Calcium Citrate: njirimara, usoro mmemme, ngwa

Otutu Ca na okenye (ihe dị ka 99%) dị na anụ ọkpụkpụ n'ime ngwongwo hydroxyapatite. Na ọbara kasị mammals, calcium ịta bụ banyere 3 mmol / l (10-12 mg / 100 ml) na bụ mgbe nile. Mgbanwe ọ bụla nke oge a anaghị aba pasent 3-5%. Ca dị mkpa maka ịrụ ọrụ nke usoro ụjọ ahụ. Na synapses neuromuscular, akwara calcium na-enye aka na ntọhapụ nke acetylcholine na nchikota ya na choptor choline, na n'ihu ọnụ nke acetylcholine, cholinesterase, enzyme nke hydrolyses acetylcholine, na-arụ ọrụ.

Ca ions, nke dị na reticulum sarcoplasmic, na-akwalite mmekọrịta nke actin na myosin, ya bụ, mgbagha nke eriri ahụ. Enwere mmetụta a na ọnụnọ ion ion magnesium.

Calcium na-eme ka mmekorita enzymatic rụọ ọrụ n'oge mbụ nke ọbara - ka e guzobere thromboplastin na thrombin. Njikọ Ca ions na plasma na oxalates ma ọ bụ citrates na-egbochi coagulation nke ọbara.

N'oge na-adịbeghị anya, e gosipụtara ọrụ calcium pụrụ iche na ọrụ dị mkpa nke mkpụrụ ndụ, na cytoplasm nke ịta ya anaghị eru 10-6 mol. N'elu ọkwa cellular, usoro ihe omimi nke isii dị iche iche, nke dabere na ịta Ca ions:

A) ihe omuma nke mkpụrụ ndụ (mgbachi nke akwara);

b) ndị excitability nke mkpụrụ ndụ nke na-enwe ike n'ịwa electrostatic edinam nwere (Akwara ụda, akwara na-akwadoghị akwado photoreception gbasara obi mkpi);

C) nkwụsị nke ihe ndị e mepụtara na cell (ihe nzuzo nke hormones na neurotransmitters);

D) ịbanye n'ime sel nke ihe ndị nwere ike ịmepụta site na ịṅụ ọgwụ (phagocytosis);

E) intracellular metabolism (njikọ nke glucose, lipolysis, wdg);

E) mmeputakwa mkpụrụ ndụ (ịme fatịlaịza na mitosis nke àkwá, motility nke spermatozoa).

Ca ions na protein ndị a kapịrị ọnụ na-enye nhazi na ike nke ọkpụkpụ ọkpụkpụ. Nkà mmụta ọgwụ ọgbara eji ọtụtụ preparations nwere ion nke calcium (glyukanat, citrate, chloride, lactate, carbonate, phosphate, wdg). Calcium citrate dị ezigbo mkpa. Okpokoro isi nke calcium nke a na-esi n'ime ya (phosphates, sulfates, chlorides) na-emepụta ihe oriri na mmiri na-edozi n'ime afo n'okpuru nduzi nke chloride acid na enzymes proteolytic. Carbonic na phosphoric acid salts calcium dissociate na mmiri acidic nke afọ, na calcium na ionized ụdị ma ọ bụ na ya na chelates soluble abatakwa obere eriri afọ. Ya mere, na a belatara secretory ọrụ nke afo nnweta Ca mmiri bụ ezughi oke, ọ pụrụ ịbụ otu n'ime ihe ndị mere na mpe nke a mmewere ke idem. Calcium citrate kachasị mma nke ọma na gburugburu acidic nke afọ. Ionized calcium ngwa ngwa penetrates ndu membranes, ọbụna site na Plasenta mgbochi. Akụkụ nke mbụ (ihe dị ka 80%) nke calcium na-esi n'ahụ ya pụọ na mpaghara fecal, na ihe dị ka pasent 20 nke mmepụta mmamịrị. N'ihi na calcium citrate kama citrate nnu akwalite Mbelata nke oxalate na mmamịrị, na ojiji nke ọgwụ ọjọọ emeghị ka e guzobere akụrụ itiat.

A chọpụtara na n'oge abalị, a na-eme ka salts ịnweta pụọ n'ahụ. Ya mere, ndị dọkịta na-akwado ikpo calcium citrate mgbe nri abalị ma ọ bụ na mgbede. A chọpụtara mmekọrịta dị njọ n'etiti ọgwụ ọgwụ na ọrụ ọgwụ nke calcium. Nso ke emi ọwọrọ? Calcium citrate kachasị etinye uche na ahụ na obere doses. Ya mere, ọ kacha mma ịṅụ ọgwụ ọtụtụ ugboro n'ụbọchị. A na-eguzobe usoro nhazi nke usoro calcium kwa afọ. Calcium kenyere ka a preventative na ọgwụgwọ (rickets, osteoporosis, osteomalacia, maka ike eze Enamel) nzube. A na-etinye potassium potassium maka citrate maka ọrịa obi, ọbara mgbali elu, maka normalization nke acid na isi na nnu nnu n'ime ahụ.