Imeju fibrosis: akpata, ụdị, ọgwụgwọ

Imeju fibrosis bụ nwayọọ nwayọọ nnọchi nke imeju mkpụrụ ndụ site connective anụ ahụ, na-akpata oké mmepụta nke nsụkọta. Hepatic fibrosis e mere site isi ọbara na hepatic akwara, na iche na imeju e ji zuru enweghị cell imu. The ọrịa amalite nnọọ nwayọọ nwayọọ, ọ na-adịghị na-egosipụta onwe, ie. E. Asymptomatic. The mbụ mgbaàmà na-egosipụta nanị mgbe isii afọ asatọ.

Ugbu were ọtụtụ ihe nke imeju fibrosis. Ndị a gụnyere: ogologo oge ọgwụ, na mmanya na nsi na-egbu egbu, butere n'aka, congenital fibrosis, ala ala malitere ịrịa ịba ọcha n'anya, ọrịa shuga, ibu oké ibu, ruo ogologo oge erughi nke ụfọdụ minerals na vitamin.

Mmepe nke imeju fibrosis na-eduga ná ndị dị otú ahụ ọtọ na bughi pụta dị ka mebiri Filiks mgbanwe n'etiti ọbara na hepatocytes na sinusoids, shunting ọbara, Ọrụ mmepe nke imeju, ọnwụ nke arụmọrụ na ibelata ụdịdị dị iche iche nke ọgwụgwọ na-eme.

Dabere na usoro na ya omume orunótu iche ndị na-esonụ iche nke ọrịa:

- perivenulyarny na venular fibrosis na-amalite na etiti nke mmasị na n'elu mgbidi nke hepatic veins. The kasị mara nke ụdị fibrosis maka ala ala ọrịa obi na-adịghị ala ala na-aba ịba ọcha n'anya;

- pericellular fibrosis. Ọtụtụ mgbe hụrụ na mmanya na ọrịa imeju na-adịghị ala ala malitere ịrịa ịba ọcha n'anya;

- septal imeju fibrosis na emee mpaghara bridging necrosis;

- a portal na periportal hepatic fibrosis, nke bụ ihe e ji mara atụmatụ nke-adịghị ala ala ịba ọcha n'anya nke dị iche iche si dị: malitere ịrịa, autoimmune ma ọ bụ mmanya;

- periductal (gbasara obi) imeju fibrosis hụrụ na ọrịa sclerosing cholangitis na ndị concentric proliferation nke fibrous anụ ahụ gburugburu bile dị iche iche caliber tubules;

- Mixed fibrosis bụ ihe kasị nkịtị ụdị, na nke na-ọkọnọ ụdị ndị ọzọ nke fibrosis dị iche iche oke.

Isi mgbaàmà nke imeju fibrosis pụta ìhè ruo mgbe a afọ ole na ole mgbe mmalite nke ọrịa na-:

- ọnụnọ nke na-agba ọbara si esophageal varices;

- amụba size nke imeju;

- mmụba nke splin;

- thrombocytopenia.

Imeju fibrosis bụ nnọọ ike na-emeso, nke a na-emekarị na-eduzi na-agbazi ẹdude ọrịa ọrịamkpokọta. Na ọnụnọ nke gosiri hypersplenism rụrụ splenectomy na imposition nke splenorenal anastomosis. Iji kwụsị ọbara na-agba site na dilated dị ka a n'ihi nke varicose veins nke afo na nkọlọ, endoscopy ma ọ bụ sclerotherapy nke veins gastrotomy na kpachie.

Prevention of hepatic fibrosis bụ mkpofu àgwà ọjọọ, na-ebelata ọgwụ bụghị, ma ọ bụrụ na ibu - na-ewere jikoro tufuo ya, na-akpụ akpụ nri ezi oriri na-edozi. Ọzọkwa na-atụ aro supplementation nke Chọpụta ọcha na vitamin. N'elu nchọpụta nke imeju fibrosis ga ebelata ibu arọ na imeju, mepụta mgbe ochichi nke ọgwụ ọjọọ na-enyere sachapụ umeji anyụpụ n'ozuzu, nakwa dị ka normalisation nke ya ọrụ. Prognosis na-adabere n'ụzọ dị ukwuu na ihe ụdị fibrosis mepụtara. Congenital fibrosis ụdị bụ nnọọ obere.

Cheta na hepatic fibrosis amalite n'enweghị ihe mgbaàmà maka ọtụtụ afọ, ruo mgbe mmepe nke imeju, ma ọ bụrụ na ị na-chọpụtara na "ịba ọcha n'anya" ma ọ bụ ọ bụrụ na ị nwere mmebi imeju, e nwere a elu puru nke pụrụ ịrịa nke imeju fibrosis usoro.