ebu, dermatophytes, dịkwa ka usoro ha nke Candida, ụfọdụ ntule na-eme ka miri fungal-efe efe - ọrịa ndị a na-irè na mbenata ọgwụ "5-NOC". Nyocha nke dọkịta na-egosi ikike nke ọgwụ iji belata adhesion nke uropathogenic ntule na mgbidi nke catheter (ka igbapu mmamịrị si ọrịa) na urinary tract epithelial oyi akwa.

mgbe ndinọ

N'ihi a kama dịgasị iche iche nke ọgwụ ngwa iji nagide ndị na-esonụ ọrịa:

• Adịghị ala ala, nnukwu, ntighari ọrịa (na-efe efe etiology) urinary tract mere site gram-adịghị mma na gram-mma bacteria na fungi.
• Epididymitis.
• Pyelonephritis: ala ala na nnukwu ụdị.
• Urethritis.
• Cystitis.
• Adenoma na carcinoma (ezi) nke prostate.
• Igbochi na-efe efe (ntighari) urinary tract.
• Tee mgbe achọpụta ọrịa na usoro ịwa ahụ na urinary tract: akụrụ usiakidem, cystoscopy, catheterization.

Ọ bụ uru na-arịba ama na idepụta ezigbo ọgwụgwọ dabere na ogo nke ọrịa nwere ike ịbụ naanị na a dọkịta. Mbadamba "5-NOC" ọkachamara reviews ọ na-egosi na elu bioavailability - banyere 90%. Ha na-ngwa ngwa etinye obi gị dum na eriri afọ tract na iru kasị elu plasma ịta n'ime 1.5-2 awa.

Pharmacokinetics

The nkwadebe nwere a ala ike ikpokọta na plasma-edozi. The kasị elu ịta nke nọ n'ọrụ umi gosiri na mmamịrị nke onye ọrịa. The ọgwụ na-metabolized isi na imeju na-na-anyụpụ site na akụrụ ya. A ụfọdụ ego nke ọgwụ a na-ewepụ si ahụ na bile - a oge nke 2 awa ga-ahụ kwuru na data na pharmacokinetics nke ọgwụ na ụmụaka, ndị mmadụ na agadi na ọrịa na gbasara akụrụ insufficiency na imeju na e mụọ .. Ya mere, ị ga-enweta a dọkịta maara oge tupu prescribing mkpụrụ ọgwụ "5-NOC". Nyocha ọkachamara kwuru na ụmụaka nnọọ nke ọma na-anabata ọgwụ bụrụ na nke zuru nnabata ya na onunu ogwu na ọgwụgwọ regimens. Akpan akpan elekọta kwesịrị iduga nwa chọpụtara, bụ nke na-ahụ ruru afọ 3.

Olee na-

Ọ na-atụ aro na-ọgwụ n'oge nri ma ọ bụ mgbe ya. Mbadamba adịghị ata, ilo dum, asa ala na mmiri dị ọcha. Ezigbo doses:

• Okenye ọrịa - 100 na 200 mg, ruo 4 ugboro n'ụbọchị. Rịba ama na n'okpuru ọnọdụ nke na-aga n'ihu na ojiji nke mbadamba ọnụego nwere ike gafere ụbọchị 30. Otú ọ dị, o kwere omume ọmụmụ nke ọgwụ na eri oké nri: 14 ụbọchị na-aṅụ mbadamba, 14 ụbọchị anaraghị ọgwụ. Nke a na usoro na-eme ka o kwe omume na-enye ọgwụgwọ maka ọtụtụ ọnwa.
• Prevention of na-efe efe ọrịa mgbe usoro ịwa ahụ, na-achọpụta ọrịa usoro - 100 mg aka 4 ugboro n'ụbọchị. Dị otú ahụ agwọ ọrịa n'ikuku mode dịruru ruo 3 izu. N'ihi na ọrịa na mkpọchị imeju ọrụ na akụrụ mbụ dose bụ 50% nke na-atụ aro.

Ọ ga-kwuru na ọgwụ bụ "5-NOC" na cystitis, ndidi testimonials gosi na nke a, ngwa ngwa na-ebelata mbufụt na eliminates nkọ mgbu. Otú ọ dị, ọbụna na ihe omume nke a mmetụta dị mma nke ọgwụgwọ na-adịghị na-atụ aro ka ịkwụsịtụ N'ezie kenyere onye dọkịta, ma ọ bụghị n'ebe ihe ize ndụ nke nlọghachite.

The onunu ogwu maka ụmụaka

Buru n'uche na ihe zuru ezu onunu ogwu maka a na nwa nwere ike mata na a dọkịta na ndabere nke nnyocha e mere. ọgwụ na-emekarị kenyere dị ka ndị a:

• Nwa ọhụrụ si 2 ọnwa 12 ngụkọta oge na-mere, dabeere na nwa ahu arọ: 25 mg / n'arọ kwa ụbọchị. All ọgwụ ga-ekewa 4 doses na mgbe etiti oge. Duration nke ọgwụ bụ site 10 ụbọchị 3 izu. Bụrụ na nke oké ọrịa - elu 1 ọnwa.
• Mgbe ọ dị afọ 12 na ọnwa na afọ 14 ọgwụ oriri nke 50 ruo 100 mg aka 4 ugboro n'ụbọchị. Ọ na-ekpebisi ike site a ọkachamara, ma na-aga n'ihu n'ikuku ya nwere ike gafere ụbọchị 30. Mgbe interleaved mode 2 izu - n'ikuku, na 2 izu - a ezumike na-ekwe maka a ogologo ojiji nke ọgwụ ọjọọ, "5-NOC". Children, dọkịta reviews banyere nke a show n'aka ga-kenyere naanị na oké njọ mgbe ọgwụgwọ na ndị ọzọ ọgwụ owụt adighi ike.

Ekwe Omume mmetụta

Rịba ama na mmetụta na ndị ọrịa bụ ndị obere, ma ọ dị mkpa na ihe omume nke ha omume ozigbo a dọkịta. Na o nwere ike ịkagbu ọgwụ na-eduzi symptomatic omume mgbe omume "5-NOC". Ntụziaka reviews ndị dọkịta na-atụ aro ndị na-esonụ na-adịghị mma ngosipụta na ọgwụgwọ nke:

• Vomiting, ndiiche imeju ọrụ, ọgbụgbọ, anorexia, na obere okwu.
• Tachycardia.
• Paresthesia, polyneuropathy.
• Mkpọchị nchikota, dizziness, isi ọwụwa, mgbe ụfọdụ, na ọnwụ nke nsụhọ.
• Optic neuritis (na ruo ogologo oge iji mbadamba).
• Urticaria, ọkụ ọkụ, ekpepụsị akpụkpọ.
• Thrombocytopenia, mgbe ụfọdụ, mmamịrị staining na miri-acha odo odo hue, na-abawanye na uric acid index n'ime ọbara plasma.

Dị ka a na-achị, ihe niile oghom ihe rue ngwa ngwa mgbe zuru ezu discontinuation nke ọgwụ, "5-NOC". Nleba-egosi gị na-eche adịchaghị, naanị na ikpe nke na ovadozu ma ọ bụ ogbenye nnabata.

contraindications

Ọ bụrụ na onye ọrịa nwere adịghị anabata ma ọ bụ na uche ka otu n'ime mmiri nke na mejupụtara, a machibidoro iwu ekenye ọgwụ. Ọ na-adịghị atụ aro iji na-etinye agwọ ọrịa na ara, cataracts, ndiiche imeju ọrụ na akụrụ.

Ọ bụ uru na-arịba ama na ọgwụ bụ "5-NOC" inyom nzaghachi banyere nke a show na-kenyere n'oge ime. Ọ na-adịghị guzosie ike ikpe nke nsogbu ahụ ike nke ma ndị ga-eme n'ọdịnihu nne na nwa ebu n'afọ. A, ọgwụ na-kenyere nnukwu cystitis, mmamiri na-efe efe na fungal ngosipụta (thrush).

Ọ dịghị mkpa na-na nkà mmụta ọgwụ na n'otu oge ahụ na ọgwụ na-ebu hydroxyquinoline. na-egbu egbu nsi nwere ike ime site na a njuputa nke nọ n'ọrụ umi ke idem.